sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3gfd | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3gfd | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 1.000 | |
| 4ttc | FMN | Iodotyrosine deiodinase 1 | / | 0.615 | |
| 4ttb | FMN | Iodotyrosine deiodinase 1 | / | 0.586 | |
| 3to0 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.567 | |
| 3gh8 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.554 | |
| 3hj9 | FMN | Uncharacterized protein | / | 0.534 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.529 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.512 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.499 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.497 | |
| 3ge6 | FMN | Nitroreductase | / | 0.496 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.496 | |
| 1oon | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.493 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.493 | |
| 3pxv | FMN | Nitroreductase | / | 0.493 | |
| 3eof | FMN | Putative oxidase | / | 0.492 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.491 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.490 | |
| 4qly | FMN | Enone reductase CLA-ER | / | 0.489 | |
| 1yki | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.487 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.486 | |
| 3e39 | FMN | Nitroreductase | / | 0.485 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.485 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.484 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.483 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.482 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.482 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.481 | |
| 3x22 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.481 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.479 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.478 | |
| 1oo5 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.478 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.474 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.474 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.473 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.472 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.472 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.471 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.470 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.470 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.470 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.469 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.469 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.469 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.468 | |
| 2wzv | FMN | Nitroreductase NfnB | / | 0.468 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.468 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.467 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.466 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.466 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.465 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.465 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.465 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.464 | |
| 3koq | FMN | Putative nitroreductase | / | 0.464 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.464 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.464 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.464 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.464 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.463 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.463 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.463 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.463 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.463 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.463 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.462 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.461 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.460 | |
| 1ooq | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.460 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.460 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.460 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.460 | |
| 2isj | FMN | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.459 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.458 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.458 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.457 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.457 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.456 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.456 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.455 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.455 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.455 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.455 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.455 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.455 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.455 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.454 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.454 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.454 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.453 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 3a3g | DLZ | Lumazine protein | / | 0.453 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.453 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.453 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.453 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.452 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.452 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.452 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4a5l | NDP | Thioredoxin reductase | / | 0.452 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.452 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.451 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.451 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.451 | |
| 2wzw | FMN | Nitroreductase NfnB | / | 0.451 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.451 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.451 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.450 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.449 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.449 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 2e15 | SAH | Diphthine synthase | / | 0.449 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.449 | |
| 3lki | ATP | Fructokinase | / | 0.449 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.449 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.448 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.448 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.448 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.448 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.448 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.448 | |
| 4m99 | ACO | UDP-N-acetylgalactosaminyltransferase | / | 0.448 | |
| 4p5a | FAD | Flavin-dependent thymidylate synthase | / | 0.448 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.447 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3q8h | AO9 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.447 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.447 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.446 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.446 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.446 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.446 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.446 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.445 | |
| 2y4g | TIR | TamL | / | 0.445 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.445 | |
| 4blr | UTP | NTPase P4 | / | 0.445 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.444 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.444 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.444 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.444 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.444 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.443 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.443 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.443 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.443 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.443 | |
| 2q14 | ADP | Phosphohydrolase | / | 0.443 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.443 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.443 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.442 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.442 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.442 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 1ht0 | NAD | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.441 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.441 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.441 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.441 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.441 | |
| 3a5y | KAA | Elongation factor P--(R)-beta-lysine ligase | / | 0.441 | |
| 3bem | FMN | Putative NAD(P)H nitroreductase MhqN | 1 | 0.441 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.441 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.441 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.441 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.441 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.441 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.440 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3dvl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.440 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.440 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.440 |