sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3jwm | 5WB | Dihydrofolate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3jwm | 5WB | Dihydrofolate reductase | / | 1.000 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.600 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.594 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.592 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.589 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.588 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.588 | |
| 3cse | N22 | Uncharacterized protein | / | 0.586 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.568 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.562 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.559 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
| 3eek | 53S | Uncharacterized protein | / | 0.552 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.549 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.546 | |
| 3eel | 53T | Uncharacterized protein | / | 0.543 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.543 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.543 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.541 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.541 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.535 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.533 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.531 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.531 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.530 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.526 | |
| 3eej | 53R | Uncharacterized protein | / | 0.526 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.521 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.520 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.520 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.520 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.519 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.518 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.518 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.516 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3qly | 55V | Uncharacterized protein | / | 0.512 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.511 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.510 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.509 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.507 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.505 | |
| 3eem | 53V | Uncharacterized protein | / | 0.504 | |
| 4l9q | 9TP | Serum albumin | / | 0.504 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.503 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.502 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.499 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.499 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.498 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.496 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.493 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.488 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.487 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.487 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.487 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.487 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.486 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.485 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.485 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.484 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.484 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.481 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.481 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.480 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.479 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.478 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.477 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.477 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.476 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.476 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.476 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.476 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.475 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.475 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.475 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.474 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.473 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.472 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.472 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.471 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.471 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.471 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.469 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.469 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.468 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.468 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.468 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.468 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.467 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.467 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.466 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.466 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.465 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4egn | TWO | Cytochrome P450 | / | 0.465 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.464 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.464 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.464 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.464 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.463 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.463 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.463 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1ysx | 4EB | Serum albumin | / | 0.462 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.462 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.462 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.462 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.462 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.461 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.461 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.461 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.460 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.459 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.459 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.459 | |
| 3zuy | TCH | Transporter | / | 0.459 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.459 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.458 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.458 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.458 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.458 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.458 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.458 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.457 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.457 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.457 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.457 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.456 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.456 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.456 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.456 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.456 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.456 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.456 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.455 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.455 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.454 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.453 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.453 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1pp9 | SMA | Cytochrome b | / | 0.453 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.453 | |
| 2jfa | RAL | Estrogen receptor | / | 0.453 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.453 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.453 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.452 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.452 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.451 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.451 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.451 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.451 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2uzh | IPE | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.451 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.451 | |
| 3tdl | 11D | Serum albumin | / | 0.451 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.451 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.450 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.450 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3q30 | D61 | Squalene synthase | 2.5.1.21 | 0.450 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.450 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.450 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.450 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.450 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.449 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.449 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.449 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.449 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.449 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.449 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.449 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.449 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.448 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.448 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.448 | |
| 2acw | UPG | Glycosyltransferase | / | 0.448 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.448 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.448 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.448 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.448 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.447 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.447 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.447 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.447 | |
| 4f9w | LM4 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.447 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.447 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.446 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1p7t | ACO | Malate synthase G | / | 0.446 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.446 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.446 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.446 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3h18 | PMS | Esterase/lipase | / | 0.446 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4l8u | 9AZ | Serum albumin | / | 0.446 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.446 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.445 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.445 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.445 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.445 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.445 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.445 | |
| 3jt8 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.445 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.445 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.444 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.444 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.444 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.444 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.444 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4k9v | 6AW | Cytochrome P450 3A4 | / | 0.444 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.444 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.444 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.443 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.443 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.443 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.443 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3uow | XMP | GMP synthase [glutamine-hydrolyzing] | / | 0.443 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.443 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.443 | |
| 4v12 | POG | MaoC like domain protein | / | 0.443 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.442 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.442 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3dol | GWI | Pol protein | / | 0.442 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.442 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.442 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.441 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.441 | |
| 1t1s | CBQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.441 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3p9t | TCL | Repressor | / | 0.441 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.441 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.441 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.441 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.440 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.440 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.440 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3ele | PLP | Aminotransferase | / | 0.440 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.440 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.440 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.440 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.440 |