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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2ittAEEEpidermal growth factor receptor2.7.10.10.556
2jedLG8Protein kinase C theta type2.7.11.130.545
3iw4LW4Protein kinase C alpha type2.7.11.130.532
4qms1N1Serine/threonine-protein kinase 242.7.11.10.529
4riyADPEpidermal growth factor receptor2.7.10.10.528
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
1zrzBI1Protein kinase C iota type2.7.11.130.520
2itnANPEpidermal growth factor receptor2.7.10.10.517
2hog710Serine/threonine-protein kinase Chk12.7.11.10.515
4wboANWRhodopsin kinase/0.513
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.512
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.511
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.510
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.510
4jr3KJREpidermal growth factor receptor2.7.10.10.510
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.509
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.509
4qnaX11Serine/threonine-protein kinase 242.7.11.10.507
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.507
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.506
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.506
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.506
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.505
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.505
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.504
2balPQAMitogen-activated protein kinase 14/0.503
2itpAEEEpidermal growth factor receptor2.7.10.10.503
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.503
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.502
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.501
2acxANPG protein-coupled receptor kinase 62.7.11.160.501
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.501
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.501
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.501
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.500
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.500
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.500
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.499
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.499
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.498
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.498
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.498
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.497
2vd5BI8Myotonin-protein kinase2.7.11.10.496
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.495
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.495
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.495
4jq7KJQEpidermal growth factor receptor2.7.10.10.495
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.493
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.493
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.493
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.492
4jq8KJ8Epidermal growth factor receptor2.7.10.10.492
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.492
1m17AQ4Epidermal growth factor receptor2.7.10.10.491
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.491
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.491
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.491
4i22IREEpidermal growth factor receptor2.7.10.10.491
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.491
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.490
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.490
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.489
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.489
4jrvKJVEpidermal growth factor receptor2.7.10.10.489
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.488
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.488
2itvANPEpidermal growth factor receptor2.7.10.10.488
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.488
3vjoANPEpidermal growth factor receptor2.7.10.10.488
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.487
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.487
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.487
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.486
4i231C9Epidermal growth factor receptor2.7.10.10.486
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.485
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.485
3nj0PYVAbscisic acid receptor PYL2/0.485
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.485
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.484
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.484
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.483
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.483
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.483
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.482
2yn8STUEphrin type-B receptor 42.7.10.10.482
3fklFKLMitogen-activated protein kinase 14/0.482
4aa4QC0Mitogen-activated protein kinase 14/0.482
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.482
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.481
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.481
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.480
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.480
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.480
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.480
3fln3FNMitogen-activated protein kinase 14/0.480
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.479
2itwITQEpidermal growth factor receptor2.7.10.10.479
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.479
4aacAAVMitogen-activated protein kinase 14/0.479
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
2of2547Tyrosine-protein kinase Lck2.7.10.20.478
4g2fC07Ephrin type-A receptor 32.7.10.10.478
4qmzB49Serine/threonine-protein kinase 242.7.11.10.478
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.477
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.476
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.476
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.476
4b99R4LMitogen-activated protein kinase 72.7.11.240.476
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.476
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.476
4gg70J8Hepatocyte growth factor receptor2.7.10.10.476
4hjoAQ4Epidermal growth factor receptor2.7.10.10.476
4wkqIREEpidermal growth factor receptor2.7.10.10.476
3a62STURibosomal protein S6 kinase beta-12.7.11.10.475
3nww3NWMitogen-activated protein kinase 14/0.475
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.475
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.475
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.474
2xyuQ9GEphrin type-A receptor 42.7.10.10.474
3dt1P40Mitogen-activated protein kinase 14/0.474
