Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3uow | XMP | GMP synthase [glutamine-hydrolyzing] |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3uow | XMP | GMP synthase [glutamine-hydrolyzing] | / | 1.000 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.504 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.491 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.489 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.488 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 5da9 | AGS | Uncharacterized protein | / | 0.488 | |
| 2qtg | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 | 3.2.2.9 | 0.484 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.482 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.482 | |
| 4jlo | ADP | Adenylate kinase | / | 0.478 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.478 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.477 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.475 | |
| 3k3b | ADP | Kinesin-like protein KIF11 | / | 0.475 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.475 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.474 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.474 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.473 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 4nu6 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.472 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.471 | |
| 5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.471 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.470 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.470 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.469 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.468 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.468 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.468 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.468 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.467 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.467 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.466 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3eel | 53T | Uncharacterized protein | / | 0.466 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.466 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.465 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.465 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.465 | |
| 3orp | AGS | Serine/threonine protein kinase | / | 0.464 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.463 | |
| 3zxt | ACP | Death-associated protein kinase 1 | 2.7.11.1 | 0.463 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.463 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.463 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.463 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.462 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.462 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.461 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.461 | |
| 4ike | ADP | Adenylate kinase | / | 0.461 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.461 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.460 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3pjt | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.460 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.460 | |
| 4coj | DTP | Uncharacterized protein | / | 0.460 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.460 | |
| 4xzm | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.460 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.460 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.459 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.459 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3stx | BKA | Methylketone synthase I | / | 0.459 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.459 | |
| 4pd6 | URI | Nucleoside permease | / | 0.459 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.458 | |
| 2ji8 | FYN | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.458 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2w4i | VGA | Glutamate racemase | / | 0.458 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.458 | |
| 4a28 | ADP | Kinesin-like protein KIF11 | / | 0.458 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.458 | |
| 1hk2 | T44 | Serum albumin | / | 0.457 | |
| 1rj9 | GCP | Signal recognition particle receptor FtsY | / | 0.457 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.457 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.457 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.457 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.457 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.457 | |
| 5dmz | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.457 | |
| 5l8l | ADP | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.456 | |
| 1osv | CHC | Bile acid receptor | / | 0.456 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.456 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.456 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.456 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.455 | |
| 3bej | MUF | Bile acid receptor | / | 0.455 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.455 | |
| 4cta | ATP | CinA-like protein | / | 0.455 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.455 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.454 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.454 | |
| 3wd7 | COA | Acridone synthase | / | 0.454 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.454 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.454 | |
| 5ce3 | ADP | Protein kinase YopO | / | 0.454 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.453 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.453 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.453 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.453 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.453 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.453 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.452 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.452 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 2cdu | FAD | NADH oxidase | / | 0.452 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.452 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.452 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.452 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.452 | |
| 4apu | A2K | Progesterone receptor | / | 0.452 | |
| 4jld | ADP | Adenylate kinase | / | 0.452 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.452 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.451 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.451 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.451 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.451 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.451 | |
| 4l9q | 9TP | Serum albumin | / | 0.451 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.450 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2gqr | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.450 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.450 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.450 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.450 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.450 | |
| 4pl4 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.450 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.450 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1ict | T44 | Transthyretin | / | 0.449 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.449 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.449 | |
| 4hi0 | GDP | Urease accessory protein UreG | / | 0.449 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.449 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.449 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.448 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.448 | |
| 2bx8 | AZQ | Serum albumin | / | 0.448 | |
| 2bxm | IMN | Serum albumin | / | 0.448 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.448 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.448 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.448 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.448 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.448 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ppj | ANY | Cytochrome b | / | 0.447 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.447 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.447 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
| 3nnx | EDD | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3tdl | 11D | Serum albumin | / | 0.447 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.447 | |
| 4mob | COA | Acyl-coenzyme A thioesterase 12 | 3.1.2.1 | 0.447 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.447 | |
| 1e1x | NW1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.446 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.446 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.446 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3q8x | UD1 | Toxin zeta | / | 0.446 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.446 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.446 | |
| 4fnz | NZF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.446 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.445 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.445 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.445 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.445 | |
| 2c69 | CT8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 2r38 | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.445 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.445 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4f07 | FAD | Styrene monooxygenase component 2 | / | 0.445 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.445 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.445 | |
| 5cb4 | ACP | Tubulin tyrosine ligase | / | 0.445 | |
| 1bve | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 1sn5 | T3 | Transthyretin | / | 0.444 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.444 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.444 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.444 | |
| 2puu | G2G | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.444 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.444 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.444 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.444 | |
| 4a9r | RU5 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 4bi1 | ZO6 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.444 | |
| 4dea | NHI | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.444 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.444 | |
| 4z69 | DIF | Serum albumin | / | 0.444 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.443 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.443 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2y3r | TIR | TamL | / | 0.443 | |
| 3a6r | FMN | FMN-binding protein | / | 0.443 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.443 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.443 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.443 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 3x2v | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.443 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.443 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
| 1ie4 | T44 | Transthyretin | / | 0.442 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.442 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1pkg | ADP | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.442 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.442 | |
| 1u80 | C5P | Coenzyme A biosynthesis bifunctional protein CoaBC | 6.3.2.5 | 0.442 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.442 | |
| 2aru | ATP | Lipoate-protein ligase A subunit 1 | / | 0.442 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.442 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3hji | FAD | Vivid PAS protein VVD | / | 0.442 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3upf | 0BU | Polyprotein | / | 0.442 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.442 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.442 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.442 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.442 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
| 4jl6 | ADP | Adenylate kinase | / | 0.442 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4mpn | PV0 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.442 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.442 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
| 4zca | ADP | Kinesin-like protein KIF11 | / | 0.442 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.442 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 1efa | NPF | Lactose operon repressor | / | 0.441 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.441 | |
| 1sus | SAH | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.441 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.441 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.441 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.441 | |
| 2pch | SAH | Diphthine synthase | / | 0.441 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.441 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.441 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3da1 | FAD | Glycerol-3-phosphate dehydrogenase | / | 0.441 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.441 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.441 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3lf0 | ATP | Nitrogen regulatory protein P-II | / | 0.441 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.441 | |
| 3sa0 | NRA | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.441 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 4bhz | Z0B | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 4djq | M86 | Pol polyprotein | / | 0.441 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 4ksh | HTT | DNA gyrase subunit B | / | 0.441 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.441 | |
| 4xzn | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.441 | |
| 9hvp | 0E9 | Gag-Pol polyprotein | / | 0.441 | |
| 1g6c | IFP | Thiamine-phosphate synthase | / | 0.440 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1tkg | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1ytm | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.440 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.440 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.440 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3bnk | FMN | Flavoredoxin | / | 0.440 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.440 | |
| 3g6w | GTP | Uracil phosphoribosyltransferase | 2.4.2.9 | 0.440 | |
| 3gg1 | C2E | Uncharacterized protein | / | 0.440 | |
| 3mws | 017 | Pol protein | / | 0.440 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.440 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.440 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.440 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.440 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.440 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.440 |