sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vea | HBN | Hut operon positive regulatory protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1vea | HBN | Hut operon positive regulatory protein | / | 1.000 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.512 | |
| 2pca | SAH | Diphthine synthase | / | 0.509 | |
| 2e08 | SAH | Diphthine synthase | / | 0.508 | |
| 2pch | SAH | Diphthine synthase | / | 0.499 | |
| 2p9d | SAH | Diphthine synthase | / | 0.497 | |
| 2owu | SAH | Diphthine synthase | / | 0.494 | |
| 2p5c | SAH | Diphthine synthase | / | 0.493 | |
| 2dxx | SAH | Diphthine synthase | / | 0.492 | |
| 2egl | SAH | Diphthine synthase | / | 0.492 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.492 | |
| 2e07 | SAH | Diphthine synthase | / | 0.490 | |
| 2ejj | SAH | Diphthine synthase | / | 0.490 | |
| 2dsi | SAH | Diphthine synthase | / | 0.489 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.489 | |
| 2owk | SAH | Diphthine synthase | / | 0.488 | |
| 2ejk | SAH | Diphthine synthase | / | 0.487 | |
| 2huv | SAH | Diphthine synthase | / | 0.486 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.486 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.486 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 2p5f | SAH | Diphthine synthase | / | 0.484 | |
| 2owg | SAH | Diphthine synthase | / | 0.483 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.483 | |
| 2eeq | SAH | Diphthine synthase | / | 0.482 | |
| 1vce | SAH | Diphthine synthase | / | 0.481 | |
| 2dsh | SAH | Diphthine synthase | / | 0.481 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.481 | |
| 2p6k | SAH | Diphthine synthase | / | 0.481 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.481 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 1wng | SAH | Diphthine synthase | / | 0.479 | |
| 2e4n | SAH | Diphthine synthase | / | 0.479 | |
| 2e7r | SAH | Diphthine synthase | / | 0.479 | |
| 2hut | SAH | Diphthine synthase | / | 0.479 | |
| 3u9e | COA | Lmo1369 protein | / | 0.479 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.478 | |
| 2el0 | SAH | Diphthine synthase | / | 0.478 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.478 | |
| 2p2x | SAH | Diphthine synthase | / | 0.477 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.477 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.476 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.476 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.476 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
| 1mma | ADP | Myosin-2 heavy chain | / | 0.475 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.475 | |
| 2z6r | SAH | Diphthine synthase | / | 0.475 | |
| 2egs | SAH | Diphthine synthase | / | 0.474 | |
| 2huq | SAH | Diphthine synthase | / | 0.474 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2e8q | SAH | Diphthine synthase | / | 0.472 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.472 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.471 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.471 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.471 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.471 | |
| 2dek | SAH | Diphthine synthase | / | 0.470 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.470 | |
| 2owv | SAH | Diphthine synthase | / | 0.470 | |
| 2p6i | SAH | Diphthine synthase | / | 0.470 | |
| 2zfa | FMN | Lactate oxidase | / | 0.470 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.469 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2yer | TQ1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.468 | |
| 2eka | SAH | Diphthine synthase | / | 0.468 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.468 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 3ti1 | B49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2ele | SAH | Diphthine synthase | / | 0.466 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.466 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.466 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.466 | |
| 2egb | SAH | Diphthine synthase | / | 0.465 | |
| 2en5 | SAH | Diphthine synthase | / | 0.465 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.465 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.465 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 2emu | SAH | Diphthine synthase | / | 0.464 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.464 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.464 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.464 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.463 | |
| 2dxv | SAH | Diphthine synthase | / | 0.463 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.462 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.462 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.461 | |
| 1y8y | CT7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.461 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 5fbh | TCR | Extracellular calcium-sensing receptor | / | 0.461 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.460 | |
| 2e15 | SAH | Diphthine synthase | / | 0.460 | |
| 2eni | SAH | Diphthine synthase | / | 0.460 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.460 | |
| 2e17 | SAH | Diphthine synthase | / | 0.459 | |
| 2el3 | SAH | Diphthine synthase | / | 0.459 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 3lxk | MI1 | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.459 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.459 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.459 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.459 | |
| 4fk6 | 0UJ | Tyrosine-protein kinase JAK1 | / | 0.459 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.459 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.458 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2emr | SAH | Diphthine synthase | / | 0.458 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.458 | |
| 2p6l | SAH | Diphthine synthase | / | 0.458 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.458 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 2e16 | SAH | Diphthine synthase | / | 0.457 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.457 | |
| 2pci | SAH | Diphthine synthase | / | 0.457 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.457 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.457 | |
| 3nbv | ANP | Ketohexokinase | / | 0.457 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.457 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2hux | SAH | Diphthine synthase | / | 0.456 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.456 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.456 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2dxw | SAH | Diphthine synthase | / | 0.455 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.455 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.455 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.455 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.455 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.454 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.454 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.454 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 4jpc | 1M6 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 1gz8 | MBP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.453 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.453 | |
