sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dv4 | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2dv4 | SAH | Diphthine synthase | / | 1.000 | |
| 2dsg | SAH | Diphthine synthase | / | 0.852 | |
| 1wng | SAH | Diphthine synthase | / | 0.838 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.819 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.817 | |
| 2dxv | SAH | Diphthine synthase | / | 0.808 | |
| 2el0 | SAH | Diphthine synthase | / | 0.802 | |
| 2dsi | SAH | Diphthine synthase | / | 0.801 | |
| 2eni | SAH | Diphthine synthase | / | 0.789 | |
| 2dxw | SAH | Diphthine synthase | / | 0.771 | |
| 2eeq | SAH | Diphthine synthase | / | 0.769 | |
| 2e8q | SAH | Diphthine synthase | / | 0.765 | |
| 2ejk | SAH | Diphthine synthase | / | 0.765 | |
| 2emu | SAH | Diphthine synthase | / | 0.761 | |
| 2p6k | SAH | Diphthine synthase | / | 0.761 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.759 | |
| 2emr | SAH | Diphthine synthase | / | 0.748 | |
| 2hux | SAH | Diphthine synthase | / | 0.737 | |
| 2e17 | SAH | Diphthine synthase | / | 0.733 | |
| 2p5c | SAH | Diphthine synthase | / | 0.731 | |
| 2z6r | SAH | Diphthine synthase | / | 0.723 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.720 | |
| 2e8s | SAH | Diphthine synthase | / | 0.718 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.717 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.709 | |
| 2ehl | SAH | Diphthine synthase | / | 0.707 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.703 | |
| 2p6d | SAH | Diphthine synthase | / | 0.701 | |
| 2pca | SAH | Diphthine synthase | / | 0.701 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.700 | |
| 2pcm | SAH | Diphthine synthase | / | 0.700 | |
| 2e8h | SAH | Diphthine synthase | / | 0.698 | |
| 2p6i | SAH | Diphthine synthase | / | 0.696 | |
| 2e07 | SAH | Diphthine synthase | / | 0.691 | |
| 2egs | SAH | Diphthine synthase | / | 0.690 | |
| 2owu | SAH | Diphthine synthase | / | 0.687 | |
| 2ejj | SAH | Diphthine synthase | / | 0.685 | |
| 2huv | SAH | Diphthine synthase | / | 0.682 | |
| 2p2x | SAH | Diphthine synthase | / | 0.678 | |
| 2dxx | SAH | Diphthine synthase | / | 0.677 | |
| 2egl | SAH | Diphthine synthase | / | 0.672 | |
| 2p9d | SAH | Diphthine synthase | / | 0.672 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.671 | |
| 2en5 | SAH | Diphthine synthase | / | 0.669 | |
| 2dsh | SAH | Diphthine synthase | / | 0.668 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.668 | |
| 2p6l | SAH | Diphthine synthase | / | 0.666 | |
| 2e7r | SAH | Diphthine synthase | / | 0.663 | |
| 2pch | SAH | Diphthine synthase | / | 0.662 | |
| 2owg | SAH | Diphthine synthase | / | 0.661 | |
| 2pck | SAH | Diphthine synthase | / | 0.661 | |
| 2p5f | SAH | Diphthine synthase | / | 0.659 | |
| 2e4n | SAH | Diphthine synthase | / | 0.657 | |
| 2huq | SAH | Diphthine synthase | / | 0.652 | |
| 1vce | SAH | Diphthine synthase | / | 0.649 | |
| 2dek | SAH | Diphthine synthase | / | 0.648 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.648 | |
| 2eka | SAH | Diphthine synthase | / | 0.648 | |
| 2e08 | SAH | Diphthine synthase | / | 0.641 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.637 | |
| 2eld | SAH | Diphthine synthase | / | 0.637 | |
| 2e15 | SAH | Diphthine synthase | / | 0.635 | |
| 2pcg | SAH | Diphthine synthase | / | 0.634 | |
| 2e16 | SAH | Diphthine synthase | / | 0.632 | |
| 2owv | SAH | Diphthine synthase | / | 0.632 | |
| 2hut | SAH | Diphthine synthase | / | 0.631 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.630 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.628 | |
| 2owk | SAH | Diphthine synthase | / | 0.625 | |
| 2ele | SAH | Diphthine synthase | / | 0.621 | |
| 2pci | SAH | Diphthine synthase | / | 0.617 | |
| 2egb | SAH | Diphthine synthase | / | 0.607 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.602 | |
| 2e8r | SAH | Diphthine synthase | / | 0.587 | |
| 2el3 | SAH | Diphthine synthase | / | 0.586 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.581 | |
| 2owf | SAH | Diphthine synthase | / | 0.564 | |
| 2ejz | SAH | Diphthine synthase | / | 0.556 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.496 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.495 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.492 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.489 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.486 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.484 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.480 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.479 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.476 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.475 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.474 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.473 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.473 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.472 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.471 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.470 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.470 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.470 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.469 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.469 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.468 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.466 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.466 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.465 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.465 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.465 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.464 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.464 | |
| 5dp2 | NAP | CurF | / | 0.464 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.463 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.463 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.463 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.463 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.463 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.463 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.462 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.462 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.462 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.461 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.461 | |
| 4xr9 | NAD | CalS8 | / | 0.461 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.460 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.460 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.460 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.460 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.459 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.459 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.459 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.459 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.459 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.459 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.459 | |
| 3wag | TYD | Glycosyltransferase | / | 0.459 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.459 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2y3s | TIR | TamL | / | 0.458 | |
| 3a3g | DLZ | Lumazine protein | / | 0.458 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.457 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.457 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.457 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.457 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.457 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.457 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.457 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.457 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.455 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.455 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.455 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.454 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.454 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.454 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.454 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.454 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.453 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.453 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.453 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.453 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.453 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.453 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.452 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.451 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.451 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.451 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.451 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.451 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.450 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.450 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.449 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.449 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.449 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.449 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.449 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.449 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.448 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.448 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.448 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.448 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.447 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.447 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.447 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.447 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.447 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.447 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.447 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.446 | |
| 1eio | GCH | Gastrotropin | / | 0.446 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.446 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.446 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.446 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.445 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.444 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.443 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.443 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.443 | |
| 4irn | FAD | AnaB | / | 0.443 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.443 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.442 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.442 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.442 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.442 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.441 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.441 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.441 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 4qec | NAP | ElxO | / | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.441 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.440 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.440 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.440 |