sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xhx | T5M | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2xhx | T5M | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.590 | |
| 2xjg | XJG | Heat shock protein HSP 90-alpha | / | 0.580 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.537 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.526 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.522 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.518 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.511 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.510 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.498 | |
| 3ied | AN2 | HSP90 | / | 0.497 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 2wi2 | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.493 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.492 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.492 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.491 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.489 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.484 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.477 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.476 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.473 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2o1v | ADP | Endoplasmin | / | 0.472 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.472 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.471 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.469 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.468 | |
| 2o1u | ANP | Endoplasmin | / | 0.467 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.466 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.465 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.465 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2ye9 | 2D4 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.464 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.463 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.463 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.462 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.462 | |
| 1osv | CHC | Bile acid receptor | / | 0.461 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.460 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.459 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.459 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.458 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.458 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.458 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.457 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.456 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.456 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.456 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.455 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.455 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3ieu | GDP | GTPase Era | / | 0.455 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.454 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.454 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.454 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.453 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3lps | NOV | DNA topoisomerase 4 subunit B | / | 0.453 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.453 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.453 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.452 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.452 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.452 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.452 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.452 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.452 | |
| 3u04 | BB2 | Peptide deformylase | / | 0.452 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.452 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.451 | |
| 1xal | NAD | 3-dehydroquinate synthase | / | 0.451 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.451 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.450 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.450 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.450 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.449 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.449 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.449 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.448 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.448 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.448 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.448 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.448 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.448 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.448 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.447 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.447 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.447 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.447 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.447 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.446 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.446 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.446 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.446 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.446 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.446 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.445 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.445 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3p0j | TYE | Putative tyrosyl-tRNA synthetase | / | 0.445 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.445 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.445 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.444 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.444 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.444 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.444 | |
| 4yqf | GDP | Septin-9 | / | 0.444 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.443 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.443 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.443 | |
| 4yak | ACO | Acyl-CoA synthetase (NDP forming) | / | 0.443 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 5a3b | APR | SIR2 family protein | / | 0.443 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.442 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1s16 | ANP | DNA topoisomerase 4 subunit B | / | 0.442 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.442 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.442 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.441 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.441 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.441 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 3ft5 | MO8 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.441 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.441 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.441 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.441 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.441 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.441 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.441 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.440 | |
| 2ccu | 2D9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3amf | FMN | FMN-binding protein | / | 0.440 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 4die | C5P | Cytidylate kinase | / | 0.440 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.440 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |