Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 1.000 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.647 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.636 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.634 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.632 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.619 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.608 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.607 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.604 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.600 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.599 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.598 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.588 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.585 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.585 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.582 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.575 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.575 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.574 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.573 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.573 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.567 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.566 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.565 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.563 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.561 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.559 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.559 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.555 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.553 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.552 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.552 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.550 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.549 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.549 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.546 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.539 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.537 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.535 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.531 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.529 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.529 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.529 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.528 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.526 | |
| 2xiy | XIY | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.522 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.519 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.519 | |
| 3umw | 596 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.517 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.514 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.514 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.514 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.510 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.509 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.508 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.502 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.498 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.497 | |
| 4gw8 | 3RA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.495 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.493 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.492 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.489 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.488 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.487 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.485 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.484 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.483 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.480 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.480 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.479 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.478 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.478 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.478 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.478 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.477 | |
| 2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 2xiz | XIZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.476 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.476 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.476 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.476 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.475 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.475 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.475 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.475 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.474 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.474 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.474 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.474 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.473 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.473 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.472 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.472 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.472 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.472 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.470 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.470 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.470 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.469 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.469 | |
| 4i0t | 1B6 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.469 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.468 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.468 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.468 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.467 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.467 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.467 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.466 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.466 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.466 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.466 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.465 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.465 | |
| 2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.463 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.463 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 3blr | CPB | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.462 | |
| 3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.462 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.461 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.461 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.460 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 3vew | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.460 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.460 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.459 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.459 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.459 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.459 | |
| 5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.459 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.458 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.458 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.458 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.457 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.457 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.457 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.457 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.457 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.456 | |
| 3du8 | 553 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.456 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.455 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.455 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.455 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.454 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.454 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.454 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.454 | |
| 3lit | E15 | Protease | / | 0.454 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.454 | |
| 1t1s | CBQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.453 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.453 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 3qzg | X67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.453 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.453 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.453 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.452 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.452 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.452 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.452 | |
| 3sd0 | TSK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.452 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.452 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.452 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3q3b | 55E | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.451 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.451 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.451 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.450 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.450 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.450 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.450 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.450 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.450 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.449 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.449 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.449 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.449 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.449 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.448 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.448 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.448 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.448 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.448 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.447 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.447 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.447 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.447 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.446 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1jkl | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3liq | E14 | Protease | / | 0.445 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3rqj | Y2B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4j6i | 1JV | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.444 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.444 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3so9 | 017 | Pol protein | / | 0.444 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.443 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.443 | |
| 3o96 | IQO | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.443 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.443 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.443 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.441 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 3r34 | COA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.441 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.441 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.440 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.440 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.440 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.440 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.440 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 |