sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 1.000 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.762 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.665 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.660 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.636 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.628 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.627 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.622 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.616 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.615 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.610 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.610 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.607 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.604 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.595 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.587 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.586 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.579 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.578 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.569 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.558 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.551 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.528 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.526 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.526 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.522 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.521 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.520 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.519 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.519 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.511 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.510 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.510 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.508 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.507 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.506 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.504 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.499 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.496 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.495 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.494 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.493 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.490 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.490 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.486 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.485 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.485 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.485 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.484 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.484 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.482 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.482 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.480 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.477 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.476 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.476 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.475 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.475 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.474 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.474 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.474 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.474 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.474 | |
| 3gob | HXX | DdmC | / | 0.473 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.473 | |
| 1osv | CHC | Bile acid receptor | / | 0.472 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.472 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.472 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.472 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.472 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.470 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.470 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.469 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.469 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.468 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.468 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.468 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.467 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.467 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.466 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.466 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.465 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.465 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.464 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.464 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.464 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.464 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.464 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.463 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.463 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.463 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.462 | |
| 2yne | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.460 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.460 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.460 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.459 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.459 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.459 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.458 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.457 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.457 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.457 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.457 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.456 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.456 | |
| 2y3r | TRK | TamL | / | 0.456 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.456 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1eio | GCH | Gastrotropin | / | 0.455 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.455 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.455 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.454 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.454 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3h18 | PMS | Esterase/lipase | / | 0.454 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.454 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.453 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.453 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.453 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.452 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.452 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.451 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.451 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.451 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.451 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1yin | CM3 | Estrogen receptor | / | 0.450 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.450 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.450 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.450 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.450 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.449 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.449 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.449 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.449 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.449 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.449 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2iog | IOG | Estrogen receptor | / | 0.448 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.448 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.448 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.448 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.447 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.447 | |
| 2bxo | OPB | Serum albumin | / | 0.447 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.447 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.447 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.447 | |
| 4a30 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.447 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.447 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.447 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.446 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.446 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2pnu | ENM | Androgen receptor | / | 0.446 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.446 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3zuy | TCH | Transporter | / | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.445 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.445 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.445 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.445 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.444 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.444 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.444 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.444 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4okb | 198 | Androgen receptor | / | 0.444 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.444 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.444 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.443 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.443 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.443 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.443 | |
| 5l7d | CLR | Smoothened homolog | / | 0.443 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.442 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.442 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.442 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.442 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.441 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.441 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.441 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.441 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.441 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.441 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.441 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4f3x | NAD | Putative aldehyde dehydrogenase | / | 0.441 | |
| 4iae | 1DX | Alr2278 protein | / | 0.441 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.440 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2y4g | TIR | TamL | / | 0.440 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.440 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4b14 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.440 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.440 | |
| 5ag5 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.440 |