sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ag0 | TPP | Benzaldehyde lyase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ag0 | TPP | Benzaldehyde lyase | / | 1.000 | |
| 2uz1 | TPP | Benzaldehyde lyase | / | 0.621 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.577 | |
| 3iaf | TPP | Benzaldehyde lyase | / | 0.531 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.514 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.512 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.511 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.511 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.503 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.498 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.498 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.498 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.497 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.496 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.495 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.492 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.491 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.489 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.489 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.489 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.489 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.489 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.488 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.487 | |
| 2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.487 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.484 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.482 | |
| 5ej7 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.481 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.479 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.476 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.475 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 3r95 | ACO | MccE protein | / | 0.475 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.474 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.474 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.473 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.472 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.471 | |
| 5ej5 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.471 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.470 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.469 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.468 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.467 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.467 | |
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 0.466 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.466 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.465 | |
| 3ln1 | CEL | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.465 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.464 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.464 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.463 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.463 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.462 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.462 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.462 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.462 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.462 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.462 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.462 | |
| 1ovm | TPP | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.461 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.461 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.461 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.461 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.461 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.460 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.460 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.458 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.458 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.458 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.457 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.457 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.457 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.457 | |
| 1kek | HTL | Pyruvate synthase | / | 0.456 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.456 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.456 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.456 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.456 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.456 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.455 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.455 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.455 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.454 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.454 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit alpha | / | 0.454 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit beta | / | 0.454 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.453 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.453 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.453 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.452 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.452 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.452 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.452 | |
| 2nr4 | FMN | Conserved protein | / | 0.452 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.452 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.452 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.452 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1pvd | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.451 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.451 | |
| 2egl | SAH | Diphthine synthase | / | 0.451 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.451 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.451 | |
| 3a3b | RBF | Lumazine protein | / | 0.450 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.450 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.449 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.449 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.449 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.449 | |
| 5a3b | APR | SIR2 family protein | / | 0.449 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1mma | ADP | Myosin-2 heavy chain | / | 0.448 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.448 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.448 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.448 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.447 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.447 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4nte | FAD | DepH | / | 0.447 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.447 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.447 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.446 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.446 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.446 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.446 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4u7w | NDP | MxaA | / | 0.446 | |
| 5a3c | NAD | SIR2 family protein | / | 0.446 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.445 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.445 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.445 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.445 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.444 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2bxm | IMN | Serum albumin | / | 0.444 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 3e8r | 615 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.444 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.444 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.444 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2kce | D16 | Thymidylate synthase | / | 0.443 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.443 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.443 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.443 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.442 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2vk4 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.442 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.442 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.442 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3lu8 | IQX | Serum albumin | / | 0.442 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.442 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.442 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 1l4k | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.441 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.441 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.441 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.441 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.441 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.441 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.441 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1iqe | XMB | Coagulation factor X | 3.4.21.6 | 0.440 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.440 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2xvv | 9DN | Serum albumin | / | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4l1f | COS | Acyl-CoA dehydrogenase domain protein | / | 0.440 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.440 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |