sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5k0t | 415 | Methionine--tRNA ligase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5k0t | 415 | Methionine--tRNA ligase | / | 1.000 | |
| 5k0s | 0OU | Methionine--tRNA ligase | / | 0.744 | |
| 4py2 | 43E | Methionine--tRNA ligase | / | 0.601 | |
| 3arv | SAU | Chitinase A | / | 0.491 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.483 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.480 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.479 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.475 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.475 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.472 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.472 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.471 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.471 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 1ke5 | LS1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.469 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.469 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.469 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.468 | |
| 3rpy | 27Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.468 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.467 | |
| 1r2j | FAD | FkbI | / | 0.466 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.466 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.466 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.466 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.466 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.465 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.464 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.464 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.464 | |
| 1lcb | DHF | Thymidylate synthase | / | 0.463 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.462 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.462 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.462 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.462 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2c4i | BTN | Avidin | / | 0.461 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2izl | IMI | Streptavidin | / | 0.461 | |
| 2rtd | BTN | Streptavidin | / | 0.461 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.461 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4bmo | FMN | Protein NrdI | / | 0.460 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.460 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2bxm | IMN | Serum albumin | / | 0.459 | |
| 3g5k | BB2 | Peptide deformylase, mitochondrial | 3.5.1.88 | 0.459 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.459 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.459 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.458 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.458 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.458 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.458 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.458 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.457 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.457 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.457 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.456 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.456 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.455 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3up0 | D7S | aceDAF-12 | / | 0.455 | |
| 4bmp | FMN | Protein NrdI | / | 0.455 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.454 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3qzg | X67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.454 | |
| 4okt | 198 | Androgen receptor | / | 0.454 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.454 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.453 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.453 | |
| 2uz2 | BTN | Avd protein | / | 0.453 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.453 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.452 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.452 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.451 | |
| 1nja | DCM | Thymidylate synthase | / | 0.451 | |
| 1swt | BTN | Streptavidin | / | 0.451 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.451 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 3akk | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.451 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.451 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.450 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 2izf | BTN | Streptavidin | / | 0.450 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.450 | |
| 4okb | 198 | Androgen receptor | / | 0.450 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.450 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.449 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.449 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.449 | |
| 3ezv | EZV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.449 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.449 | |
| 3rdq | DTB | Streptavidin | / | 0.449 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.449 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.449 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.448 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.448 | |
| 4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.448 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.448 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.447 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.447 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.447 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.447 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 4hxn | 1A7 | Bromodomain-containing protein 4 | / | 0.447 | |
| 4lr6 | 1XA | Bromodomain-containing protein 4 | / | 0.447 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.447 | |
| 1jmg | UMP | Thymidylate synthase | / | 0.446 | |
| 1pxp | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 2acw | UPG | Glycosyltransferase | / | 0.446 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.446 | |
| 2rte | BTN | Streptavidin | / | 0.446 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1i9h | BNI | Streptavidin | / | 0.445 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.445 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3rm8 | RM8 | Acidic mammalian chitinase | 3.2.1.14 | 0.445 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.445 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.445 | |
| 1coy | AND | Cholesterol oxidase | 1.1.3.6 | 0.444 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.444 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.444 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 2xvv | 9DN | Serum albumin | / | 0.444 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.444 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.444 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.444 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.444 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.444 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.444 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.444 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 1vza | UMP | Thymidylate synthase | / | 0.443 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3c3a | ADP | Phosphoglycerate kinase 1 | 2.7.2.3 | 0.443 | |
| 3ry2 | BTN | Streptavidin | / | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 3zra | ORB | Progesterone receptor | / | 0.443 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.443 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.443 | |
| 4oea | DHT | Androgen receptor | / | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.442 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.442 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.442 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2xw1 | 9NV | Serum albumin | / | 0.442 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.442 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3qar | QAR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.442 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4edy | 9PQ | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.442 | |
| 4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.442 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4l64 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.442 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.441 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1sri | DMB | Streptavidin | / | 0.441 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1zdw | FLV | Prenyltransferase | / | 0.441 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.441 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 2j62 | GSZ | O-GlcNAcase NagJ | / | 0.441 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.441 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3mno | DEX | Glucocorticoid receptor | / | 0.441 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.441 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.441 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 1bc5 | SAH | Chemotaxis protein methyltransferase | 2.1.1.80 | 0.440 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1osv | CHC | Bile acid receptor | / | 0.440 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.440 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.440 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3oog | YTP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3t7q | RB4 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.440 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.440 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.440 |