sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 1.311 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 1.272 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 1.041 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 1.020 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 1.008 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 1.008 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 1.002 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 1.001 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.986 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.975 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.958 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.949 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.934 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.933 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.933 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.932 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.929 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.927 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.926 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.920 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.907 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.906 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.906 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.905 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.904 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.903 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.900 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.899 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.891 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.889 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.888 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.886 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.886 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.884 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.883 | |
| 4kwh | NAP | Reductase homolog | / | 0.881 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.880 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.879 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.878 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.877 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.875 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.873 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.873 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.872 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.871 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.870 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.865 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.856 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.856 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.855 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.853 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.850 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.848 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.848 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.848 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.846 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.846 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.843 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.843 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.840 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.838 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.836 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.835 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.833 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.833 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.832 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.831 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.830 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.830 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.828 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.827 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.827 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.826 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.825 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.825 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.824 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.824 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.824 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.821 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.817 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.814 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.814 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.811 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.805 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.804 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.804 | |
| 4qec | NAP | ElxO | / | 0.803 | |
| 4hxy | NDP | Plm1 | / | 0.802 | |
| 4qed | NAP | ElxO | / | 0.802 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.801 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.801 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.800 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.798 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.797 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.794 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.793 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.792 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.792 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.789 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.788 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.787 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.786 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.784 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.784 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.782 | |
| 3sju | NDP | Keto reductase | / | 0.780 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.780 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.777 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.776 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.775 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.774 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.773 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.773 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.773 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.773 | |
| 4u7w | NDP | MxaA | / | 0.773 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.771 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.769 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.769 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.768 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.768 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.766 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.765 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.765 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.764 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.762 | |
| 1iy8 | NAD | Levodione reductase | / | 0.761 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.760 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.759 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.758 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.758 | |
| 4clo | NAP | Pteridine reductase | / | 0.756 | |
| 3bmo | NAP | Pteridine reductase | / | 0.755 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.755 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.755 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.754 | |
| 3mje | NDP | AmphB | / | 0.753 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.753 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.750 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.750 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.750 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.749 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.748 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.747 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.747 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.746 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.746 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.744 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.744 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.743 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.741 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.741 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.740 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.740 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.740 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.740 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.738 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.737 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.737 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.736 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.736 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.736 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.736 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.736 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.735 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.733 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.732 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.732 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.731 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.731 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.730 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.729 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.728 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.727 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.727 | |
| 1sny | NAP | LD36273p | / | 0.726 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.726 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.726 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.725 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.724 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.724 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.720 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.720 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.719 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.718 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.718 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.718 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.717 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.716 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.712 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.712 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.711 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.710 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.709 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.709 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.706 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.705 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.704 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.704 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.703 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.701 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.701 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.701 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.700 | |
| 3qj4 | FAD | Renalase | / | 0.698 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.698 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.697 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.696 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.696 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.695 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.695 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.694 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.694 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.693 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.692 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.692 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.692 | |
| 4icy | FAD | PgaE | / | 0.691 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.690 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.690 | |
| 3uce | NDP | Dehydrogenase | / | 0.690 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.688 | |
| 5d2e | NAP | MlnE | / | 0.688 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.687 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.686 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.683 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.683 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.682 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.681 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.681 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.680 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.679 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.678 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.678 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.677 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.676 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.675 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.675 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.675 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.674 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.674 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.674 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.673 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.673 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.673 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.671 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.671 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.670 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.670 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 5je4 | SAH | Methyl transferase | / | 0.670 | |
| 4o29 | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.669 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.668 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.668 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.667 | |
| 4fp9 | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.667 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.666 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.666 | |
| 3v8v | SAM | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.665 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.664 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.663 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.663 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.663 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.663 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.663 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.663 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.662 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.662 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.662 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.661 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.661 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.660 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.659 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.659 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.658 | |
| 1wg8 | SAM | Ribosomal RNA small subunit methyltransferase H | / | 0.658 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.658 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.658 | |
| 3qvx | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.658 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.658 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.656 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.656 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.656 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.656 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.655 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.655 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.654 | |
| 1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.654 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.654 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.654 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.654 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.654 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.654 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.653 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.653 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.652 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.652 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.652 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.651 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.651 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.651 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.651 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.651 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.650 | |
| 1wy7 | SAH | Uncharacterized protein | / | 0.650 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 | |
| 3grv | ADN | Probable ribosomal RNA small subunit methyltransferase A | / | 0.650 |