sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3esy | FMN | Flavodoxin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3esy | FMN | Flavodoxin | / | 1.000 | |
| 3esz | FMN | Flavodoxin | / | 0.585 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.564 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.545 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.533 | |
| 3f6r | FMN | Flavodoxin | / | 0.531 | |
| 1czn | FMN | Flavodoxin | / | 0.528 | |
| 2v5u | FMN | Flavodoxin | / | 0.514 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.505 | |
| 1j9g | FMN | Flavodoxin | / | 0.502 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.500 | |
| 3n3a | FMN | Protein NrdI | / | 0.496 | |
| 3f6s | FMN | Flavodoxin | / | 0.495 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.495 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.489 | |
| 1fx1 | FMN | Flavodoxin | / | 0.488 | |
| 1ofv | FMN | Flavodoxin | / | 0.488 | |
| 1akw | FMN | Flavodoxin | / | 0.485 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.484 | |
| 1j8q | FMN | Flavodoxin | / | 0.483 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.482 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.482 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.482 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.481 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.478 | |
| 2v5v | FMN | Flavodoxin | / | 0.478 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.478 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.478 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.477 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.476 | |
| 4oxx | FMN | Cindoxin | / | 0.476 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.474 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 1azl | FMN | Flavodoxin | / | 0.473 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.472 | |
| 3kap | FMN | Flavodoxin | / | 0.472 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.472 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1xyy | FMN | Flavodoxin | / | 0.471 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.470 | |
| 3hr4 | FMN | Nitric oxide synthase, inducible | 1.14.13.39 | 0.470 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.470 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.470 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1bdu | DUR | Thymidylate synthase | / | 0.469 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.469 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1bu5 | RBF | Flavodoxin | / | 0.468 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.468 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.468 | |
| 3v2u | ATP | Protein GAL3 | / | 0.468 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.467 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.467 | |
| 1xag | NAD | 3-dehydroquinate synthase | / | 0.466 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.466 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.466 | |
| 1aob | DDU | Thymidylate synthase | / | 0.465 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.465 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1c7f | FMN | Flavodoxin | / | 0.464 | |
| 1fml | RTL | Retinol dehydratase | / | 0.464 | |
| 3klb | FMN | Uncharacterized protein | / | 0.464 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 4fx2 | FMN | Flavodoxin | / | 0.462 | |
| 5xr8 | FMN | Cannabinoid receptor 1 | / | 0.462 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.461 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.461 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.461 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.461 | |
| 1c7o | PPG | Hemolysin | / | 0.460 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.460 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.460 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.460 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.459 | |
| 1aku | FMN | Flavodoxin | / | 0.458 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.458 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 0.458 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.458 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4n65 | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.458 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 5xra | FMN | Cannabinoid receptor 1 | / | 0.458 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3eku | CY9 | Actin-5C | / | 0.457 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.457 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.456 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3w5u | FAD | Ferredoxin | / | 0.456 | |
| 1akr | FMN | Flavodoxin | / | 0.455 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.455 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.455 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.455 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.455 | |
| 2fcr | FMN | Flavodoxin | / | 0.454 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.454 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.454 | |
| 1gaq | FAD | Ferredoxin | / | 0.453 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.452 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.452 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.452 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.452 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.452 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.452 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.452 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.452 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.451 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.451 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.451 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.451 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4h6p | FMN | Chromate reductase | / | 0.451 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3f90 | FMN | Flavodoxin | / | 0.450 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.450 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1wsb | FMN | Flavodoxin | / | 0.449 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.449 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.449 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.449 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.448 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.448 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.448 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.448 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.448 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.448 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.447 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.447 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.447 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1j9z | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.446 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.446 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.446 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 5f12 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.446 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3kaq | FMN | Flavodoxin | / | 0.445 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.445 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.445 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.444 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.444 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.444 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.444 | |
| 4j7h | TRH | PCZA361.3 | / | 0.444 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.443 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.443 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.442 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2v7u | SAM | 5'-fluoro-5'-deoxy-adenosine synthase | / | 0.442 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.442 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.442 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.442 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.442 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.441 | |
| 1yob | FMN | Flavodoxin 2 | / | 0.441 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.441 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.441 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.441 | |
| 3n39 | FMN | Protein NrdI | / | 0.441 | |
| 3n3b | FMN | Protein NrdI | / | 0.441 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.441 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.440 | |
| 1e2n | RCA | Thymidine kinase | / | 0.440 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.440 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1hzz | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.440 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.440 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.440 | |
| 2vet | UMP | Thymidylate synthase | / | 0.440 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.440 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.440 | |
| 4j8p | FMN | Flavodoxin | / | 0.440 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |