Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pmn | K51 | Protein kinase 7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pmn | K51 | Protein kinase 7 | / | 1.000 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.551 | |
| 2pml | ANP | Uncharacterized protein | / | 0.543 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.536 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.522 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.520 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.511 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.511 | |
| 3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.510 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.508 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.505 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.505 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.504 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.501 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.496 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.493 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.489 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.488 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.486 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.485 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.484 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.484 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.483 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.482 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.481 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.479 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.478 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.477 | |
| 3nup | 3NU | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.477 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 4ej4 | EJ4 | Delta-type opioid receptor | / | 0.477 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.476 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.476 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.475 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.475 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.474 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 3s0o | 50Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.473 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.473 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.471 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.470 | |
| 3c13 | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.470 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.470 | |
| 2ds1 | 1CD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.468 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.468 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.467 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.467 | |
| 3o0g | 3O0 | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.467 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.466 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.466 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.465 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.465 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.465 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.465 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1gii | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2uw4 | L15 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3rjc | 06Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.463 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.462 | |
| 3r8z | Z63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 1dm2 | HMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.461 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.461 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.460 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.460 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.460 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3sw7 | 19K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.460 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.460 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.459 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 2bhe | BRY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.458 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.458 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.457 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.457 | |
| 2a0c | CK9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.457 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.457 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.457 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.456 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3qru | X19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.455 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.455 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.454 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.454 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1pye | PM1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2c6o | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.453 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.453 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.452 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3rdq | DTB | Streptavidin | / | 0.452 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.451 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.451 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.451 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.451 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4lyn | 1YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.450 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.450 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.450 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.449 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.449 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.449 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.449 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.449 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.448 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.448 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2dwp | ACP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.448 | |
| 2r3l | SCW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.448 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.448 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4g3s | UD1 | Bifunctional protein GlmU | / | 0.448 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4oti | MI1 | Serine/threonine-protein kinase N1 | / | 0.448 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.448 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.447 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.447 | |
| 3qai | XNN | Ketohexokinase | / | 0.447 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.447 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.447 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.446 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2q55 | MU0 | Protease | / | 0.446 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.446 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.446 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.446 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1pxo | CK7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.445 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 3pvu | QRW | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.445 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.445 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 4e9a | QAP | Peptide deformylase | / | 0.445 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4fkq | 42K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1osv | CHC | Bile acid receptor | / | 0.444 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.444 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.444 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.443 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.443 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3r1y | X76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.443 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.442 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.442 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3nc9 | TR3 | Ketohexokinase | / | 0.442 | |
| 3qw2 | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.442 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.442 | |
| 3ti1 | B49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 4c61 | LMM | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.442 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.442 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.442 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 1e1x | NW1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.441 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.441 | |
| 2v52 | LAB | Actin, alpha skeletal muscle | / | 0.441 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.441 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3r6x | X84 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.440 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.440 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.440 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.440 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3u9e | COA | Lmo1369 protein | / | 0.440 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4d58 | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.440 |