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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q7gCCLPyrrolysine--tRNA ligase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2q7gCCLPyrrolysine--tRNA ligase/1.000
2zioAYBPyrrolysine--tRNA ligase/0.599
2zcePYLPyrrolysine--tRNA ligase/0.581
3vqxBLKPyrrolysine--tRNA ligase/0.544
3vqvANPPyrrolysine--tRNA ligase/0.530
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.510
1og5SWFCytochrome P450 2C9/0.507
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.505
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.501
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.500
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.498
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.498
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.496
1vzaUMPThymidylate synthase/0.494
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.494
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.493
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.493
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.491
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.491
4dscA8SAbscisic acid receptor PYL3/0.491
3r6pA8SAbscisic acid receptor PYL10/0.490
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.489
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.488
3sai9DRDihydrofolate reductase/0.488
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.488
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.486
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
1o76CAMCamphor 5-monooxygenase1.14.15.10.484
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.483
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.483
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.481
1pdhFASp-hydroxybenzoate hydroxylase/0.480
1uy7PU4Heat shock protein HSP 90-alpha/0.480
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.480
3tk3CPZCytochrome P450 2B41.14.14.10.478
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.477
1bozPRDDihydrofolate reductase1.5.1.30.476
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.476
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
4pkl1GHUncharacterized protein/0.476
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.475
1rx7FOLDihydrofolate reductase1.5.1.30.475
3njoP2MAbscisic acid receptor PYR1/0.475
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
5cccDDFDihydrofolate reductase1.5.1.30.475
1ia3TQ5Dihydrofolate reductase1.5.1.30.474
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.474
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
3h3t16HCollagen type IV alpha-3-binding protein/0.474
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
3nj0PYVAbscisic acid receptor PYL2/0.473
3njoPYVAbscisic acid receptor PYR1/0.473
3nmpPYVAbscisic acid receptor PYL2/0.472
1njaDCMThymidylate synthase/0.471
2vcmM11Isopenicillin N synthase1.21.3.10.471
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
1jtqLY3Thymidylate synthase/0.470
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.470
2pulACPMethylthioribose kinase2.7.1.1000.470
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
4m2xTMQDihydrofolate reductase1.5.1.30.470
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.470
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.469
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.468
1ia1TQ3Dihydrofolate reductase1.5.1.30.468
1jutLYDThymidylate synthase/0.468
3hub469Mitogen-activated protein kinase 14/0.468
4ap1NAPSteroid monooxygenase/0.468
1xddAAYIntegrin alpha-L/0.467
2pmnK51Protein kinase 7/0.467
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.466
4cdmFO1Deoxyribodipyrimidine photolyase/0.466
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
5d7pAR6NAD-dependent protein deacetylase sirtuin-23.5.10.466
2zbaZBATrichothecene 3-O-acetyltransferase/0.465
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3sa27DRDihydrofolate reductase/0.465
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.465
4kfj1R0Dihydrofolate reductase1.5.1.30.465
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
4ele31IDihydrofolate reductase/0.464
4h9614QDihydrofolate reductase1.5.1.30.464
4h9753SDihydrofolate reductase1.5.1.30.464
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.464
2hb8MVDVitamin D3 receptor/0.463
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2ykbYKBHeat shock protein HSP 90-alpha/0.463
2zzaFOLDihydrofolate reductase/0.463
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3negPYVAbscisic acid receptor PYL1/0.463
3oafOAGDihydrofolate reductase1.5.1.30.463
1aoeGW3Dihydrofolate reductase1.5.1.30.462
1klkPMDDihydrofolate reductase1.5.1.30.462
1ove358Mitogen-activated protein kinase 14/0.462
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.462
3vt9YI4Vitamin D3 receptor/0.462
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
1ie9VDXVitamin D3 receptor/0.461
1m78CLZDihydrofolate reductase1.5.1.30.461
3nglNAPBifunctional protein FolD/0.461
3nr4PYVAbscisic acid receptor PYL2/0.461
3qlrQLRDihydrofolate reductase1.5.1.30.461
3qly55VUncharacterized protein/0.461
3srsM23Dihydrofolate reductase1.5.1.30.461
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.461
1s3yTQTDihydrofolate reductase1.5.1.30.460
3adaNADSubunit alpha of sarocosine oxidase/0.460
3qlrNDPDihydrofolate reductase1.5.1.30.460
3sh25DRDihydrofolate reductase1.5.1.30.460
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.459
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3jwcEKBDihydrofolate reductase/0.459
3ql3FOLDihydrofolate reductase1.5.1.30.459
3qlzQLZUncharacterized protein/0.459
3qm4PN0Cytochrome P450 2D6/0.459
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.459
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4iui1GQEstrogen receptor/0.459
4jlm1NNDeoxycytidine kinase2.7.1.740.459
1db1VDXVitamin D3 receptor/0.458
1fmjRTLRetinol dehydratase/0.458
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.458
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1vj3TABDihydrofolate reductase1.5.1.30.458
1vzbUMPThymidylate synthase/0.458
2yjxYJXHeat shock protein HSP 90-alpha/0.458
3eigMTXDihydrofolate reductase1.5.1.30.458
3p3zP3ZPutative cytochrome P450/0.458
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
4lsjLSJGlucocorticoid receptor/0.458
1dz4CAMCamphor 5-monooxygenase1.14.15.10.457
1gwrESTEstrogen receptor/0.457
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
1m7aMQUDihydrofolate reductase1.5.1.30.457
1m8h6NINitric oxide synthase, inducible1.14.13.390.457
1phhFADp-hydroxybenzoate hydroxylase/0.457
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.457
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2ouzC3DEstrogen receptor/0.457
3ns2PYVAbscisic acid receptor PYL2/0.457
3nxvD2FDihydrofolate reductase1.5.1.30.457
4alhA9PBromodomain-containing protein 2/0.457
4bwaN0BPyrrolysine--tRNA ligase/0.457
4i8vBHFCytochrome P450 1A11.14.14.10.457
2ovmAS0Progesterone receptor/0.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
3vtcTK3Vitamin D3 receptor/0.456
3zvuA8SAbscisic acid receptor PYR1/0.456
4c3yANB3-ketosteroid dehydrogenase/0.456
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.456
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4ixeIXEDihydrofolate reductase1.5.1.30.456
4uyf73BBromodomain-containing protein 2/0.456
1dajMOTDihydrofolate reductase1.5.1.30.455
1njcDCMThymidylate synthase/0.455
2fai459Estrogen receptor/0.455
2hcdBIVVitamin D3 receptor A/0.455
3otwCOAPhosphopantetheine adenylyltransferase/0.455
1m79MQ1Dihydrofolate reductase1.5.1.30.454
1m9k7NINitric oxide synthase, endothelial1.14.13.390.454
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
3zsh469Mitogen-activated protein kinase 14/0.454
4g1z0VPVitamin D3 receptor A/0.454
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.454
1uy9PU6Heat shock protein HSP 90-alpha/0.453
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.453
2hasC3OVitamin D3 receptor/0.453
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.453
1nq7ARLNuclear receptor ROR-beta/0.452
1x8lOXRRetinol dehydratase/0.452
2jn3JN3Fatty acid-binding protein, liver/0.452
2tscCB3Thymidylate synthase/0.452
3gc9B45Mitogen-activated protein kinase 112.7.11.240.452
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.452
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4jdaA9SAbscisic acid receptor PYL3/0.452
1e26GPBDihydrofolate reductase1.5.1.30.451
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.451
2g86UMPThymidylate synthase/0.451
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.451
3egvSAHRibosomal protein L11 methyltransferase2.1.10.451
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3pm0BHFCytochrome P450 1B1/0.451
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1hfqMOTDihydrofolate reductase1.5.1.30.450
1q5dEPBEpothilone C/D epoxidase1.140.450
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2hamC33Vitamin D3 receptor/0.450
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.450
3dr1C5DVitamin D3 receptor A/0.450
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3inxJZCHeat shock protein HSP 90-alpha/0.450
3w5q3KLVitamin D3 receptor/0.450
3w5rLOAVitamin D3 receptor/0.450
4g3rCAMCamphor 5-monooxygenase1.14.15.10.450
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.450
4nh82LCHeat shock protein HSP 90-alpha/0.450
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.450
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2a1nCAMCamphor 5-monooxygenase1.14.15.10.449
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2z97CAMCamphor 5-monooxygenase1.14.15.10.449
2zevB71Geranylgeranyl pyrophosphate synthase/0.449
3cseN22Uncharacterized protein/0.449
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.449
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
4g1d0VKVitamin D3 receptor A/0.449
4wa9AXITyrosine-protein kinase ABL12.7.10.20.449
1dgfNDPCatalase1.11.1.60.448
1kt3RTLRetinol-binding protein 4/0.448
1m13HYFNuclear receptor subfamily 1 group I member 2/0.448
1ndeMONEstrogen receptor beta/0.448
1nhz486Glucocorticoid receptor/0.448
1pydTDPPyruvate decarboxylase isozyme 1/0.448
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
2uxoTACHTH-type transcriptional regulator TtgR/0.448
2ykeYKEHeat shock protein HSP 90-alpha/0.448
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.448
3v94WYQPhosphodiesterase/0.448
3vruYS3Vitamin D3 receptor/0.448
3vtdTKDVitamin D3 receptor/0.448
3w0hW12Vitamin D3 receptor/0.448
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.448
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4h9814QUncharacterized protein/0.448
4ixfIXFDihydrofolate reductase1.5.1.30.448
4lg5A1OAbscisic acid receptor PYL2/0.448
1synF89Thymidylate synthase/0.447
2gr1FADFerredoxin reductase/0.447
2oaxSNLMineralocorticoid receptor/0.447
2vbpVB1Isopenicillin N synthase1.21.3.10.447
2w3aTOPDihydrofolate reductase1.5.1.30.447
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.447
3d0bSNXHeat shock protein HSP 90-alpha/0.447
3itzP66Mitogen-activated protein kinase 14/0.447
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
1rk3VDXVitamin D3 receptor/0.446
1uyiPUZHeat shock protein HSP 90-alpha/0.446
1uykPUXHeat shock protein HSP 90-alpha/0.446
2h55DZ8Heat shock protein HSP 90-alpha/0.446
2qblCAMCamphor 5-monooxygenase1.14.15.10.446
3koo24DBifunctional epoxide hydrolase 23.3.2.100.446
3ua506XCytochrome P450 2B61.14.130.446
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.446
4mv8ACPBiotin carboxylase6.3.4.140.446
4nc3ERM5-hydroxytryptamine receptor 2B/0.446
1ie8KH1Vitamin D3 receptor/0.445
2cd2FOLDihydrofolate reductase1.5.1.30.445
2fznFADBifunctional protein PutA1.5.5.20.445
2od7A1RNAD-dependent protein deacetylase HST23.5.10.445
2wo7ASVIsopenicillin N synthase1.21.3.10.445
2y60M8FIsopenicillin N synthase1.21.3.10.445
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.445
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3l6jZ90Alr2278 protein/0.445
3vt5YI2Vitamin D3 receptor/0.445
3w5p4OAVitamin D3 receptor/0.445
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.445
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.445
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4nb6444Nuclear receptor ROR-gamma/0.445
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.445
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.444
1k6cMK1Gag-Pol polyprotein3.4.23.160.444
1lhvNOGSex hormone-binding globulin/0.444
1nceCB3Thymidylate synthase/0.444
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1x7gNAPPutative ketoacyl reductase1.3.10.444
1zzlTZYMitogen-activated protein kinase 14/0.444
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2fziDH3Dihydrofolate reductase1.5.1.30.444
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
2he5NDPAldo-keto reductase family 1 member C211.1.10.444
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2w71L23Biotin carboxylase6.3.4.140.444
2wi4ZZ4Heat shock protein HSP 90-alpha/0.444
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3w5tLHPVitamin D3 receptor/0.444
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4la7A1OAbscisic acid receptor PYL2/0.444
4p66MTXDihydrofolate reductase/0.444
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.444
4xe606UDihydrofolate reductase1.5.1.30.444
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.443
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.443
1rf7DHFDihydrofolate reductase1.5.1.30.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2gjnFMNNitronate monooxygenase1.13.12.160.443
2wleCOAPolysialic acid O-acetyltransferase/0.443
2ykcYKCHeat shock protein HSP 90-alpha/0.443
3bqdDAYGlucocorticoid receptor/0.443
3dejRXCCaspase-33.4.22.560.443
3lxiCAMCytochrome P450/0.443
3s3vTOPDihydrofolate reductase1.5.1.30.443
3zkuHCVIsopenicillin N synthase1.21.3.10.443
4bhw01KHistone acetyltransferase p300/0.443
4egnTWOCytochrome P450/0.443
4ixgIXGDihydrofolate reductase1.5.1.30.443
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1rx8FOLDihydrofolate reductase1.5.1.30.442
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.442
1txiTX5Vitamin D3 receptor/0.442
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2ea1GPGRibonuclease I3.1.27.60.442
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.442
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2x1zPIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.442
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3kpzZNEVitamin D3 receptor/0.442
3l8sBFFMitogen-activated protein kinase 14/0.442
3lfcZ86Mitogen-activated protein kinase 14/0.442
3nefPYVAbscisic acid receptor PYL1/0.442
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4a83DXCMajor pollen allergen Bet v 1-A/0.442
4a862ANMajor pollen allergen Bet v 1-A/0.442
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.442
4h9506UDihydrofolate reductase1.5.1.30.442
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4j4vSVRNucleocapsid protein/0.442
1jmgUMPThymidylate synthase/0.441
1m78NDPDihydrofolate reductase1.5.1.30.441
2a1mCAMCamphor 5-monooxygenase1.14.15.10.441
2bbqPFGThymidylate synthase/0.441
2feuCAMCamphor 5-monooxygenase1.14.15.10.441
3br3ETHTH-type transcriptional regulator QacR/0.441
3da24MDCarbonic anhydrase 134.2.1.10.441
3dhoB2MStreptogramin A acetyltransferase2.3.10.441
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3vhmNPKAvidin/0.441
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4i13FOLDihydrofolate reductase1.5.1.30.441
4lt63ATPoly(A) polymerase gamma2.7.7.190.441
4mv1ADPBiotin carboxylase6.3.4.140.441
4pnmNU1Tankyrase-22.4.2.300.441
4r20AERCytochrome P450 family 17 polypeptide 2/0.441
1hb3SCVIsopenicillin N synthase1.21.3.10.440
1hfpMOTDihydrofolate reductase1.5.1.30.440
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1t87CAMCamphor 5-monooxygenase1.14.15.10.440
1uyePU9Heat shock protein HSP 90-alpha/0.440
1xg5NAPDehydrogenase/reductase SDR family member 11/0.440
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.440
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
2aclREARetinoic acid receptor RXR-alpha/0.440
2izrBRKCasein kinase I isoform gamma-32.7.11.10.440
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.440
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.440
2zlaVDBVitamin D3 receptor/0.440
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.440
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.440
3cv9VDXVitamin D3 dihydroxylase/0.440
3ebf332Nitric oxide synthase, inducible1.14.13.390.440
3g70A5TRenin3.4.23.150.440
3oquA8SAbscisic acid receptor PYL9/0.440
3p2oNADBifunctional protein FolD/0.440
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
3ujlA8SAbscisic acid receptor PYL2/0.440
3vrwYS5Vitamin D3 receptor/0.440
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.440
4a9iP9IBromodomain-containing protein 2/0.440
4g1y0VOVitamin D3 receptor A/0.440
4ia3BIVVitamin D3 receptor A/0.440
4ifvT27Gag-Pol polyprotein2.7.7.490.440
4kak06UDihydrofolate reductase1.5.1.30.440
4lgaA2OAbscisic acid receptor PYL2/0.440
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.440