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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3utf FDA UDP-galactopyranose mutase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3utf FDAUDP-galactopyranose mutase / 1.374
4u8p FDAUDP-galactopyranose mutase / 1.351
4u8l FDAUDP-galactopyranose mutase / 1.348
4gde FDAUDP-galactopyranose mutase / 1.347
4u8k FDAUDP-galactopyranose mutase / 1.345
3utg FDAUDP-galactopyranose mutase / 1.336
4u8n FDAUDP-galactopyranose mutase / 1.336
4wx1 FDAUDP-galactopyranose mutase / 1.329
4u8m FDAUDP-galactopyranose mutase / 1.324
4u8i FDAUDP-galactopyranose mutase / 1.316
4u8j FDAUDP-galactopyranose mutase / 1.316
3uth FDAUDP-galactopyranose mutase / 1.309
4u8o FDAUDP-galactopyranose mutase / 1.306
4dsh FDAUncharacterized protein / 1.180
3ukl FADUDP-galactopyranose mutase / 1.151
3ukf FDAUDP-galactopyranose mutase / 1.069
4dsg FADUncharacterized protein / 1.052
3ukk FADUDP-galactopyranose mutase / 0.986
3ukk FDAUDP-galactopyranose mutase / 0.976
3uka FADUDP-galactopyranose mutase / 0.919
3kve FADL-amino-acid oxidase / 0.898
5hhf FDAUDP-galactopyranose mutase / 0.891
2jb2 FADL-amino acid oxidase / 0.855
1f8s FADL-amino-acid oxidase 1.4.3.2 0.849
2iid FADL-amino-acid oxidase 1.4.3.2 0.837
3ute FADUDP-galactopyranose mutase / 0.836
2jae FADL-amino acid oxidase / 0.824
2jb1 FADL-amino acid oxidase / 0.820
2y48 FADLysine-specific histone demethylase 1A 1 0.820
3we0 FADLysine 2-monooxygenase / 0.818
1z6l FADPolyamine oxidase FMS1 / 0.813
2iw5 FADLysine-specific histone demethylase 1A 1 0.812
3int FDAUDP-galactopyranose mutase 5.4.99.9 0.804
1rsg FADPolyamine oxidase FMS1 / 0.803
2bi8 FADUDP-galactopyranose mutase 5.4.99.9 0.803
1yy5 FADPolyamine oxidase FMS1 / 0.800
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.799
4gcm FADThioredoxin reductase 1.8.1.9 0.798
2q7v FADThioredoxin reductase / 0.795
4gdc FADUDP-galactopyranose mutase / 0.794
4rsl FADFructosyl peptide oxidase / 0.794
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.793
4i58 FADCyclohexylamine Oxidase / 0.793
5l3d FADLysine-specific histone demethylase 1A 1 0.787
3cgc FADCoenzyme A disulfide reductase / 0.786
3r9u FADThioredoxin reductase / 0.781
4fwf FADLysine-specific histone demethylase 1B 1 0.781
3bi2 FADPolyamine oxidase FMS1 / 0.773
4gdd FADUDP-galactopyranose mutase / 0.773
3cn8 FADPolyamine oxidase FMS1 / 0.768
3cnd FADPolyamine oxidase FMS1 / 0.766
2xvi FADPutative flavin-containing monooxygenase / 0.765
2e1m FADL-glutamate oxidase / 0.764
4mo2 FDAUDP-galactopyranose mutase / 0.764
1jnr FADAdenylylsulfate reductase, subunit A (AprA) / 0.761
1e1m FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.760
3kyb FADUDP-galactopyranose mutase 5.4.99.9 0.760
3rha FDAPutrescine oxidase / 0.760
3cnt FADPolyamine oxidase FMS1 / 0.759
2vqb FADPutative flavin-containing monooxygenase / 0.758
2yr5 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.758
4gdp FADPolyamine oxidase FMS1 / 0.758
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.757
1e6e FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.757
2yg6 FADPutrescine oxidase / 0.757
1tdn FADL-amino-acid oxidase 1.4.3.2 0.756
5g3t FDAFlavin-dependent L-tryptophan oxidase VioA / 0.756
3hdy FADUDP-galactopyranose mutase / 0.755
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.753
3kpf FADPolyamine oxidase 1.5.3.14 0.753
4fwj FADLysine-specific histone demethylase 1B 1 0.753
4mo2 FADUDP-galactopyranose mutase / 0.753
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.752
3lov FADProtoporphyrinogen oxidase / 0.751
2b9x FADPutative aminooxidase / 0.750
3cge FADCoenzyme A disulfide reductase / 0.750
2b9w FADPutative aminooxidase / 0.749
1gte FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.748
1h7w FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.748
1reo FADL-amino-acid oxidase 1.4.3.2 0.748
