sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.782 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.758 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.737 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.737 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.549 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.546 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.523 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.519 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.507 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.506 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.506 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.500 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.497 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.496 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.494 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.492 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.490 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.490 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.490 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.489 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.488 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.487 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.484 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.484 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.484 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.483 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.483 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.483 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.482 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.480 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.480 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.479 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.478 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.477 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.472 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.471 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 3e6e | DCS | Alanine racemase | / | 0.471 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.471 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.466 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.466 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.466 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.466 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.465 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4jic | FMN | GTN Reductase | / | 0.465 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.463 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.462 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.461 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.461 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.460 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.460 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.459 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.458 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.458 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.457 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.456 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4e2y | JHZ | Methyltransferase | / | 0.456 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.456 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.453 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.452 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.452 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.452 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.451 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.451 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.450 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.450 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.450 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.449 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3eks | CY9 | Actin-5C | / | 0.449 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.449 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.449 | |
| 5c3r | HMU | Thymine dioxygenase | / | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.448 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.448 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.447 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.447 | |
| 2po3 | T4K | 4-dehydrase | / | 0.447 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.447 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3qsa | TA7 | Anthranilate phosphoribosyltransferase | / | 0.446 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.445 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.445 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.445 | |
| 2ylt | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.444 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.444 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.444 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.443 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.443 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.443 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4lut | DCS | Alanine racemase | / | 0.443 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.442 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.442 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.442 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.442 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.442 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.441 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.441 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.441 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.441 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.441 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.440 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.440 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.440 |