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.474
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.474
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.472
3mvm39PMitogen-activated protein kinase 14/0.472
4fob0USALK tyrosine kinase receptor2.7.10.10.472
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.472
4kba1QMCasein kinase I isoform delta2.7.11.10.472
3a7hATPSerine/threonine-protein kinase 242.7.11.10.471
2hk51BMTyrosine-protein kinase HCK2.7.10.20.470
2i0ePDSProtein kinase C beta type2.7.11.130.470
3mpt1GKMitogen-activated protein kinase 14/0.470
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.470
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.470
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.469
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.469
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.469
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.469
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.469
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.469
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.469
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
4qo9627Serine/threonine-protein kinase 242.7.11.10.468
2qo9ANPEphrin type-A receptor 32.7.10.10.467
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.467
3lctADPALK tyrosine kinase receptor2.7.10.10.467
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.467
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
2y6o1N1Ephrin type-A receptor 42.7.10.10.466
4gk3L87Ephrin type-A receptor 32.7.10.10.466
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
5e8xSTUTGF-beta receptor type-12.7.11.300.466
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.465
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.465
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.465
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.465
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.465
3du8553Glycogen synthase kinase-3 beta2.7.11.260.465
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.465
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.465
4nks2M2Fibroblast growth factor receptor 1/0.465
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.465
2ituITQEpidermal growth factor receptor2.7.10.10.464
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.464
4aa5NQBMitogen-activated protein kinase 14/0.464
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.464
4lopSB4Mitogen-activated protein kinase 14/0.464
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.463
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.463
3ac1KZITyrosine-protein kinase Lck2.7.10.20.463
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.463
4c02TAKActivin receptor type-12.7.11.300.463
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
1xjdSTUProtein kinase C theta type2.7.11.130.462
2wxvWXVCyclin-dependent kinase 22.7.11.220.462
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.462
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.462
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.462
4gmy0X5Tyrosine-protein kinase JAK2/0.462
5e8wSTUTGF-beta receptor type-12.7.11.300.462
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.461
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.461
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.461
4fuxE75Mitogen-activated protein kinase 12.7.11.240.461
3ac2KSETyrosine-protein kinase Lck2.7.10.20.460
3biz61EWee1-like protein kinase2.7.10.20.460
3s4qNK0Mitogen-activated protein kinase 14/0.460
3zze6XPHepatocyte growth factor receptor2.7.10.10.460
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.460
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.459
3t8oATPRhodopsin kinase/0.459
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.459
4kip1R9Mitogen-activated protein kinase 14/0.459
5aacVGHALK tyrosine kinase receptor2.7.10.10.459
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.458
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.458
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.458
3gc9B45Mitogen-activated protein kinase 112.7.11.240.458
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.458
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.458
4bchT7ZCyclin-dependent kinase 92.7.11.220.458
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.458
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.457
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.457
3hl7I47Mitogen-activated protein kinase 14/0.457
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.457
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.457
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.457
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.457
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.456
2wotZZGTGF-beta receptor type-12.7.11.300.456
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.456
3iphG11Mitogen-activated protein kinase 14/0.456
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.456
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.456
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.456
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.456
4j97ACPFibroblast growth factor receptor 2/0.456
4yuqKS1Calmodulin-like domain protein kinase/0.456
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.455
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.455
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.455
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.455
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.455
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.455
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.455
4eh60ONMitogen-activated protein kinase 14/0.455
4iebANPCalmodulin-domain protein kinase 1/0.455
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.454
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.454
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3w32W32Epidermal growth factor receptor2.7.10.10.454
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.454
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.454
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.454
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.454
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.453
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
2j7t274Serine/threonine-protein kinase 102.7.11.10.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
3bqr4RBDeath-associated protein kinase 3/0.453
3umw596Serine/threonine-protein kinase pim-12.7.11.10.453
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.453
4gk2L66Ephrin type-A receptor 32.7.10.10.453
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.453
4nka2K7Fibroblast growth factor receptor 1/0.453
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.453
