sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 1.000 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.591 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.588 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.569 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.557 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.557 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.555 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.553 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.552 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.549 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.543 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.542 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.542 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.540 | |
| 2d2i | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.537 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.537 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.535 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.534 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.533 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.533 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.532 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.530 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.529 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.529 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.529 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.528 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.528 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.527 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.525 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.520 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.520 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.519 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.516 | |
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.515 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.513 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.513 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.510 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.510 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.507 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.506 | |
| 3k2b | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.506 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.506 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.504 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.504 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.500 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.498 | |
| 1jn0 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.495 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.494 | |
| 1rm3 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.488 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.485 | |
| 3l4s | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.485 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.484 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.484 | |
| 1ihy | APR | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.482 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.480 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.479 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 3l0d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.478 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.478 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.477 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.477 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.475 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.474 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.473 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.472 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.472 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.472 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.472 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.472 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.471 | |
| 2cvu | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.469 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.468 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.468 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.468 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.467 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.467 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.467 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.467 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.465 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.465 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.464 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.463 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.463 | |
| 3o0o | GDP | Vitamin B12-dependent ribonucleotide reductase | / | 0.463 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.462 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.462 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.461 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.461 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.461 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.458 | |
| 3ieu | GDP | GTPase Era | / | 0.458 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.458 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.458 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.457 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.457 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.457 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.457 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.457 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.457 | |
| 2cvw | GDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.456 | |
| 3el0 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.455 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.455 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.455 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.455 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.454 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.454 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.454 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.454 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.454 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.454 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2ejz | SAH | Diphthine synthase | / | 0.453 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.453 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.453 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.452 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.452 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.451 | |
| 4hxy | NDP | Plm1 | / | 0.451 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.451 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.450 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.450 | |
| 2zja | ACP | ATP-dependent DNA helicase Hel308 | / | 0.450 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.450 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.450 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.450 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.449 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.449 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.449 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 5a3b | APR | SIR2 family protein | / | 0.448 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.448 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.447 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.447 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.447 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.447 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4y0k | NAP | AntE | / | 0.447 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.446 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.446 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.446 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.446 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 3tba | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.446 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.446 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.446 | |
| 4u7w | NDP | MxaA | / | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.445 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3gob | HXX | DdmC | / | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3smk | CW7 | 14-3-3 protein sigma | / | 0.445 | |
| 3u9e | COA | Lmo1369 protein | / | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.445 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.445 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.445 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.445 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.444 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 2e07 | SAH | Diphthine synthase | / | 0.444 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.444 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3s8c | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.444 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4qec | NAP | ElxO | / | 0.444 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.444 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.444 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.443 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 2o4c | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.443 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.443 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.443 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.443 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.443 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.443 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.443 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.443 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.442 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.441 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.441 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
| 4njs | G08 | Protease | / | 0.441 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.440 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.440 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 |