Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 1.000 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.608 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.605 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.604 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.596 | |
| 2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.595 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.594 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.590 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.589 | |
| 1q8t | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.582 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.577 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.571 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.566 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.560 | |
| 2f7z | 6EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.559 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.556 | |
| 3zo4 | QWI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.553 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.552 | |
| 2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.552 | |
| 2uw5 | GVN | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.540 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.538 | |
| 3ow3 | SMY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.538 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.536 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.535 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.534 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.525 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.524 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.516 | |
| 4iay | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.516 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.515 | |
| 2gnl | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.515 | |
| 2gnf | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.514 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.514 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.511 | |
| 1jbp | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.510 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.510 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.509 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.509 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.508 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.508 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.508 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.508 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.508 | |
| 2vo0 | M03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.507 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.507 | |
| 1veb | I05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.506 | |
| 4oti | MI1 | Serine/threonine-protein kinase N1 | / | 0.505 | |
| 1xha | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.502 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.502 | |
| 3ncz | 3NC | Rho-associated protein kinase 1 | 2.7.11.1 | 0.502 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.502 | |
| 1sve | I01 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.501 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.501 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.501 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.500 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.500 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.499 | |
| 2vo3 | M04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.498 | |
| 4fv2 | EK5 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.498 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.497 | |
| 4iaz | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.497 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.496 | |
| 3v5w | 8PR | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.495 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.495 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.494 | |
| 2uw4 | L15 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.493 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.493 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.493 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.493 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.493 | |
| 1j1b | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.492 | |
| 4mk0 | 29X | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.492 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.491 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.491 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.490 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 3zo1 | SIJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.490 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.490 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.490 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.490 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.489 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 2f2u | M77 | Rho-associated protein kinase 2 | 2.7.11.1 | 0.488 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.488 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.488 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.487 | |
| 1rej | B1L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.486 | |
| 2c1a | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.486 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.486 | |
| 3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.485 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.485 | |
| 1bx6 | BA1 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.484 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.483 | |
| 4iak | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.483 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.482 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.482 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.481 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.481 | |
| 1jkl | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.480 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.480 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.480 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.479 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.479 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.479 | |
| 4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.479 | |
| 1w8c | N69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.478 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.478 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.478 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.477 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.477 | |
| 4gv1 | 0XZ | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.477 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.477 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.476 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.476 | |
| 1q99 | ANP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.475 | |
| 1svh | I08 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.475 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.475 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.475 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.475 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 1xh6 | R94 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 3bwj | ARX | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 3agl | A03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.472 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.472 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.471 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.471 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.470 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.470 | |
| 5dnr | ATP | Aurora kinase A | 2.7.11.1 | 0.470 | |
| 1xh9 | R69 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.469 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.469 | |
| 4yxs | EMU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.469 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.468 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.467 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.467 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.466 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.466 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.466 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 2etr | Y27 | Rho-associated protein kinase 1 | 2.7.11.1 | 0.465 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.465 | |
| 3eb0 | DRK | Uncharacterized protein | / | 0.465 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.465 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.464 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.464 | |
| 2uw6 | GVO | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.463 | |
| 4ivb | 1J5 | Tyrosine-protein kinase JAK1 | / | 0.463 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.462 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.462 | |
| 1q24 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 4dh5 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 4f9c | 0SX | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.462 | |
| 1wc4 | APC | Adenylate cyclase | / | 0.461 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.461 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.460 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.460 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.460 | |
| 4ifc | ADP | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.460 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.459 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.458 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.458 | |
| 5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.458 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.457 | |
| 2z7q | ACP | Ribosomal protein S6 kinase alpha-1 | 2.7.11.1 | 0.457 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.457 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.457 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4f9b | 0SY | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.456 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.456 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.456 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.455 | |
| 1xh8 | R55 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.455 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.455 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.455 | |
| 4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1q3d | STU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 1yt9 | OIS | Gag-Pol polyprotein | / | 0.454 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.454 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.454 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.454 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3hzi | ATP | Serine/threonine-protein kinase toxin HipA | / | 0.453 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.453 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.452 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3o7l | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3tku | M77 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.452 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.452 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.452 | |
| 4i5c | C5I | Tyrosine-protein kinase JAK1 | / | 0.452 | |
| 4ye3 | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.451 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.450 | |
| 2c6l | DT4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 2gci | MRR | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.450 | |
| 2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4j99 | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.449 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.449 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.449 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.448 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.448 | |
| 4crs | AGS | Serine/threonine-protein kinase N2 | 2.7.11.13 | 0.448 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.448 | |
| 2a0c | CK9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.447 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 4e4n | 0NL | Tyrosine-protein kinase JAK1 | / | 0.447 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.446 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.446 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.445 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1hvr | XK2 | Gag-Pol polyprotein | / | 0.444 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.444 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3sa6 | F71 | Protease | / | 0.444 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1gqt | ACP | Ribokinase | / | 0.443 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.443 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3sd0 | TSK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.443 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.443 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3g51 | ANP | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.442 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.442 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.441 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.441 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.441 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.441 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.441 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.440 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.440 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3i2l | 2NC | Protease | / | 0.440 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.440 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.440 |