| 2pcm | SAH | Diphthine synthase | / | 0.453 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.453 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.453 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.453 | |
| 4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.453 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.452 | |
| 2e8r | SAH | Diphthine synthase | / | 0.452 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.452 | |
| 3ayg | HQO | Nitric oxide reductase | / | 0.452 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.452 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4a9u | A9U | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.452 | |
| 4e4l | 0NH | Tyrosine-protein kinase JAK1 | / | 0.452 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.451 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2r3j | SCJ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.451 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.451 | |
| 4ix4 | ADP | Uncharacterized protein | / | 0.451 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.451 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2ejz | SAH | Diphthine synthase | / | 0.450 | |
| 2vtp | LZ9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.449 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.449 | |
| 2ehl | SAH | Diphthine synthase | / | 0.449 | |
| 2jkk | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.449 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.449 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.449 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.449 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.449 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.449 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.449 | |
| 4e20 | 0MY | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4zhq | ACP | Tubulin tyrosine ligase | / | 0.449 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.448 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.448 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.448 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.448 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.448 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4g6o | E28 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.448 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 2e8h | SAH | Diphthine synthase | / | 0.447 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.447 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.447 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.447 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.447 | |
| 4dt9 | GMP | APH(2'')-Id | / | 0.447 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.447 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.447 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.446 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.446 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.446 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.446 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3qzi | X72 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 4cef | D0T | Integrase | / | 0.446 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.446 | |
| 4ivd | 15T | Tyrosine-protein kinase JAK1 | / | 0.446 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1pxk | CK3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.445 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.445 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.445 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2nr4 | FMN | Conserved protein | / | 0.445 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.445 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.445 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4c61 | LMM | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4e1z | 0MX | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.445 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.445 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.445 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.445 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 1os1 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.444 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.444 | |
| 2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.444 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.444 | |
| 2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2uzn | C96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.444 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.444 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4jpe | 1M7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.444 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 1g28 | FMN | PHY3 | / | 0.443 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.443 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.443 | |
| 2pck | SAH | Diphthine synthase | / | 0.443 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.443 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.443 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.443 | |
| 4k6z | 1Q3 | Tyrosine-protein kinase JAK1 | / | 0.443 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.443 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.442 | |
| 1pxo | CK7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.442 | |
| 2p6d | SAH | Diphthine synthase | / | 0.442 | |
| 2pcg | SAH | Diphthine synthase | / | 0.442 | |
| 2vh0 | GSI | Coagulation factor X | 3.4.21.6 | 0.442 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.442 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.442 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3zdi | UGJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.442 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.442 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 4rje | FNR | Lactate oxidase | / | 0.442 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.441 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1qp8 | NDP | 2-hydroxyacid dehydrogenase | / | 0.441 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.441 | |
| 2eld | SAH | Diphthine synthase | / | 0.441 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.441 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.441 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 5ax3 | 5ID | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.440 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.440 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2exm | ZIP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.440 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.440 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.440 | |
| 3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.440 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.440 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.440 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4e6q | 0NV | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.440 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.440 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.440 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.440 |