sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nu6 | NAD | Phosphonate dehydrogenase | 1.20.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4nu6 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 1.000 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.613 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.562 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.557 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.537 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.521 | |
| 4e5m | NAP | Phosphonate dehydrogenase | 1.20.1.1 | 0.515 | |
| 1sn5 | T3 | Transthyretin | / | 0.493 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.491 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.490 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.489 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.479 | |
| 2xvu | 9DN | Serum albumin | / | 0.478 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.475 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.475 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.474 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.473 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.473 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.473 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.472 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.470 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.470 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.470 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.470 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.469 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.469 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.469 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.469 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.468 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.468 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.467 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.467 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.466 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.465 | |
| 1qvn | FRI | Interleukin-2 | / | 0.465 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.465 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.465 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.465 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.465 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.465 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.465 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.465 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.464 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.463 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.463 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.462 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.462 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.462 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.462 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.462 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.462 | |
| 1gqt | ACP | Ribokinase | / | 0.461 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.461 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.461 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.460 | |
| 2dbq | NAP | Glyoxylate reductase | 1.1.1.26 | 0.460 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.460 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.459 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.458 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.457 | |
| 1ppj | ANY | Cytochrome b | / | 0.457 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.457 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.457 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.457 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.457 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.457 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.456 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.456 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.456 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.456 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.456 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.456 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.455 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.455 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.455 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.455 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.454 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.454 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.454 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.454 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.454 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.454 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1qp8 | NDP | 2-hydroxyacid dehydrogenase | / | 0.453 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.453 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.453 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.453 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.452 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.452 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.452 | |
| 1ict | T44 | Transthyretin | / | 0.451 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.451 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2bx8 | AZQ | Serum albumin | / | 0.451 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.451 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.451 | |
| 2zaf | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.451 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.451 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.451 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 5eox | ADP | Type 4 fimbrial biogenesis protein PilM | / | 0.451 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.450 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.450 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.450 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.450 | |
| 2ydf | IO3 | Serum albumin | / | 0.450 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.450 | |
| 3lu8 | IQX | Serum albumin | / | 0.450 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.450 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.449 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 2bun | FAD | AppA protein | / | 0.449 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.449 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.449 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.449 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.449 | |
| 4hxy | NDP | Plm1 | / | 0.449 | |
| 4l8u | 9AZ | Serum albumin | / | 0.449 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.448 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.448 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.448 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.448 | |
| 3vth | APC | Carbamoyltransferase | / | 0.448 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.448 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.448 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.448 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.447 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.447 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.447 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.447 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.447 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.447 | |
| 4dja | FAD | (6-4) photolyase | / | 0.447 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.447 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.447 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.447 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.447 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.446 | |
| 1ie4 | T44 | Transthyretin | / | 0.446 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.446 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.446 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.446 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.446 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.446 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.446 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.446 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.445 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.445 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.445 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.445 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.444 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.444 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.444 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.444 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.444 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.444 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.444 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4l9k | EHF | Serum albumin | / | 0.444 | |
| 5a3c | NAD | SIR2 family protein | / | 0.444 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.444 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.443 | |
| 3tdl | 11D | Serum albumin | / | 0.443 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.443 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.443 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.443 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.442 | |
| 1g6c | TZP | Thiamine-phosphate synthase | / | 0.442 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.442 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.442 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.442 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.442 | |
| 2j8z | NAP | Quinone oxidoreductase PIG3 | 1 | 0.442 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.442 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.442 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.442 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4hjf | C2E | GGDEF family protein | / | 0.442 | |
| 4l9q | 9TP | Serum albumin | / | 0.442 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.442 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.441 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1qvr | ANP | Chaperone protein ClpB | / | 0.441 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.441 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.441 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.441 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.441 | |
| 3k5h | ATP | Phosphoribosyl-aminoimidazole carboxylase | / | 0.441 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.440 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.440 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.440 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.440 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.440 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.440 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.440 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.440 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.440 |