2gmh FADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial 1.5.5.1 0.748
3f8d FADNADH oxidase/thioredoxin reductase / 0.748
1h83 FADPolyamine oxidase 1.5.3.14 0.747
1nhp FADNADH peroxidase 1.11.1.1 0.746
1nhr FADNADH peroxidase 1.11.1.1 0.746
1tdo FADL-amino-acid oxidase 1.4.3.2 0.744
3ict FADCoenzyme A disulfide reductase / 0.742
1nhq FADNADH peroxidase 1.11.1.1 0.741
4xbf FADLysine-specific histone demethylase 1A 1 0.741
3ab1 FADFerredoxin--NADP reductase 1.18.1.2 0.740
1f8r FADL-amino-acid oxidase 1.4.3.2 0.738
3ish FADThioredoxin reductase 1.8.1.9 0.738
2dw4 FADLysine-specific histone demethylase 1A 1 0.737
2uxx FAJLysine-specific histone demethylase 1A 1 0.737
3m12 FADMonomeric sarcosine oxidase 1.5.3.1 0.737
4d03 FADPhenylacetone monooxygenase 1.14.13.92 0.737
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.735
1tdk FADL-amino-acid oxidase 1.4.3.2 0.734
1tde FADThioredoxin reductase 1.8.1.9 0.733
2yg4 FADPutrescine oxidase / 0.733
3zdn FADMonoamine oxidase N 1.4.3.4 0.733
2vou FAD2,6-dihydroxypyridine 3-monooxygenase 1.14.13.10 0.732
3he3 FADUDP-galactopyranose mutase / 0.732
2npx FADNADH peroxidase 1.11.1.1 0.731
4ech FADPolyamine oxidase FMS1 / 0.730
2vvl FADMonoamine oxidase N 1.4.3.4 0.729
3k7t FAD6-hydroxy-L-nicotine oxidase / 0.729
2xvf FADPutative flavin-containing monooxygenase / 0.727
3cgb FADCoenzyme A disulfide reductase / 0.727
3cgd FADCoenzyme A disulfide reductase / 0.727
3m0o FADMonomeric sarcosine oxidase 1.5.3.1 0.727
4d04 FADPhenylacetone monooxygenase 1.14.13.92 0.726
4fx9 FADCoenzyme A disulfide reductase 1.8.1.14 0.726
4guu FA9Lysine-specific histone demethylase 1B 1 0.724
2yg3 FADPutrescine oxidase / 0.721
4yry FADGlutamate synthase, beta subunit / 0.720
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.719
1xpq FADPolyamine oxidase FMS1 / 0.718
4rpg FADUDP-galactopyranose mutase 5.4.99.9 0.717
1y56 FAD382aa long hypothetical sarcosine oxidase / 0.715
3mj4 FADUDP-galactopyranose mutase / 0.715
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.714
4gur FADLysine-specific histone demethylase 1B 1 0.714
3lzx FADFerredoxin--NADP reductase 2 1.18.1.2 0.713
2vq7 FADPutative flavin-containing monooxygenase / 0.712
3dk8 FADGlutathione reductase, mitochondrial 1.8.1.7 0.712
3ka7 FADPutative oxidoreductase / 0.712
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.711
2qa1 FADPgaE / 0.711
3rnm FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.711
4gus FADLysine-specific histone demethylase 1B 1 0.710
1geu FADGlutathione reductase 1.8.1.7 0.709
3gsi FADDimethylglycine oxidase 1.5.3.10 0.709
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.708
2ba9 FADPutative aminooxidase / 0.707
2yg5 FADPutrescine oxidase / 0.707
4opt FDAConserved Archaeal protein / 0.707
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.706
1v0j FADUDP-galactopyranose mutase 5.4.99.9 0.705
2gqw FADFerredoxin reductase / 0.705
2yg7 FADPutrescine oxidase / 0.705
3cty FADProbable thioredoxin reductase / 0.705
4b69 FADL-ornithine N(5)-monooxygenase / 0.705
2h94 FADLysine-specific histone demethylase 1A 1 0.704
1nhs FADNADH peroxidase 1.11.1.1 0.703
2fjb SFDAdenylylsulfate reductase, subunit A (AprA) / 0.703
3rp8 FADFAD-dependent urate hydroxylase / 0.703
2fja FADAdenylylsulfate reductase, subunit A (AprA) / 0.702
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.702
3ad9 FADSubunit beta of sarcosine oxidase / 0.702
4gut FADLysine-specific histone demethylase 1B 1 0.702
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.701
1trb FADThioredoxin reductase 1.8.1.9 0.701
2b9y FADPutative aminooxidase / 0.701
2gr0 FADFerredoxin reductase / 0.701
4h4t FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.701
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.700
1tdf FADThioredoxin reductase 1.8.1.9 0.700
1zmd FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.700
3ef6 FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.699
