Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 1.000 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.620 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.614 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.585 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.583 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.569 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.563 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.560 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.558 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.557 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.555 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.554 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.549 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.543 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.539 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.525 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.524 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.521 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.507 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.504 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.503 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.503 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.493 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.487 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.485 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.484 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.483 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.480 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.480 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.478 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.478 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.477 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.477 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.475 | |
| 4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.475 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.471 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.471 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.470 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.470 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.470 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.470 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.469 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.469 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.468 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.468 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.467 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.467 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.467 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.466 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.466 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.465 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.465 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 1r2j | FAD | FkbI | / | 0.464 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.464 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.463 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.463 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.463 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.462 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.462 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.462 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.461 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.461 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 3q9w | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.460 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.460 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.460 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.459 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.459 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.459 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.459 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4l44 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.459 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.459 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.458 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.458 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.458 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.458 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.458 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.457 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.457 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.457 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.457 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.457 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.457 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.457 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.457 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.457 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.457 | |
| 4ivd | 15T | Tyrosine-protein kinase JAK1 | / | 0.457 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.456 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.456 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.456 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.455 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.455 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.455 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 5dp2 | NAP | CurF | / | 0.455 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.454 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.454 | |
| 4jpe | 1M7 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.454 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.453 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.453 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.453 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.453 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.453 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.452 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.452 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.452 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.452 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.451 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.451 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.451 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.451 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.451 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1sre | HAB | Streptavidin | / | 0.450 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.450 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.450 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.450 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.450 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.449 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.449 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.449 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.449 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.449 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.449 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.449 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.449 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 2f2u | M77 | Rho-associated protein kinase 2 | 2.7.11.1 | 0.448 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.448 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.448 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.448 | |
| 5a3c | NAD | SIR2 family protein | / | 0.448 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.448 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.447 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.447 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.447 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.447 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.447 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.447 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.446 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 2g1p | SAH | DNA adenine methylase | 2.1.1.72 | 0.446 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.446 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.446 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.446 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 5im3 | DTP | Ribonucleoside-diphosphate reductase | / | 0.446 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.445 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.445 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.445 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.445 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.445 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 3rdq | DTB | Streptavidin | / | 0.445 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.445 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.445 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.444 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.444 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4l8u | 9AZ | Serum albumin | / | 0.444 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.443 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.443 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.443 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.443 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.443 | |
| 3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.443 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.443 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.443 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.442 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.442 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.442 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.442 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 2jjj | 0QS | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 2ohv | NHL | Glutamate racemase | / | 0.441 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.441 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.441 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.441 | |
| 1fwy | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.440 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.440 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.440 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.440 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.440 | |
| 3nz4 | TCA | Phenylalanine aminomutase (L-beta-phenylalanine forming) | / | 0.440 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.440 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.440 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.440 |