sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1d2s | DHT | Sex hormone-binding globulin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1d2s | DHT | Sex hormone-binding globulin | / | 1.000 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.632 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.573 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.516 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 1lho | AOM | Sex hormone-binding globulin | / | 0.486 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.486 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.485 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.482 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.480 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.480 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.480 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.478 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.478 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.477 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.476 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.473 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.473 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 3qly | 55V | Uncharacterized protein | / | 0.472 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.471 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.471 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.471 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.471 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.470 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.469 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.468 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.468 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.468 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.468 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.467 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.467 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.467 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.467 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.467 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.466 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.466 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.466 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.466 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.466 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.466 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.466 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.465 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.465 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.465 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.465 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4lts | LTS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.465 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4g3s | UD1 | Bifunctional protein GlmU | / | 0.464 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.464 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.463 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.463 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.463 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.462 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.461 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.461 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.460 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2wpx | ACO | Orf14 | / | 0.460 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.460 | |
| 4m6p | 20R | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.460 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.460 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.459 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.459 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.459 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.459 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 1lhn | AON | Sex hormone-binding globulin | / | 0.458 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.458 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.458 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.458 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.457 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.457 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.457 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.457 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.457 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.456 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.456 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.456 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.456 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.456 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.456 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.455 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.455 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.455 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.455 | |
| 4kfo | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.455 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.455 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.455 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.454 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.454 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.454 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.454 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.454 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.454 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.454 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.453 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.453 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.453 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 3wgw | T2B | Proliferating cell nuclear antigen | / | 0.453 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.453 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.452 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.452 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.452 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.452 | |
| 3rus | ADP | Chaperonin | / | 0.452 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.452 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.452 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.452 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.451 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.451 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.451 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.451 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.451 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.450 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.450 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
| 4kfn | 1QR | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.450 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.450 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1m9r | INE | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.449 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.449 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.449 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.449 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4kfp | 1R7 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.449 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.449 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.449 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.448 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.448 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.448 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.448 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.448 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.448 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.448 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.448 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.448 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.448 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.448 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.448 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.447 | |
| 1ung | ALH | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.447 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.447 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.447 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.447 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 3eej | 53R | Uncharacterized protein | / | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.447 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.447 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.447 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.447 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.447 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.447 | |
| 4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.447 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.447 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.447 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.446 | |
| 1wvy | STU | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.446 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.446 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.446 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.446 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.446 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.446 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.446 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.446 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.445 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.445 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.445 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.445 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.445 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.445 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.445 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.444 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.444 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.444 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.444 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 4qin | SG8 | Smoothened homolog | / | 0.444 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.443 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.443 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 2jko | BIJ | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 3w0n | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.443 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.443 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.443 | |
| 4pd6 | URI | Nucleoside permease | / | 0.443 | |
| 4zol | ACP | Tubulin tyrosine ligase | / | 0.443 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.443 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.442 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.442 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.442 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.442 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.442 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 4v12 | POG | MaoC like domain protein | / | 0.442 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.441 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 2pin | 4HY | Thyroid hormone receptor beta | / | 0.441 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3eek | 53S | Uncharacterized protein | / | 0.441 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.441 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.441 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.441 | |
| 4okx | 198 | Androgen receptor | / | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.440 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2oxt | SAM | Genome polyprotein | / | 0.440 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.440 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.440 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.440 |