sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 1.430 | |
| 3sx2 | NAD | Uncharacterized protein | / | 1.307 | |
| 3tsc | NAD | Uncharacterized protein | / | 1.231 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 1.215 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 1.034 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 1.026 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.951 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.942 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.932 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.930 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.930 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.911 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.908 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.907 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.905 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.903 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.902 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.900 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.895 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.892 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.890 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.888 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.887 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.886 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.885 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.882 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.880 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.877 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.872 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.871 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.865 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.863 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.861 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.859 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.859 | |
| 3sju | NDP | Keto reductase | / | 0.857 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.855 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.848 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.847 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.846 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.845 | |
| 1iy8 | NAD | Levodione reductase | / | 0.844 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.843 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.843 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.843 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.842 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.841 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.840 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.838 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.836 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.833 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.832 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.828 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.826 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.822 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.822 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.821 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.819 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.818 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.817 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.817 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.817 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.814 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.813 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.813 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.812 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.811 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.807 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.806 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.806 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.804 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.802 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.802 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.801 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.801 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.800 | |
| 4qec | NAP | ElxO | / | 0.800 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.800 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.799 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.798 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.797 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.793 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.793 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.793 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.789 | |
| 3mje | NDP | AmphB | / | 0.788 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.788 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.786 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.782 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.782 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.780 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.780 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.780 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.780 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.777 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.777 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.777 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.777 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.776 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.776 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.775 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.775 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.772 | |
| 1sny | NAP | LD36273p | / | 0.770 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.769 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.769 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.769 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.769 | |
| 4qed | NAP | ElxO | / | 0.767 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.766 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.765 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.764 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.763 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.763 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.763 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.761 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.760 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.760 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.760 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.759 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.759 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.758 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.757 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.757 | |
| 4u7w | NDP | MxaA | / | 0.757 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.754 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.753 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.752 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.751 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.751 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.750 | |
| 4kwh | NAP | Reductase homolog | / | 0.750 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.749 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.748 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.748 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.746 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.745 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.744 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.743 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.742 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.742 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.742 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.741 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.740 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.739 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.738 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.737 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.735 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.734 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.733 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.733 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.732 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.732 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.732 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.730 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.730 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.730 | |
| 1wy7 | SAH | Uncharacterized protein | / | 0.728 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.728 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.727 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.726 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.725 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.725 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.725 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.724 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.723 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.721 | |
| 3ec7 | NAD | Inositol 2-dehydrogenase | / | 0.721 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.721 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.718 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.717 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.716 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.715 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.714 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.714 | |
| 3uce | NDP | Dehydrogenase | / | 0.714 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.712 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.711 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.710 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.710 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.710 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.709 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.709 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.708 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.707 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 3kkj | FAD | Renalase | / | 0.706 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.706 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.705 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.705 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.704 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.704 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.704 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.703 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.703 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.701 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.701 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.700 | |
| 3v8v | SAM | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.700 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.699 | |
| 4fp9 | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.698 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.697 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.696 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.695 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.695 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.694 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.692 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.692 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.690 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.689 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 1eg2 | MTA | Modification methylase RsrI | 2.1.1.72 | 0.688 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.687 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.687 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 3tos | SAH | CalS11 | / | 0.686 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.685 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.685 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.684 | |
| 3bmo | NAP | Pteridine reductase | / | 0.684 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.681 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.679 | |
| 1la2 | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.678 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.678 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.678 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.677 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.676 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.676 | |
| 3qvt | NAI | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.676 | |
| 4hxy | NDP | Plm1 | / | 0.676 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.676 | |
| 3b1j | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.675 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.674 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.674 | |
| 4usr | FAD | Monooxygenase | / | 0.674 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.673 | |
| 1y9d | FAD | Pyruvate oxidase | 1.2.3.3 | 0.673 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.673 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.672 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.672 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.670 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.669 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.669 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.669 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.669 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.669 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.667 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.665 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.665 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.664 | |
| 3qw2 | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.664 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.664 | |
| 4gf5 | SAH | CalS11 | / | 0.664 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.663 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.663 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.663 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.662 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.662 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.661 | |
| 3abi | NAD | Uncharacterized protein | / | 0.661 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.661 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.660 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.659 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.659 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.659 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.659 | |
| 1sc6 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.658 | |
| 4c03 | SFG | Protein arginine N-methyltransferase 6 | / | 0.657 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.657 | |
| 1p1i | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.656 | |
| 1uay | ADN | Oxidoreductase | / | 0.656 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.655 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.655 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.654 | |
| 4yuv | S4M | Spermidine synthase, putative | / | 0.654 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.653 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.653 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.653 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.652 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.652 | |
| 2ixb | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.652 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.652 | |
| 4clo | NAP | Pteridine reductase | / | 0.652 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.651 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.651 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.651 | |
| 4dkj | SAH | Cytosine-specific methyltransferase | / | 0.651 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.650 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.650 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.650 |