Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3r6xX84Cyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3r6xX84Cyclin-dependent kinase 22.7.11.221.000
3qxoX65Cyclin-dependent kinase 22.7.11.220.767
3roy22ZCyclin-dependent kinase 22.7.11.220.733
3raiX85Cyclin-dependent kinase 22.7.11.220.727
3r1qX75Cyclin-dependent kinase 22.7.11.220.704
3r28XA0Cyclin-dependent kinase 22.7.11.220.688
3rm719ZCyclin-dependent kinase 22.7.11.220.688
3qwkX62Cyclin-dependent kinase 22.7.11.220.648
3qx2X63Cyclin-dependent kinase 22.7.11.220.647
3r7vZ02Cyclin-dependent kinase 22.7.11.220.646
3r73X87Cyclin-dependent kinase 22.7.11.220.621
3lfnA27Cyclin-dependent kinase 22.7.11.220.616
3qwjX6ACyclin-dependent kinase 22.7.11.220.616
2r64740Cyclin-dependent kinase 22.7.11.220.612
3qzgX67Cyclin-dependent kinase 22.7.11.220.608
3qqfX07Cyclin-dependent kinase 22.7.11.220.606
1ckpPVBCyclin-dependent kinase 22.7.11.220.602
3r8vZ62Cyclin-dependent kinase 22.7.11.220.599
3qu0X40Cyclin-dependent kinase 22.7.11.220.598
3qzhX69Cyclin-dependent kinase 22.7.11.220.598
4lyn1YGCyclin-dependent kinase 22.7.11.220.595
1v1k3FPCyclin-dependent kinase 22.7.11.220.594
4fki09KCyclin-dependent kinase 22.7.11.220.593
3s0o50ZCyclin-dependent kinase 22.7.11.220.589
3sqq99ZCyclin-dependent kinase 22.7.11.220.589
3r8lZ30Cyclin-dependent kinase 22.7.11.220.588
1g5sI17Cyclin-dependent kinase 22.7.11.220.586
3rpo24ZCyclin-dependent kinase 22.7.11.220.586
4erwSTUCyclin-dependent kinase 22.7.11.220.585
1pxmCK5Cyclin-dependent kinase 22.7.11.220.583
3ddpRC8Cyclin-dependent kinase 22.7.11.220.583
1ke6LS2Cyclin-dependent kinase 22.7.11.220.581
3qtzX42Cyclin-dependent kinase 22.7.11.220.581
3r1sX73Cyclin-dependent kinase 22.7.11.220.581
3iggEFQCyclin-dependent kinase 22.7.11.220.580
3r9dX6BCyclin-dependent kinase 22.7.11.220.580
2c6o4SPCyclin-dependent kinase 22.7.11.220.579
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.575
3r7eX88Cyclin-dependent kinase 22.7.11.220.575
3s2pPMUCyclin-dependent kinase 22.7.11.220.575
3rjc06ZCyclin-dependent kinase 22.7.11.220.573
3rm618ZCyclin-dependent kinase 22.7.11.220.573
3rni21ZCyclin-dependent kinase 22.7.11.220.573
4ez30S0Cyclin-dependent kinase 22.7.11.220.572
2fvdLIACyclin-dependent kinase 22.7.11.220.568
3qtxX43Cyclin-dependent kinase 22.7.11.220.568
2btrU73Cyclin-dependent kinase 22.7.11.220.567
3ezrEZRCyclin-dependent kinase 22.7.11.220.567
3r71X86Cyclin-dependent kinase 22.7.11.220.567
1pxkCK3Cyclin-dependent kinase 22.7.11.220.566
3qtuX44Cyclin-dependent kinase 22.7.11.220.564
3r7yZ04Cyclin-dependent kinase 22.7.11.220.564
4ek610KCyclin-dependent kinase 22.7.11.220.564
1fvt106Cyclin-dependent kinase 22.7.11.220.563
2a0cCK9Cyclin-dependent kinase 22.7.11.220.559
3s1h56ZCyclin-dependent kinase 22.7.11.220.559
2btsU32Cyclin-dependent kinase 22.7.11.220.558