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.698
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.697
3pl8 FADPyranose 2-oxidase / 0.697
1gre FADGlutathione reductase, mitochondrial 1.8.1.7 0.696
1h81 FADPolyamine oxidase 1.5.3.14 0.696
2c3c FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.696
3urh FADDihydrolipoyl dehydrogenase / 0.695
5j60 FADThioredoxin reductase / 0.695
1f8w FADNADH peroxidase 1.11.1.1 0.694
2igo FADPyranose 2-oxidase / 0.694
4hsu FADLysine-specific histone demethylase 1B 1 0.694
5g3s FDAFlavin-dependent L-tryptophan oxidase VioA / 0.694
1f3p FADFerredoxin reductase / 0.692
1ger FADGlutathione reductase 1.8.1.7 0.692
1gsn FADGlutathione reductase, mitochondrial 1.8.1.7 0.692
3k4c FADPyranose 2-oxidase / 0.691
3kkj FADRenalase / 0.691
4eqx FADCoenzyme A disulfide reductase / 0.691
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.690
2eq7 FADDihydrolipoyl dehydrogenase / 0.689
4rpj FADUDP-galactopyranose mutase 5.4.99.9 0.689
3klj FADNADH-rubredoxin oxidoreductase 1.18.1.1 0.688
2yvj FADFerredoxin reductase / 0.687
1mo9 FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.686
3vqr FADPutative oxidoreductase / 0.686
4u2l SFDCholesterol oxidase 1.1.3.6 0.686
2hko FADLysine-specific histone demethylase 1A 1 0.685
4ynt FDAGlucose oxidase, putative / 0.685
1npx FADNADH peroxidase 1.11.1.1 0.684
2a87 FADThioredoxin reductase 1.8.1.9 0.684
2bi7 FADUDP-galactopyranose mutase 5.4.99.9 0.684
4k2x FADPolyketide oxygenase/hydroxylase / 0.684
1jnz FADAdenylylsulfate reductase, subunit A (AprA) / 0.683
1v59 FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.683
2ylx FADPhenylacetone monooxygenase 1.14.13.92 0.683
4bv6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.683
4h4z FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.683
2xls FADPutative flavin-containing monooxygenase / 0.682
3qj4 FADRenalase / 0.682
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.682
4mih FADPyranose 2-oxidase 1.1.3.10 0.682
2ywl FADThioredoxin reductase related protein / 0.681
4ykg FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.681
2gvc FADThiol-specific monooxygenase 1.14.13 0.680
2qae FADDihydrolipoyl dehydrogenase 1.8.1.4 0.680
4udq FAD5-(hydroxymethyl)furfural oxidase / 0.679
4z26 FADPutative GMC-type oxidoreductase R135 1 0.679
5cku FADL-ornithine N(5)-monooxygenase / 0.679
5fs7 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.679
1zx9 FADMercuric reductase 1.16.1.1 0.678
3s55 NADPutative short-chain dehydrogenase/reductase / 0.678
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.678
2yqu FADDihydrolipoyl dehydrogenase / 0.677
4h4v FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.677
4h4x FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.677
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.676
3bg7 FADPyranose 2-oxidase / 0.676
3grs FADGlutathione reductase, mitochondrial 1.8.1.7 0.676
3lsi FADPyranose 2-oxidase / 0.676
3lzw FADFerredoxin--NADP reductase 2 1.18.1.2 0.676
4h2n FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.676
4b1b FADThioredoxin reductase 1.8.1.9 0.675
5hxw FADL-amino acid deaminase / 0.675
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.674
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.674
2rab FADGlutathione amide reductase / 0.674
2xlr FADPutative flavin-containing monooxygenase / 0.674
3dk9 FADGlutathione reductase, mitochondrial 1.8.1.7 0.674
2c4c FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.673
4ntd FADThioredoxin reductase / 0.673
2xlp FADPutative flavin-containing monooxygenase / 0.672
3hdy FDAUDP-galactopyranose mutase / 0.672
3sm8 FNKFAD-dependent catabolic D-arginine dehydrogenase DauA / 0.672
1c0l FADD-amino-acid oxidase 1.4.3.3 0.671
1gv4 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.671
2du8 FADD-amino-acid oxidase 1.4.3.3 0.671
3f6s FMNFlavodoxin / 0.671