1bygSTUTyrosine-protein kinase CSK/0.452
1klkPMDDihydrofolate reductase1.5.1.30.452
2bfyH1NAurora kinase B-A2.7.11.10.452
2gr1FADFerredoxin reductase/0.452
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.452
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.452
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.452
3lqfNADGalactitol dehydrogenase/0.452
3mvl38PMitogen-activated protein kinase 14/0.452
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4fv9E71Mitogen-activated protein kinase 12.7.11.240.452
4hnf16WCasein kinase I isoform delta2.7.11.10.452
4hni16WCasein kinase I isoform epsilon2.7.11.10.452
4kiq1RAMitogen-activated protein kinase 14/0.452
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
2j0j4STFocal adhesion kinase 12.7.10.20.451
2wipP49Cyclin-dependent kinase 22.7.11.220.451
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.451
4c4jX21Dual specificity protein kinase TTK2.7.12.10.451
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.451
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.451
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.450
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.450
3c4xATPRhodopsin kinase/0.450
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.450
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.450
4cdmFO1Deoxyribodipyrimidine photolyase/0.450
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4kak06UDihydrofolate reductase1.5.1.30.450
2of4979Tyrosine-protein kinase Lck2.7.10.20.449
2vwx7X4Ephrin type-B receptor 42.7.10.10.449
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.449
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.449
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.449
3gubGUBDeath-associated protein kinase 12.7.11.10.449
3kf7L9GMitogen-activated protein kinase 14/0.449
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.449
3w33W19Epidermal growth factor receptor2.7.10.10.449
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.449
4ienCOAPutative acyl-CoA hydrolase/0.449
4kbc1QJCasein kinase I isoform delta2.7.11.10.449
1fm4DXCMajor pollen allergen Bet v 1-L/0.448
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1zys199Serine/threonine-protein kinase Chk12.7.11.10.448
2c475IDCasein kinase I isoform gamma-2/0.448
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.448
2uzlC94Cyclin-dependent kinase 22.7.11.220.448
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.448
4erkOLOMitogen-activated protein kinase 12.7.11.240.448
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.448
4kbk1QGCasein kinase I isoform delta2.7.11.10.448
1jpaANPEphrin type-B receptor 22.7.10.10.447
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.447
2eb3ANPEpidermal growth factor receptor2.7.10.10.447
2j0k4STFocal adhesion kinase 12.7.10.20.447
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.447
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.447
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.447
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4deg0JJHepatocyte growth factor receptor2.7.10.10.447
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.447
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1kzkJE2Gag-Pol polyprotein3.4.23.160.446
2ghlLIBMitogen-activated protein kinase 14/0.446
2j0m4STFocal adhesion kinase 12.7.10.20.446
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
4anqVGHALK tyrosine kinase receptor2.7.10.10.446
4c4h7RODual specificity protein kinase TTK2.7.12.10.446
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.446
4kb81QNCasein kinase I isoform delta2.7.11.10.446
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.445
2itqITQEpidermal growth factor receptor2.7.10.10.445
2izrBRKCasein kinase I isoform gamma-32.7.11.10.445
2p5uNADUDP-glucose 4-epimerase/0.445
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.445
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.445
3zewSTUEphrin type-B receptor 42.7.10.10.445
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.445
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.445
5eccNAPDehydrofolate reductase type I/0.445
1kl2FONSerine hydroxymethyltransferase/0.444
2chlDKICasein kinase I isoform gamma-32.7.11.10.444
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.444
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.444
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.444
2znpK55Peroxisome proliferator-activated receptor delta/0.444
3drcMTXDihydrofolate reductase1.5.1.30.444
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.444
3uq9TBNPutative adenosine kinase/0.444
3wv9FEGHmd co-occurring protein HcgE/0.444
4bcqTJFCyclin-dependent kinase 22.7.11.220.444
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.444
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
2ckeIQUDeath-associated protein kinase 2/0.443
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.443
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.443
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.443
3vryB43Tyrosine-protein kinase HCK2.7.10.20.443
4cd0AWJALK tyrosine kinase receptor2.7.10.10.443
4dfrMTXDihydrofolate reductase1.5.1.30.443
4kb81QOCasein kinase I isoform delta2.7.11.10.443
4looSB4Mitogen-activated protein kinase 14/0.443
5a3bAPRSIR2 family protein/0.443
1pjkANPCasein kinase II subunit alpha2.7.11.10.442
1u54ACPActivated CDC42 kinase 1/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2py3ACPFibroblast growth factor receptor 2/0.442
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.442
3hx4ANPCalmodulin-domain protein kinase 1/0.442
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.442
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.442
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1ao8MTXDihydrofolate reductase1.5.1.30.441
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.441
1ywrLI9Mitogen-activated protein kinase 14/0.441
2xp2VGHALK tyrosine kinase receptor2.7.10.10.441
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.441
3d7kD7KBenzaldehyde lyase/0.441
3flzFLZMitogen-activated protein kinase 14/0.441
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.441
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.441
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.441
4ansVGHALK tyrosine kinase receptor2.7.10.10.441
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.441
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.441
1k6tXN1Gag-Pol polyprotein3.4.23.160.440
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.440
2fgiPD1Fibroblast growth factor receptor 1/0.440
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.440
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.440
4l4cCAMCamphor 5-monooxygenase1.14.15.10.440
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.440