3ddqRRCCyclin-dependent kinase 22.7.11.220.556
3r7iX9ICyclin-dependent kinase 22.7.11.220.556
3rpv26ZCyclin-dependent kinase 22.7.11.220.556
1h1r6CPCyclin-dependent kinase 22.7.11.220.555
3r1yX76Cyclin-dependent kinase 22.7.11.220.554
3ti1B49Cyclin-dependent kinase 22.7.11.220.553
3rk708ZCyclin-dependent kinase 22.7.11.220.552
3rkb12ZCyclin-dependent kinase 22.7.11.220.552
4eor4SPCyclin-dependent kinase 22.7.11.220.551
3r83Z14Cyclin-dependent kinase 22.7.11.220.550
3rk909ZCyclin-dependent kinase 22.7.11.220.550
4fkq42KCyclin-dependent kinase 22.7.11.220.550
1gih1PUCyclin-dependent kinase 22.7.11.220.549
1h1s4SPCyclin-dependent kinase 22.7.11.220.549
1oguST8Cyclin-dependent kinase 22.7.11.220.548
1p2a5BNCyclin-dependent kinase 22.7.11.220.548
1ke9LS5Cyclin-dependent kinase 22.7.11.220.546
1oi9N20Cyclin-dependent kinase 22.7.11.220.546
1w0xOLOCyclin-dependent kinase 22.7.11.220.546
2b55D31Cyclin-dependent kinase 22.7.11.220.546
4ek816KCyclin-dependent kinase 22.7.11.220.546
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.545
2iw94SPCyclin-dependent kinase 22.7.11.220.545
2duv371Cyclin-dependent kinase 22.7.11.220.543
2r3lSCWCyclin-dependent kinase 22.7.11.220.543
2vu3LZECyclin-dependent kinase 22.7.11.220.543
2w05FRTCyclin-dependent kinase 22.7.11.220.542
3ezvEZVCyclin-dependent kinase 22.7.11.220.542
1di8DTQCyclin-dependent kinase 22.7.11.220.541
3rak03ZCyclin-dependent kinase 22.7.11.220.541
3qruX19Cyclin-dependent kinase 22.7.11.220.540
3s00Z60Cyclin-dependent kinase 22.7.11.220.540
4fkr45KCyclin-dependent kinase 22.7.11.220.540
1gii1PUCyclin-dependent kinase 22.7.11.220.539
2w06FRVCyclin-dependent kinase 22.7.11.220.539
3unk0BYCyclin-dependent kinase 22.7.11.220.539
4kd11QKCyclin-dependent kinase 22.7.11.220.539
1w8cN69Cyclin-dependent kinase 22.7.11.220.538
2a4lRRCCyclin-dependent kinase 22.7.11.220.538
1oiqHDUCyclin-dependent kinase 22.7.11.220.537
1vyw292Cyclin-dependent kinase 22.7.11.220.537
2w1hL0FCyclin-dependent kinase 22.7.11.220.537
3r9hZ67Cyclin-dependent kinase 22.7.11.220.537
2r3kSCQCyclin-dependent kinase 22.7.11.220.536
3r7uX96Cyclin-dependent kinase 22.7.11.220.536
3qqkX02Cyclin-dependent kinase 22.7.11.220.535
1ke7LS3Cyclin-dependent kinase 22.7.11.220.534
1oitHDTCyclin-dependent kinase 22.7.11.220.534
2b52D42Cyclin-dependent kinase 22.7.11.220.534
2iw84SPCyclin-dependent kinase 22.7.11.220.534
3rk507ZCyclin-dependent kinase 22.7.11.220.534
1urwI1PCyclin-dependent kinase 22.7.11.220.533
1vyzN5BCyclin-dependent kinase 22.7.11.220.533
1ykr628Cyclin-dependent kinase 22.7.11.220.532
3r8pZ46Cyclin-dependent kinase 22.7.11.220.531
1ke5LS1Cyclin-dependent kinase 22.7.11.220.530
3ral04ZCyclin-dependent kinase 22.7.11.220.530
4bcmT7ZCyclin-dependent kinase 22.7.11.220.528
1oiuN76Cyclin-dependent kinase 22.7.11.220.527
4bcpT3CCyclin-dependent kinase 22.7.11.220.527
4fkpLS5Cyclin-dependent kinase 22.7.11.220.527
3lfqA28Cyclin-dependent kinase 22.7.11.220.526
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.525
2xmyCDKCyclin-dependent kinase 22.7.11.220.525
4fkj11KCyclin-dependent kinase 22.7.11.220.525
3wblPDYCyclin-dependent kinase 22.7.11.220.524
2r3o2SCCyclin-dependent kinase 22.7.11.220.523
2uzoC62Cyclin-dependent kinase 22.7.11.220.523
3rahO1ZCyclin-dependent kinase 22.7.11.220.522
4bgh3I6Cyclin-dependent kinase 22.7.11.220.522
2uznC96Cyclin-dependent kinase 22.7.11.220.521
3ig7EFPCyclin-dependent kinase 22.7.11.220.521
2r3p3SCCyclin-dependent kinase 22.7.11.220.518
3tiz3TICyclin-dependent kinase 22.7.11.220.518
2c69CT8Cyclin-dependent kinase 22.7.11.220.517
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.517
1h0w207Cyclin-dependent kinase 22.7.11.220.516
3ql8X01Cyclin-dependent kinase 22.7.11.220.516
3qqlX03Cyclin-dependent kinase 22.7.11.220.516
3unj0BXCyclin-dependent kinase 22.7.11.220.516
4acm7YGCyclin-dependent kinase 22.7.11.220.516
1ke8LS4Cyclin-dependent kinase 22.7.11.220.515
2bhhRYUCyclin-dependent kinase 22.7.11.220.515
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.515
2vtsLZCCyclin-dependent kinase 22.7.11.220.515
3qrtX14Cyclin-dependent kinase 22.7.11.220.515
1pxlCK4Cyclin-dependent kinase 22.7.11.220.514
3qqhX0ACyclin-dependent kinase 22.7.11.220.514
1r78FMDCyclin-dependent kinase 22.7.11.220.513
2r3r6SCCyclin-dependent kinase 22.7.11.220.513
3lfsA07Cyclin-dependent kinase 22.7.11.220.513
1oiyN41Cyclin-dependent kinase 22.7.11.220.512
3qziX72Cyclin-dependent kinase 22.7.11.220.512
2c4g514Cyclin-dependent kinase 22.7.11.220.511
2i40BLZCyclin-dependent kinase 22.7.11.220.511
2r3gSC9Cyclin-dependent kinase 22.7.11.220.511
3sw418KCyclin-dependent kinase 22.7.11.220.511
1y91CT9Cyclin-dependent kinase 22.7.11.220.510
2vv9IM9Cyclin-dependent kinase 22.7.11.220.510
3pj8404Cyclin-dependent kinase 22.7.11.220.509
3my5RFZCyclin-dependent kinase 22.7.11.220.508
3r8uZ31Cyclin-dependent kinase 22.7.11.220.508
3qxpX64Cyclin-dependent kinase 22.7.11.220.506
3rmf20ZCyclin-dependent kinase 22.7.11.220.506
1pkdUCNCyclin-dependent kinase 22.7.11.220.505
2j9mPY8Cyclin-dependent kinase 22.7.11.220.505
3qtrX36Cyclin-dependent kinase 22.7.11.220.505
4bcnT9NCyclin-dependent kinase 22.7.11.220.504
1e9hINRCyclin-dependent kinase 22.7.11.220.503
1h1pCMGCyclin-dependent kinase 22.7.11.220.503
2wpa889Cyclin-dependent kinase 22.7.11.220.503
4fko20KCyclin-dependent kinase 22.7.11.220.503
2r3iSCFCyclin-dependent kinase 22.7.11.220.502
3rpr25ZCyclin-dependent kinase 22.7.11.220.502
4eok4SPCyclin-dependent kinase 22.7.11.220.501
1gij2PUCyclin-dependent kinase 22.7.11.220.500
4eon1ROCyclin-dependent kinase 22.7.11.220.500
1unlRRCCyclin-dependent-like kinase 52.7.11.10.499
