sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 1.000 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.492 | |
| 1osv | CHC | Bile acid receptor | / | 0.491 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.491 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.491 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.490 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.490 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.490 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.484 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.478 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.478 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.476 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.474 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.474 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.473 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.471 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.471 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.471 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.470 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.470 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.469 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.469 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.468 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.468 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.468 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.467 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.467 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.466 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.466 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.466 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.466 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.466 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.466 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.466 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.465 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.465 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.465 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.463 | |
| 2o3z | AI7 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.463 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.463 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.462 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.462 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.462 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.461 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.461 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.461 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.459 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.458 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.458 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.458 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.458 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.458 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.458 | |
| 4hjf | C2E | GGDEF family protein | / | 0.458 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.458 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.458 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.458 | |
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.457 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 2dph | NAD | Formaldehyde dismutase | / | 0.457 | |
| 2go4 | TUX | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.457 | |
| 2qhy | MZ1 | Gag-Pol polyprotein | / | 0.457 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1gqt | ACP | Ribokinase | / | 0.456 | |
| 2oxi | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.456 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.456 | |
| 3saa | 77F | Protease | / | 0.456 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.456 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.456 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.455 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.455 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.455 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.455 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.455 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.454 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.454 | |
| 2upj | U02 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.454 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.454 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.454 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.454 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.453 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.453 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.453 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.453 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.453 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.453 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.452 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.452 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.452 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.452 | |
| 3cyw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.452 | |
| 4upj | U04 | Gag-Pol polyprotein | / | 0.452 | |
| 1fgc | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1qbr | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.451 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.451 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.451 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.451 | |
| 3u9e | COA | Lmo1369 protein | / | 0.451 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.451 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.451 | |
| 1ajv | NMB | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.450 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.450 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.450 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.450 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.450 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.450 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.449 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.449 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.449 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.449 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.449 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.449 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.449 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4q36 | CO8 | Uncharacterized protein | / | 0.449 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.449 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1tf7 | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.448 | |
| 1u9i | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.448 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.448 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.448 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.448 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.448 | |
| 4njt | 017 | Protease | / | 0.448 | |
| 5ap7 | SVE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.448 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1ict | T44 | Transthyretin | / | 0.447 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.447 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.447 | |
| 2i0a | MUI | Protease | / | 0.447 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.447 | |
| 2oxt | SAM | Genome polyprotein | / | 0.447 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.447 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2wkz | 5AH | Gag-Pol polyprotein | / | 0.447 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.447 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.447 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4o7u | THF | Thymidylate synthase | / | 0.447 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.446 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.446 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.446 | |
| 3liv | E16 | Protease | / | 0.446 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.446 | |
| 3sjz | GNP | Translation initiation factor 2 subunit gamma | / | 0.446 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.446 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.446 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 4mqy | 2CW | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.446 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.446 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.445 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.445 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.445 | |
| 1tys | TMP | Thymidylate synthase | / | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.445 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.445 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.445 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 3mw9 | NAI | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.445 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3s5w | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.445 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.445 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.445 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.445 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.445 | |
| 4mfp | COA | Uncharacterized protein | / | 0.445 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.445 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.445 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.444 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.444 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.444 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.444 | |
| 2vrx | 447 | Aurora kinase B-A | 2.7.11.1 | 0.444 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.444 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.444 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.444 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 6upj | NIU | Gag-Pol polyprotein | / | 0.444 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.443 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.443 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.443 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.443 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3eky | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3ql6 | NIM | Lactoperoxidase | 1.11.1.7 | 0.443 | |
| 4phl | PIL | Phosphodiesterase | / | 0.443 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1bwa | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.442 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.442 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.442 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.442 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.442 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.442 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.442 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.442 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4c4o | NAD | SADH | / | 0.442 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.442 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.442 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.442 | |
| 5htx | ADP | Putative xylulose kinase | / | 0.442 | |
| 1ec1 | BEE | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.441 | |
| 1ivp | 1ZK | Gag-Pol polyprotein | / | 0.441 | |
| 1k2b | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.441 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.441 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2wl0 | 5AH | Gag-Pol polyprotein | / | 0.441 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 2xyf | G40 | Gag-Pol polyprotein | / | 0.441 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3pxv | FMN | Nitroreductase | / | 0.441 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3rus | ADP | Chaperonin | / | 0.441 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.441 | |
| 3vew | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.441 | |
| 4cx5 | HW8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4n9w | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.441 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.440 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.440 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.440 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.440 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.440 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.440 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.440 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3nxe | 2NC | Protease | / | 0.440 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.440 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 |