sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5xr8 | FMN | Cannabinoid receptor 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5xr8 | FMN | Cannabinoid receptor 1 | / | 1.000 | |
| 5xra | FMN | Cannabinoid receptor 1 | / | 0.564 | |
| 1aku | FMN | Flavodoxin | / | 0.526 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.525 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.521 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.511 | |
| 4fx2 | FMN | Flavodoxin | / | 0.509 | |
| 3f6r | FMN | Flavodoxin | / | 0.508 | |
| 1azl | FMN | Flavodoxin | / | 0.507 | |
| 1c7f | FMN | Flavodoxin | / | 0.507 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.505 | |
| 1wsb | FMN | Flavodoxin | / | 0.499 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1xyy | FMN | Flavodoxin | / | 0.490 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1j8q | FMN | Flavodoxin | / | 0.487 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.482 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.482 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.479 | |
| 1akw | FMN | Flavodoxin | / | 0.477 | |
| 3kaq | FMN | Flavodoxin | / | 0.477 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.476 | |
| 1j9z | FMN | NADPH--cytochrome P450 reductase | / | 0.475 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.474 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.472 | |
| 2fx2 | FMN | Flavodoxin | / | 0.471 | |
| 3eks | CY9 | Actin-5C | / | 0.471 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 4kxj | P34 | Nucleoprotein | / | 0.471 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.470 | |
| 1xyv | FMN | Flavodoxin | / | 0.470 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.469 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.468 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.468 | |
| 3esy | FMN | Flavodoxin | / | 0.467 | |
| 1j9g | FMN | Flavodoxin | / | 0.466 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.466 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.466 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.466 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.466 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.465 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.465 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.464 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.464 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.464 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 3ck7 | ACX | Starch-binding protein SusD | / | 0.463 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.463 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.463 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.463 | |
| 4oxx | FMN | Cindoxin | / | 0.463 | |
| 1bu5 | RBF | Flavodoxin | / | 0.462 | |
| 1ofv | FMN | Flavodoxin | / | 0.462 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3eku | CY9 | Actin-5C | / | 0.462 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.462 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.462 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.461 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.460 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.459 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.458 | |
| 2r5n | TPP | Transketolase 1 | / | 0.458 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.458 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.457 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.457 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.457 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.457 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.456 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.456 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.456 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.456 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.454 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.454 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.454 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.454 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.453 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.453 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.453 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.453 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.453 | |
| 4lut | DCS | Alanine racemase | / | 0.453 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.453 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.452 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.451 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.451 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.451 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.451 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.451 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.450 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.450 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.450 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.450 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.450 | |
| 4e2d | FMN | Dehydrogenase | / | 0.450 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.450 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.450 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.449 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.449 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.449 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.449 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.449 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.449 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.449 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.449 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.449 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.449 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.449 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.448 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.448 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.448 | |
| 2ejz | SAH | Diphthine synthase | / | 0.448 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.448 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.447 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.447 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.447 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.447 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.447 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.446 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.446 | |
| 2e07 | SAH | Diphthine synthase | / | 0.446 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.446 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.446 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.446 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.445 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.445 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.445 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.444 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.444 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.444 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2vuu | NAP | Nitrogen metabolite repression protein nmrA | / | 0.444 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.444 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.444 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.444 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.444 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.443 | |
| 1czn | FMN | Flavodoxin | / | 0.443 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.443 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.443 | |
| 3qvi | K95 | HAP protein | / | 0.443 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.443 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.443 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.443 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.442 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.442 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.442 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.442 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3ndj | JHZ | Methyltransferase | / | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.442 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.442 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.441 | |
| 1fx1 | FMN | Flavodoxin | / | 0.441 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.441 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 2cts | COA | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 2ewv | ADP | Twitching motility protein PilT | / | 0.441 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.441 | |
| 3kft | NAD | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1jf0 | CZH | Obelin | / | 0.440 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.440 | |
| 2hv9 | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.440 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4e2x | TYD | Methyltransferase | / | 0.440 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 |