2b54D05Cyclin-dependent kinase 22.7.11.220.499
2c6tDT5Cyclin-dependent kinase 22.7.11.220.499
1h1q2A6Cyclin-dependent kinase 22.7.11.220.498
1oirHDYCyclin-dependent kinase 22.7.11.220.498
2c5nCK8Cyclin-dependent kinase 22.7.11.220.498
3le62BZCyclin-dependent kinase 22.7.11.220.496
4fkv61KCyclin-dependent kinase 22.7.11.220.496
4fkg4CKCyclin-dependent kinase 22.7.11.220.495
4fkt48KCyclin-dependent kinase 22.7.11.220.495
2x1nX1NCyclin-dependent kinase 22.7.11.220.494
4bcoT6QCyclin-dependent kinase 22.7.11.220.494
1pyePM1Cyclin-dependent kinase 22.7.11.220.493
3pxyJWSCyclin-dependent kinase 22.7.11.220.493
2c6mDT5Cyclin-dependent kinase 22.7.11.220.491
3sw719KCyclin-dependent kinase 22.7.11.220.491
4cfnJYMCyclin-dependent kinase 22.7.11.220.490
4fx360KCyclin-dependent kinase 22.7.11.220.490
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.490
2c6iDT1Cyclin-dependent kinase 22.7.11.220.489
2c6lDT4Cyclin-dependent kinase 22.7.11.220.489
4fks46KCyclin-dependent kinase 22.7.11.220.489
1aq1STUCyclin-dependent kinase 22.7.11.220.488
2w17I19Cyclin-dependent kinase 22.7.11.220.488
3rzb02ZCyclin-dependent kinase 22.7.11.220.488
4qmpDKISerine/threonine-protein kinase 242.7.11.10.488
3py0SU9Cyclin-dependent kinase 22.7.11.220.487
3qtqX35Cyclin-dependent kinase 22.7.11.220.487
3qtwX3ACyclin-dependent kinase 22.7.11.220.487
1pxpCK8Cyclin-dependent kinase 22.7.11.220.486
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.486
3dogNNNCyclin-dependent kinase 22.7.11.220.486
3r8zZ63Cyclin-dependent kinase 22.7.11.220.486
4eol1ROCyclin-dependent kinase 22.7.11.220.486
2wxvWXVCyclin-dependent kinase 22.7.11.220.484
3rpy27ZCyclin-dependent kinase 22.7.11.220.484
3uli1N3Cyclin-dependent kinase 22.7.11.220.484
4eos1ROCyclin-dependent kinase 22.7.11.220.484
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.483
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.483
2r3jSCJCyclin-dependent kinase 22.7.11.220.482
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.482
3ggfGVDSerine/threonine-protein kinase 26/0.481
4fkw62KCyclin-dependent kinase 22.7.11.220.481
3r9nZ68Cyclin-dependent kinase 22.7.11.220.480
2uzlC94Cyclin-dependent kinase 22.7.11.220.478
2bheBRYCyclin-dependent kinase 22.7.11.220.477
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.477
3fz1B98Cyclin-dependent kinase 22.7.11.220.476
2uzdC85Cyclin-dependent kinase 22.7.11.220.475
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.475
1h0vUN4Cyclin-dependent kinase 22.7.11.220.474
2c5yMTWCyclin-dependent kinase 22.7.11.220.474
2vthLZ2Cyclin-dependent kinase 22.7.11.220.474
4bcqTJFCyclin-dependent kinase 22.7.11.220.474
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.474
2xnbY8LCyclin-dependent kinase 22.7.11.220.471
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.471
2wotZZGTGF-beta receptor type-12.7.11.300.470
