sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2wsb | NAD | Galactitol dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2wsb | NAD | Galactitol dehydrogenase | / | 1.253 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 1.056 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.982 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.978 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.977 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.964 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.960 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.944 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.939 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.938 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.922 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.911 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.910 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.905 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.904 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.899 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.899 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.895 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.895 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.889 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.889 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.889 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.886 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.886 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.882 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.880 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.878 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.872 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.868 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.865 | |
| 4qec | NAP | ElxO | / | 0.864 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.859 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.858 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.855 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.854 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.851 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.851 | |
| 4kwh | NAP | Reductase homolog | / | 0.851 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.850 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.848 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.845 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.844 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.843 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.841 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.840 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.840 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.840 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.840 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.840 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.839 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.837 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.833 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.831 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.831 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.830 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.829 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.826 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.825 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.824 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.823 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.823 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.821 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.818 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.818 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.817 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.817 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.817 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.816 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.812 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.811 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.811 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.811 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.810 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.809 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.809 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.809 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.809 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.808 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.808 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.807 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.807 | |
| 4hxy | NDP | Plm1 | / | 0.807 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.805 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.799 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.799 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.798 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.797 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.797 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.795 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.794 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.794 | |
| 4qed | NAP | ElxO | / | 0.794 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.793 | |
| 3uce | NDP | Dehydrogenase | / | 0.790 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.789 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.786 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.786 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.786 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.784 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.783 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.783 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.781 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.781 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.780 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.780 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.780 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.779 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.779 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.779 | |
| 1iy8 | NAD | Levodione reductase | / | 0.778 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.778 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.777 | |
| 3mje | NDP | AmphB | / | 0.777 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.775 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.775 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.774 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.774 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.773 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.771 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.768 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.768 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.768 | |
| 4u7w | NDP | MxaA | / | 0.768 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.766 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.766 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.765 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.764 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.764 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.763 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.763 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.762 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.762 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.761 | |
| 5d2e | NAP | MlnE | / | 0.761 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.760 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.759 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.759 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.758 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.755 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.754 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.751 | |
| 1sny | NAP | LD36273p | / | 0.751 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.751 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.750 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.746 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.745 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.745 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.744 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.744 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.740 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.737 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.735 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.735 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.734 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.734 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.731 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.731 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.730 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.729 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.729 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.729 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.728 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.725 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.724 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.723 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.723 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.723 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.722 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.721 | |
| 3sju | NDP | Keto reductase | / | 0.719 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.717 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.717 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.716 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.715 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.714 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.713 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.712 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.711 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.710 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.710 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.710 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.709 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.709 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.708 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.708 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.708 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.708 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.706 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.705 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.705 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.704 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.703 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.703 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.702 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.701 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.701 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.700 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.699 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.699 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.699 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.698 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.698 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.697 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.697 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.697 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.695 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.694 | |
| 3oa2 | NAD | UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase | / | 0.694 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.694 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.694 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.694 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.692 | |
| 2ixb | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.692 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.691 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.689 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.688 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.688 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 3adp | NAI | Lambda-crystallin | 1.1.1.45 | 0.688 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.688 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.686 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.686 | |
| 3abi | NAD | Uncharacterized protein | / | 0.686 | |
| 4fp9 | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.686 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.685 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.685 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.683 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.682 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.682 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.682 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.682 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.681 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.681 | |
| 1x7d | NAD | Putative ornithine cyclodeaminase | / | 0.681 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.681 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.681 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.681 | |
| 1u7h | NAD | Putative ornithine cyclodeaminase | / | 0.680 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.679 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.679 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.679 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.678 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.675 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.675 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.675 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.675 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.675 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.673 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.672 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.672 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.672 | |
| 2fze | APR | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.671 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.669 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.669 | |
| 2hms | NAI | Ktr system potassium uptake protein A | / | 0.669 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.668 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.668 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.668 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.667 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.667 | |
| 1sc6 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.667 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.667 | |
| 4clo | NAP | Pteridine reductase | / | 0.667 | |
| 4kvz | SAH | PtnL protein | / | 0.667 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.666 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.666 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.666 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.666 | |
| 3q87 | SAM | N6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY) | / | 0.666 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.666 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.666 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.665 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.665 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.665 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.664 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.663 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.663 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.661 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.661 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.661 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.661 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.660 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.660 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.660 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.658 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.658 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.658 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.658 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.657 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.657 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.657 | |
| 3u81 | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.656 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.655 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.655 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.654 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.654 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.653 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.653 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.653 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.652 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.652 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.651 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.651 | |
| 3m2t | NAD | Probable dehydrogenase | / | 0.650 | |
| 4pyn | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.650 |