sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1mu8 | CDB | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 1.000 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.775 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.775 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.725 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.704 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.680 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.658 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.655 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.649 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.648 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.645 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.643 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.639 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.639 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.637 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.637 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.634 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.633 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.631 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.626 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.626 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.625 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.624 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.621 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.614 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.611 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.610 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.608 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.606 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.603 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.601 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.600 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.599 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.598 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.598 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.594 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.594 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.594 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.593 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.593 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.592 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.589 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.588 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.588 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.587 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.586 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.585 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.583 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.583 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.581 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.578 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.578 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.577 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.576 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.575 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.575 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.573 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.573 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.573 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.569 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.569 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.568 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.568 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.568 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.565 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.565 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.565 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.564 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.563 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.562 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.561 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.559 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.556 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.555 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.553 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.552 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.551 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.550 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.550 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.549 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.546 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.543 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.543 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.542 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.542 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.542 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.541 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.540 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.536 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.534 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.531 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.531 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.530 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.530 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.529 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.526 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.526 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.526 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.523 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.519 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.518 | |
| 1nt1 | T76 | Prothrombin | 3.4.21.5 | 0.512 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.511 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.511 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.510 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.507 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.506 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.503 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.500 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.498 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.494 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.489 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.484 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.481 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.478 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.478 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.478 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.477 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.477 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.476 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.473 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.473 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2j4l | UTP | Uridylate kinase | 2.7.4.22 | 0.472 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.472 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.472 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.471 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.469 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.469 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.468 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.468 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.467 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.467 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.467 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.467 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.467 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.466 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.466 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.466 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.465 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 3sor | O58 | Coagulation factor XI | 3.4.21.27 | 0.463 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.462 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.461 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.461 | |
| 2nr4 | FMN | Conserved protein | / | 0.460 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.459 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.459 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.459 | |
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 | 0.458 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.458 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.457 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.457 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.457 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.457 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.456 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.456 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.456 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.455 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.455 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.455 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.455 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.454 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.454 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.453 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.453 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.453 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.452 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.452 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.452 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.452 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.451 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.451 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.451 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.451 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.450 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.450 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.450 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.450 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.449 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.449 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.449 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.448 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 3bnk | FMN | Flavoredoxin | / | 0.448 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.448 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.448 | |
| 5la6 | GDP | Tubulin beta-2B chain | / | 0.448 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.447 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.447 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.447 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4e2y | JHZ | Methyltransferase | / | 0.447 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 4xr9 | NAD | CalS8 | / | 0.447 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.446 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.446 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.446 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.446 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.446 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 1lce | TMF | Thymidylate synthase | / | 0.445 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.445 | |
| 3pft | FMN | Flavin reductase | / | 0.445 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.445 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.444 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.444 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.444 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.444 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.444 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.444 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.444 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.444 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.444 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1p4a | PCP | Pur operon repressor | / | 0.443 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3zg6 | APR | NAD-dependent protein deacetylase sirtuin-6 | 3.5.1 | 0.443 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.443 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.442 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.442 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.442 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.442 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.441 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.441 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.441 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 2q0l | NAP | Thioredoxin reductase | 1.8.1.9 | 0.440 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2viv | VG2 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.440 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.440 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.440 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.440 |