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2r3fSC8Cyclin-dependent kinase 22.7.11.220.466
2vttLZDCyclin-dependent kinase 22.7.11.220.466
1b39ATPCyclin-dependent kinase 22.7.11.220.465
1dm2HMDCyclin-dependent kinase 22.7.11.220.464
1pxoCK7Cyclin-dependent kinase 22.7.11.220.464
3nup3NUCyclin-dependent kinase 62.7.11.220.464
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.463
2r3mSCXCyclin-dependent kinase 22.7.11.220.462
2cchATPCyclin-dependent kinase 22.7.11.220.461
3qtsX46Cyclin-dependent kinase 22.7.11.220.461
3qzfX66Cyclin-dependent kinase 22.7.11.220.461
3r9oZ71Cyclin-dependent kinase 22.7.11.220.461
4fv9E71Mitogen-activated protein kinase 12.7.11.240.461
2uzbC75Cyclin-dependent kinase 22.7.11.220.460
1e1xNW1Cyclin-dependent kinase 22.7.11.220.459
4eomATPCyclin-dependent kinase 22.7.11.220.459
2wihP48Cyclin-dependent kinase 22.7.11.220.458
1y8yCT7Cyclin-dependent kinase 22.7.11.220.457
3sheI85MAP kinase-activated protein kinase 32.7.11.10.457
3tnwF18Cyclin-dependent kinase 22.7.11.220.457
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.455
1b38ATPCyclin-dependent kinase 22.7.11.220.453
2uzeC95Cyclin-dependent kinase 22.7.11.220.453
4eoi1ROCyclin-dependent kinase 22.7.11.220.453
1e1vCMGCyclin-dependent kinase 22.7.11.220.452
1fvv107Cyclin-dependent kinase 22.7.11.220.450
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.450
4eop1ROCyclin-dependent kinase 22.7.11.220.450
2eufLQQCyclin-dependent kinase 62.7.11.220.449
2r3q5SCCyclin-dependent kinase 22.7.11.220.449
2vtqLZACyclin-dependent kinase 22.7.11.220.449
3bhtMFRCyclin-dependent kinase 22.7.11.220.449
1v0pPVBCell division control protein 2 homolog2.7.11.220.448
2csnCKICasein kinase I homolog 12.7.11.10.448
1gz8MBPCyclin-dependent kinase 22.7.11.220.447
1v0oINRCell division control protein 2 homolog2.7.11.220.447
2b53D23Cyclin-dependent kinase 22.7.11.220.447
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.447
2pvnP63Casein kinase II subunit alpha2.7.11.10.446
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.446
3nwxKVSGag-Pol polyprotein3.4.23.160.446
4fv8E63Mitogen-activated protein kinase 12.7.11.240.446
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.445
1xjdSTUProtein kinase C theta type2.7.11.130.444
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.444
4ogrADNCyclin-dependent kinase 92.7.11.220.444
2bkzSBCCyclin-dependent kinase 22.7.11.220.443
4ivb1J5Tyrosine-protein kinase JAK1/0.443
4ivd15TTyrosine-protein kinase JAK1/0.442
1k6vXN2Gag-Pol polyprotein3.4.23.160.441
5aniES4Cyclin-dependent kinase 22.7.11.220.441
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.440
3qx4X4BCyclin-dependent kinase 22.7.11.220.440
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.440
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.440