sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1odi | ADN | Purine nucleoside phosphorylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1odi | ADN | Purine nucleoside phosphorylase | / | 1.000 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.726 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.573 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.569 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.552 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.546 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.545 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.538 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.533 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.525 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.517 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.513 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.509 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.504 | |
| 3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 0.495 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.494 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.492 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.487 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.486 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.486 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.482 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.482 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.478 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.475 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.474 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.474 | |
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.472 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.471 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.471 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.467 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.466 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.464 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.462 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.462 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.460 | |
| 3c74 | ANU | Uridine phosphorylase | 2.4.2.3 | 0.458 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.458 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.456 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.456 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.454 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1q1g | MTI | Purine nucleoside phosphorylase | / | 0.449 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1a69 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.448 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.448 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.447 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.446 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.445 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.445 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.445 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 4e2y | JHZ | Methyltransferase | / | 0.444 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.444 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.442 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.441 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2hwu | URI | Uridine phosphorylase | 2.4.2.3 | 0.440 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.440 | |
| 3arv | SAU | Chitinase A | / | 0.440 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.440 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.440 |