sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1i7m | CG | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1i7m | CG | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 1.000 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.620 | |
| 1i7c | MGB | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.612 | |
| 3dz4 | C8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.608 | |
| 3dz2 | A8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.593 | |
| 3h0w | N8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.575 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.566 | |
| 3h0v | M2T | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.518 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.508 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.507 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.507 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.505 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.504 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.504 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.493 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 2ejz | SAH | Diphthine synthase | / | 0.490 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.486 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.484 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.482 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.477 | |
| 4e32 | DWN | Methyltransferase | / | 0.477 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.475 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.474 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.472 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.472 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.472 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.471 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.470 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 3wb5 | 0B4 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.468 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.467 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.466 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.464 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.464 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.464 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.464 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.463 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.463 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.462 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.462 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.462 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.462 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.462 | |
| 5cfn | 2BA | Stimulator of interferon genes protein | / | 0.462 | |
| 3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.461 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.461 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.460 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.459 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.459 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.459 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2dsh | SAH | Diphthine synthase | / | 0.458 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.458 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.458 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.457 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.457 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.457 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.456 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.456 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.456 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.456 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.456 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.456 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.456 | |
| 1hi0 | GTP | RNA-directed RNA polymerase | 2.7.7.48 | 0.455 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3e4a | QIX | Insulin-degrading enzyme | 3.4.24.56 | 0.455 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.455 | |
| 1fml | RTL | Retinol dehydratase | / | 0.454 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.454 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.454 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.454 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.454 | |
| 4e2z | JHZ | Methyltransferase | / | 0.454 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.454 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.454 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.454 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.453 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2bqz | SAH | N-lysine methyltransferase KMT5A | / | 0.453 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.453 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.453 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.453 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.453 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.453 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.453 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.452 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.452 | |
| 4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 5dp2 | NAP | CurF | / | 0.452 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3e6e | DCS | Alanine racemase | / | 0.451 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.451 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.451 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 1e6z | NGO | Chitinase | / | 0.450 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.450 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.450 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.450 | |
| 2h8x | FMN | XenA | / | 0.450 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.450 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.450 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.449 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.449 | |
| 4br3 | U85 | Choline kinase alpha | 2.7.1.32 | 0.449 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.449 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4j7h | TRH | PCZA361.3 | / | 0.449 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.449 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.448 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.448 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.448 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.448 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.448 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.448 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 2iwh | ANP | Elongation factor 3A | / | 0.447 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.447 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.446 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.446 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.445 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.445 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.445 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.445 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.445 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.445 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.445 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.445 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.444 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.444 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.444 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.444 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.444 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.444 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.444 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.444 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.444 | |
| 3c1o | NAP | Eugenol synthase | / | 0.444 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 1lce | TMF | Thymidylate synthase | / | 0.443 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.443 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4j7g | TRH | PCZA361.3 | / | 0.443 | |
| 4y1b | NAP | AntE | / | 0.443 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.443 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.442 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.442 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3voi | RCB | Glucanase | / | 0.442 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.442 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 1bp0 | UMP | Thymidylate synthase | / | 0.441 | |
| 1gae | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.441 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2qe2 | 452 | Polyprotein | / | 0.441 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.441 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.441 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.441 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.441 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.441 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.440 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.440 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.440 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.440 | |
| 4aoa | IK2 | Beta-phenylalanine transaminase | 2.6.1 | 0.440 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.440 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 |