3atq FDAConserved Archaeal protein / 0.670
3lad FADDihydrolipoyl dehydrogenase / 0.670
4bjz FADProbable salicylate monooxygenase / 0.670
1c0k FADD-amino-acid oxidase 1.4.3.3 0.669
2yls FADPhenylacetone monooxygenase 1.14.13.92 0.669
4emj FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.669
1d7y FADFerredoxin reductase / 0.668
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.668
5er0 FADUncharacterized NAD(FAD)-dependent dehydrogenase / 0.668
3nix FADFlavoprotein/dehydrogenase / 0.667
4rph FADUDP-galactopyranose mutase 5.4.99.9 0.667
4udr FAD5-(hydroxymethyl)furfural oxidase / 0.667
4opc FDAConserved Archaeal protein / 0.665
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.664
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.664
4wqm FADToluene-4-monooxygenase electron transfer component 1.18.1.3 0.664
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.664
1rp0 AHZThiamine thiazole synthase, chloroplastic / 0.663
2q0k FADThioredoxin reductase 1.8.1.9 0.663
3s5w FADL-ornithine N(5)-monooxygenase / 0.663
4jq9 FADDihydrolipoyl dehydrogenase / 0.663
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.662
2r9z FADGlutathione amide reductase / 0.662
4o5u FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.662
4wct FADFructosyl amine:oxygen oxidoreductase / 0.662
5a8a FMNRiboflavin biosynthesis protein RibF 2.7.1.26 0.662
3dgz FADThioredoxin reductase 2, mitochondrial 1.8.1.9 0.661
3m13 FADMonomeric sarcosine oxidase 1.5.3.1 0.661
4rhe FMNFlavin prenyltransferase UbiX / 0.661
4z24 FADPutative GMC-type oxidoreductase R135 1 0.661
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.660
2v5u FMNFlavodoxin / 0.660
3ada NADSubunit alpha of sarocosine oxidase / 0.660
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.660
4ocg FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.660
1feb FADTrypanothione reductase 1.8.1.12 0.659
1lvl FADDihydrolipoyl dehydrogenase 1.8.1.4 0.659
1qo8 FADFumarate reductase flavoprotein subunit / 0.659
4h4r FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.659
1ebd FADDihydrolipoyl dehydrogenase 1.8.1.4 0.658
4ykf FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.658
1dnc FADGlutathione reductase, mitochondrial 1.8.1.7 0.657
2z6c FMNPhototropin-1 2.7.11.1 0.657
3f8p NADNADH oxidase/thioredoxin reductase / 0.657
3up4 FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.657
1ng4 FADGlycine oxidase 1.4.3.19 0.656
2o06 MTASpermidine synthase 2.5.1.16 0.656
3axb FADPutative oxidoreductase / 0.656
4mok FADPyranose 2-oxidase / 0.656
4uir FADOleate hydratase 4.2.1.53 0.656
1bwc FADGlutathione reductase, mitochondrial 1.8.1.7 0.655
2fjd SFDAdenylylsulfate reductase, subunit A (AprA) / 0.655
3dgh FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.655
3uoy FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.655
4nev FADTrypanothione reductase / 0.655
4u2t FADCholesterol oxidase 1.1.3.6 0.655
1lpf FADDihydrolipoyl dehydrogenase 1.8.1.4 0.654
4h4w FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.654
1cbo FADCholesterol oxidase 1.1.3.6 0.653
1get FADGlutathione reductase 1.8.1.7 0.653
2ign FADPyranose 2-oxidase / 0.653
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.653
5buk FADFADH2-dependent halogenase / 0.653
3fbs FADOxidoreductase / 0.652
3k30 ADPHistamine dehydrogenase / 0.652
3lsm SFDPyranose 2-oxidase / 0.652
5dbj FADFADH2-dependent halogenase PltA / 0.652
1ges FADGlutathione reductase 1.8.1.7 0.651
1h2h NADL-aspartate dehydrogenase 1.4.1.21 0.651
1npt NADGlyceraldehyde-3-phosphate dehydrogenase / 0.651
2tpr FADTrypanothione reductase 1.8.1.12 0.651
3atr FDAConserved Archaeal protein / 0.651
3dme FADPutative conserved exported protein / 0.651
3fpz AHZThiamine thiazole synthase / 0.651
3qfa FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.651
4nte FADDepH / 0.651
3wv8 ATPHmd co-occurring protein HcgE / 0.650
4j31 FADKynurenine 3-monooxygenase / 0.650