sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q3f | GNP | Ras-related GTP-binding protein D |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 1.000 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.528 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.526 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.520 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.519 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.515 | |
| 4y0v | GDP | ADP-ribosylation factor 1, putative | / | 0.515 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.514 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.513 | |
| 3r7w | GNP | GTP-binding protein GTR2 | / | 0.512 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.510 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.510 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.508 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.506 | |
| 3qe0 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.504 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.502 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.500 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.497 | |
| 4fid | GDP | G protein alpha subunit, putative | / | 0.496 | |
| 4g01 | GDP | Ras-related protein RABF2b | / | 0.496 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.495 | |
| 2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.495 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.495 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.494 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.494 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.494 | |
| 4ylg | GDP | ADP-ribosylation factor 1, putative | / | 0.493 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.491 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.491 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.488 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.488 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.484 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.483 | |
| 3tgp | GNP | GTPase HRas | / | 0.483 | |
| 1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.482 | |
| 1wdt | GTP | Elongation factor G (EF-G-2) | / | 0.481 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.481 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.478 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.477 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.477 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.476 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.476 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.476 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.475 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3r9x | GNP | GTPase Era | / | 0.474 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.474 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.474 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.473 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.471 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.471 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.469 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.469 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.468 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.468 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.467 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.467 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.467 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.466 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.466 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.466 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.466 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.466 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.464 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.463 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.463 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.463 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.463 | |
| 1eio | GCH | Gastrotropin | / | 0.462 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.462 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.462 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.462 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.461 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.461 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.461 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.461 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.460 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.460 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.460 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.460 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.459 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.459 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.459 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.458 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.458 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.458 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.457 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.457 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.457 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.457 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.456 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.456 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.456 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.456 | |
| 2rgg | GNP | GTPase HRas | / | 0.456 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.456 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.456 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.455 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1n1e | NDE | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.455 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.455 | |
| 4dja | FAD | (6-4) photolyase | / | 0.455 | |
| 4luc | GDP | GTPase KRas | / | 0.455 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.455 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.454 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.453 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.453 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.453 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.453 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.453 | |
| 4blr | UTP | NTPase P4 | / | 0.453 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.452 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.452 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.452 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.451 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.451 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.451 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.451 | |
| 4v02 | ATP | Site-determining protein | / | 0.451 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.450 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.450 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.450 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.450 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.450 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1u0h | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.449 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.449 | |
| 3dm5 | GDP | Signal recognition particle 54 kDa protein | / | 0.449 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.449 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.449 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.449 | |
| 5ftc | ADP | TPR domain protein | / | 0.449 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.448 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.448 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.448 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.448 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3ref | GDP | Rho family GTPase | / | 0.448 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4lpk | GDP | GTPase KRas | / | 0.448 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.447 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.447 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.447 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.447 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.447 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.447 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4xvq | GNP | GTPase HRas | / | 0.447 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.446 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.446 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.446 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.446 | |
| 3k8y | GNP | GTPase HRas | / | 0.446 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.446 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 3a37 | ADP | ATPase GET3 | / | 0.445 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.445 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.445 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.445 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.445 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.444 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 3a20 | FMN | FMN-binding protein | / | 0.444 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.444 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.444 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.444 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.444 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.444 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.443 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.443 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.443 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.443 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.443 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.443 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.443 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.443 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.443 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.442 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.442 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 4mkg | AP5 | Adenylate kinase | / | 0.442 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 5cyp | GSP | Septin-9 | / | 0.442 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 1gp2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.441 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.441 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4die | C5P | Cytidylate kinase | / | 0.441 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.441 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.441 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.441 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.440 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2qaj | AP5 | Adenylate kinase | / | 0.440 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.440 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.440 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4e5m | NAP | Phosphonate dehydrogenase | 1.20.1.1 | 0.440 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.440 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.440 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |