sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dux | ZST | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.806 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.768 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.747 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.747 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.734 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.719 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.716 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.707 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.700 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.700 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.699 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.699 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.698 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.695 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.685 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.685 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.677 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.671 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.671 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.669 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.657 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.651 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.649 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.648 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.642 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.641 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.625 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.624 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.621 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.620 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.619 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.618 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.608 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.606 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.603 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.600 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.596 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.595 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.593 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.591 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.589 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.583 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.581 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.570 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.569 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.565 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.561 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.554 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.538 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.510 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.509 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.491 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.491 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.490 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.489 | |
| 4kmz | FOL | Folate receptor beta | / | 0.488 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.481 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.480 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.477 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.477 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.476 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.474 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.474 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.473 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.472 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 4phl | PIL | Phosphodiesterase | / | 0.469 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.468 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.468 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.466 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.466 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.466 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.465 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.464 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.464 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3keg | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.464 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.463 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.463 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.463 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.462 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.462 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.462 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.461 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.461 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.461 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.459 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.458 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.458 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.457 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.457 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.455 | |
| 1qv0 | CZH | Obelin | / | 0.455 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.455 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.455 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.455 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.454 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.454 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.454 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.454 | |
| 4x3u | SVR | Chromobox protein homolog 7 | / | 0.454 | |
| 1s36 | CEI | Obelin | / | 0.453 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.453 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.452 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.452 | |
| 4mrx | CZH | Obelin | / | 0.452 | |
| 1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.451 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.451 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 1uhj | CZB | Aequorin-2 | / | 0.450 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.449 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.449 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.449 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.449 | |
| 1ah4 | NAP | Aldose reductase | 1.1.1.21 | 0.448 | |
| 1hqt | NAP | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.448 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.448 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.448 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.448 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2qry | TPS | Thiamine-binding periplasmic protein | / | 0.448 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.448 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.448 | |
| 3hgg | CHD | CmeR | / | 0.448 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.447 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.447 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.447 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.447 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.447 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.447 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.446 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.446 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.446 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.446 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.446 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.446 | |
| 4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.446 | |
| 4kxj | P34 | Nucleoprotein | / | 0.446 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.446 | |
| 1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.445 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2qjp | ANJ | Cytochrome b | / | 0.445 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.445 | |
| 4q7f | 3D1 | Uncharacterized protein | / | 0.445 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.445 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.444 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.444 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.443 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.443 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 2gms | P0P | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.442 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.442 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3v36 | NAP | Aldose reductase | 1.1.1.21 | 0.442 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 1dtp | APU | Diphtheria toxin | / | 0.441 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.441 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.441 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3ocw | 3AM | Lipoprotein E | / | 0.441 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3wd2 | A1L | Chitinase B | 3.2.1.14 | 0.441 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.441 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2hzq | STR | Apolipoprotein D | / | 0.440 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.440 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.440 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4n65 | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.440 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 |