sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 1.000 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.509 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.506 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.505 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.503 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.502 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.499 | |
| 2puh | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.497 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.496 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.494 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.490 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.490 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.490 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.490 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.485 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.484 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.483 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.483 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.482 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.480 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 4l8u | 9AZ | Serum albumin | / | 0.478 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.478 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.477 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.477 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.477 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.476 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.476 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.476 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.476 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.473 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.472 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.471 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.470 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.470 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.469 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.469 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.469 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.468 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.468 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.468 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.467 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.467 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.466 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.466 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.465 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.465 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.464 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.464 | |
| 3h1j | SMA | Cytochrome b | / | 0.464 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.464 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.464 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.464 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.463 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.463 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.463 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.463 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 2acw | UPG | Glycosyltransferase | / | 0.462 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.462 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.461 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.461 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.461 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.461 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.461 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.460 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.460 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.459 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.459 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.459 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.459 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.458 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.458 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.458 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.457 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.457 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.457 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.457 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.457 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.457 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.457 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.456 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.456 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.456 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.455 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.455 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.455 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.455 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.455 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.455 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.454 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.454 | |
| 3eel | 53T | Uncharacterized protein | / | 0.454 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.454 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.454 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 1osv | CHC | Bile acid receptor | / | 0.453 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.453 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.453 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.453 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.453 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.453 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.453 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 4l9q | 9TP | Serum albumin | / | 0.452 | |
| 4lb2 | DM5 | Serum albumin | / | 0.452 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.451 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.451 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.451 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.451 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.451 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.451 | |
| 4hdr | DMD | ArsB | / | 0.451 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.451 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.450 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.450 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.450 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.450 | |
| 4iah | 1DX | Alr2278 protein | / | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.449 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.449 | |
| 2qjy | SMA | Cytochrome b | / | 0.449 | |
| 2yiu | SMA | Cytochrome b | / | 0.449 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.449 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.449 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.449 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.448 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.448 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.448 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.448 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.448 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3qly | 55V | Uncharacterized protein | / | 0.448 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.448 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.447 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.447 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.447 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.447 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.447 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.447 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.447 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.447 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.447 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.446 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3fnu | 006 | HAP protein | / | 0.446 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.446 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.446 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.446 | |
| 4pd6 | URI | Nucleoside permease | / | 0.446 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.445 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.445 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.445 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.444 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.444 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.444 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.444 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.444 | |
| 3cxh | SMA | Cytochrome b | / | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.444 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3cx5 | SMA | Cytochrome b | / | 0.443 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.443 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.443 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.443 | |
| 4e70 | N7I | Coniferyl alcohol 9-O-methyltransferase | / | 0.443 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.443 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.443 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.442 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1ysx | 4EB | Serum albumin | / | 0.442 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.442 | |
| 2p15 | EZT | Estrogen receptor | / | 0.442 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.442 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.442 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.442 | |
| 4iae | 1DX | Alr2278 protein | / | 0.442 | |
| 4tqq | UQ1 | Reaction center protein L chain | / | 0.442 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.442 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.441 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.441 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.441 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.441 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.441 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.441 | |
| 4l4x | NDP | AmphI | / | 0.441 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 5l7d | CLR | Smoothened homolog | / | 0.441 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 1kb9 | SMA | Cytochrome b | / | 0.440 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1pp9 | SMA | Cytochrome b | / | 0.440 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.440 | |
| 2pnu | ENM | Androgen receptor | / | 0.440 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.440 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.440 | |
| 3q30 | D61 | Squalene synthase | 2.5.1.21 | 0.440 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.440 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.440 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.440 |