sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2e15 | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2e15 | SAH | Diphthine synthase | / | 1.000 | |
| 2e17 | SAH | Diphthine synthase | / | 0.808 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.777 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.777 | |
| 2owu | SAH | Diphthine synthase | / | 0.772 | |
| 2hut | SAH | Diphthine synthase | / | 0.764 | |
| 2dsi | SAH | Diphthine synthase | / | 0.761 | |
| 2owk | SAH | Diphthine synthase | / | 0.749 | |
| 2p6i | SAH | Diphthine synthase | / | 0.730 | |
| 2z6r | SAH | Diphthine synthase | / | 0.728 | |
| 2owg | SAH | Diphthine synthase | / | 0.723 | |
| 2eeq | SAH | Diphthine synthase | / | 0.722 | |
| 2huq | SAH | Diphthine synthase | / | 0.722 | |
| 2e8r | SAH | Diphthine synthase | / | 0.717 | |
| 2p5c | SAH | Diphthine synthase | / | 0.712 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.709 | |
| 2p9d | SAH | Diphthine synthase | / | 0.697 | |
| 2dek | SAH | Diphthine synthase | / | 0.695 | |
| 2e07 | SAH | Diphthine synthase | / | 0.692 | |
| 2emu | SAH | Diphthine synthase | / | 0.692 | |
| 2pck | SAH | Diphthine synthase | / | 0.691 | |
| 2dsh | SAH | Diphthine synthase | / | 0.690 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.687 | |
| 2huv | SAH | Diphthine synthase | / | 0.686 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.680 | |
| 2p5f | SAH | Diphthine synthase | / | 0.677 | |
| 2e4n | SAH | Diphthine synthase | / | 0.672 | |
| 2dsg | SAH | Diphthine synthase | / | 0.670 | |
| 2el3 | SAH | Diphthine synthase | / | 0.670 | |
| 2dxx | SAH | Diphthine synthase | / | 0.669 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.667 | |
| 2emr | SAH | Diphthine synthase | / | 0.667 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.660 | |
| 2ehl | SAH | Diphthine synthase | / | 0.659 | |
| 2eni | SAH | Diphthine synthase | / | 0.657 | |
| 2p6l | SAH | Diphthine synthase | / | 0.657 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.656 | |
| 2eld | SAH | Diphthine synthase | / | 0.655 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.654 | |
| 1vce | SAH | Diphthine synthase | / | 0.652 | |
| 2e08 | SAH | Diphthine synthase | / | 0.652 | |
| 2e7r | SAH | Diphthine synthase | / | 0.651 | |
| 2e8h | SAH | Diphthine synthase | / | 0.649 | |
| 2egb | SAH | Diphthine synthase | / | 0.641 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.639 | |
| 2pca | SAH | Diphthine synthase | / | 0.639 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.638 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.634 | |
| 1wng | SAH | Diphthine synthase | / | 0.633 | |
| 2p2x | SAH | Diphthine synthase | / | 0.628 | |
| 2p6d | SAH | Diphthine synthase | / | 0.628 | |
| 2ele | SAH | Diphthine synthase | / | 0.626 | |
| 2p6k | SAH | Diphthine synthase | / | 0.625 | |
| 2ejj | SAH | Diphthine synthase | / | 0.619 | |
| 2el0 | SAH | Diphthine synthase | / | 0.618 | |
| 2ejk | SAH | Diphthine synthase | / | 0.617 | |
| 2owv | SAH | Diphthine synthase | / | 0.616 | |
| 2pci | SAH | Diphthine synthase | / | 0.610 | |
| 2pcg | SAH | Diphthine synthase | / | 0.601 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.600 | |
| 2egs | SAH | Diphthine synthase | / | 0.600 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.592 | |
| 2dxv | SAH | Diphthine synthase | / | 0.592 | |
| 2e16 | SAH | Diphthine synthase | / | 0.583 | |
| 2pcm | SAH | Diphthine synthase | / | 0.581 | |
| 2eka | SAH | Diphthine synthase | / | 0.578 | |
| 2ejz | SAH | Diphthine synthase | / | 0.575 | |
| 2pch | SAH | Diphthine synthase | / | 0.575 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.572 | |
| 2owf | SAH | Diphthine synthase | / | 0.572 | |
| 2hux | SAH | Diphthine synthase | / | 0.564 | |
| 2dxw | SAH | Diphthine synthase | / | 0.560 | |
| 2e8s | SAH | Diphthine synthase | / | 0.550 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.548 | |
| 2egl | SAH | Diphthine synthase | / | 0.533 | |
| 2e8q | SAH | Diphthine synthase | / | 0.519 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.518 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.511 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.507 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.495 | |
| 2en5 | SAH | Diphthine synthase | / | 0.489 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.488 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.488 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.483 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.478 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.478 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.477 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.474 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.474 | |
| 5dp2 | NAP | CurF | / | 0.474 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.473 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.473 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.472 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.472 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.471 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.471 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.471 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.470 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.469 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.468 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.468 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.468 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.468 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.468 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.467 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.467 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.465 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.463 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.463 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.463 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.462 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.461 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.461 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.460 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.460 | |
| 3a3g | DLZ | Lumazine protein | / | 0.459 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.459 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.459 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.458 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.458 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.458 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.457 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.457 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.457 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.457 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.457 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.456 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.456 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.456 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.456 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.456 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.456 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.455 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.455 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.455 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.454 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.454 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.453 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.453 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.453 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.452 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.452 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.452 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.451 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.451 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.451 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.451 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.451 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.450 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.450 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.450 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.450 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.450 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.449 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.449 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.449 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.449 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.449 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.449 | |
| 2p3b | 3TL | V-1 protease | / | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.449 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.449 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.449 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 4irn | FAD | AnaB | / | 0.449 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.448 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.448 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.448 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.448 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.448 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.447 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.447 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.447 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.446 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.446 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.446 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.445 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.445 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2y3s | TIR | TamL | / | 0.445 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.445 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.444 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.444 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.444 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 3a3b | RBF | Lumazine protein | / | 0.444 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.444 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.444 | |
| 4qec | NAP | ElxO | / | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.443 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.443 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.443 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.443 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.443 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.442 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.442 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.442 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.442 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.442 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.442 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.442 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.442 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.441 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.441 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.441 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.441 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.441 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.441 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.440 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.440 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3e39 | FMN | Nitroreductase | / | 0.440 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.440 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.440 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3vth | AP2 | Carbamoyltransferase | / | 0.440 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.440 |