sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 1.000 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.651 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.633 | |
| 1rc0 | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.626 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.619 | |
| 1c3e | NHR | Phosphoribosylglycinamide formyltransferase | / | 0.559 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.556 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.513 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.508 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.505 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.502 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.492 | |
| 1rby | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.490 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.489 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.484 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.483 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.483 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.482 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.482 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.479 | |
| 4jk3 | NAD | Uncharacterized protein | / | 0.478 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.477 | |
| 4a4q | UX9 | Pol protein | / | 0.477 | |
| 4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.477 | |
| 2owk | SAH | Diphthine synthase | / | 0.476 | |
| 2p6k | SAH | Diphthine synthase | / | 0.475 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.475 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 2el3 | SAH | Diphthine synthase | / | 0.473 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.470 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.470 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.470 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.469 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.469 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.468 | |
| 1wng | SAH | Diphthine synthase | / | 0.468 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.468 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.467 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2p5c | SAH | Diphthine synthase | / | 0.466 | |
| 2p5f | SAH | Diphthine synthase | / | 0.466 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.466 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.466 | |
| 2e8r | SAH | Diphthine synthase | / | 0.465 | |
| 2eeq | SAH | Diphthine synthase | / | 0.465 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.465 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.465 | |
| 2dsi | SAH | Diphthine synthase | / | 0.464 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.463 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.463 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4mk0 | 29X | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.461 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.460 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2ehl | SAH | Diphthine synthase | / | 0.460 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.460 | |
| 2huq | SAH | Diphthine synthase | / | 0.460 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.460 | |
| 3vob | 9PC | Cell division protein FtsZ | / | 0.460 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.460 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 2f7z | 6EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2owu | SAH | Diphthine synthase | / | 0.459 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 4yfy | 1YJ | VioF | / | 0.459 | |
| 2ele | SAH | Diphthine synthase | / | 0.458 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.458 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 1ndi | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.457 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.457 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.457 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.457 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.457 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.457 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.457 | |
| 4kb9 | G79 | Protease | / | 0.457 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.456 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.456 | |
| 2uw5 | GVN | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.456 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.456 | |
| 2b60 | RIT | Pol polyprotein | / | 0.455 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.455 | |
| 2hut | SAH | Diphthine synthase | / | 0.455 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.455 | |
| 1vce | SAH | Diphthine synthase | / | 0.454 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 3dl9 | BCD | Vitamin D 25-hydroxylase | / | 0.454 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.453 | |
| 1nm1 | ATP | Major actin | / | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.453 | |
| 2dsg | SAH | Diphthine synthase | / | 0.453 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.453 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.453 | |
| 2qak | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2woe | AR6 | ADP-ribosyl-[dinitrogen reductase] glycohydrolase | 3.2.2.24 | 0.453 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.453 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.452 | |
| 2e4n | SAH | Diphthine synthase | / | 0.452 | |
| 2ejk | SAH | Diphthine synthase | / | 0.452 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2huv | SAH | Diphthine synthase | / | 0.452 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.452 | |
| 3nu5 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.452 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.452 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.452 | |
| 4uck | SAM | Large structural protein | / | 0.452 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.452 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.452 | |
| 1fej | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.451 | |
| 2fdd | 385 | Pol protein | / | 0.451 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 0.450 | |
| 1sny | NAP | LD36273p | / | 0.450 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.450 | |
| 2f3k | RO1 | Protease | / | 0.450 | |
| 2hs2 | 017 | Protease | / | 0.450 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.450 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.450 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.450 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.450 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.449 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.449 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.449 | |
| 3mx2 | TTP | Nucleoprotein | / | 0.449 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
| 4p53 | NAI | 2-epi-5-epi-valiolone synthase | / | 0.449 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.449 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.448 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 2c6o | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.448 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.448 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.448 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.448 | |
| 3zuy | TCH | Transporter | / | 0.448 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.448 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.448 | |
| 1aj8 | COA | Citrate synthase | / | 0.447 | |
| 1gqt | ACP | Ribokinase | / | 0.447 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.447 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1vij | BAY | Gag-Pol polyprotein | / | 0.447 | |
| 2egs | SAH | Diphthine synthase | / | 0.447 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.447 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.447 | |
| 3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.447 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.447 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.446 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.446 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3u9e | COA | Lmo1369 protein | / | 0.446 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.446 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.446 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 1ebw | BEI | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1w5y | BE6 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2e8s | SAH | Diphthine synthase | / | 0.445 | |
| 2el0 | SAH | Diphthine synthase | / | 0.445 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 2hux | SAH | Diphthine synthase | / | 0.445 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.445 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.445 | |
| 2p3b | 3TL | V-1 protease | / | 0.445 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.445 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.445 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.445 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.445 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 5ks7 | 2BA | Carnitine transport ATP-binding protein OpuCA | 3.6.3.32 | 0.445 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1sdv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.444 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.444 | |
| 2bqv | A1A | Protease | / | 0.444 | |
| 2e8h | SAH | Diphthine synthase | / | 0.444 | |
| 2q5k | AB1 | Protease | / | 0.444 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3gga | GGW | Gag-Pol polyprotein | / | 0.444 | |
| 3gob | HXX | DdmC | / | 0.444 | |
| 3pwm | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.444 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
| 1ec0 | BED | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.443 | |
| 2dxv | SAH | Diphthine synthase | / | 0.443 | |
| 2dxw | SAH | Diphthine synthase | / | 0.443 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.443 | |
| 2wkz | 5AH | Gag-Pol polyprotein | / | 0.443 | |
| 2y5k | YCU | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.443 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3rmw | UPG | Glycogenin-1 | 2.4.1.186 | 0.443 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.443 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.443 | |
| 1a8g | 2Z4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1ebz | BEC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.442 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.442 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
| 3r7v | Z02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4njt | 017 | Protease | / | 0.442 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2eld | SAH | Diphthine synthase | / | 0.441 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2idw | 017 | Protease | / | 0.441 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.441 | |
| 2owg | SAH | Diphthine synthase | / | 0.441 | |
| 2rkf | AB1 | Pol protein | / | 0.441 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3bxz | ADP | Protein translocase subunit SecA | / | 0.441 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.441 | |
| 3oxc | ROC | Protease | / | 0.441 | |
| 3sa3 | 23X | Protease | / | 0.441 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.441 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.441 | |
| 4e4n | 0NL | Tyrosine-protein kinase JAK1 | / | 0.441 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.441 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.441 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1dq9 | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.440 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.440 | |
| 1hsh | MK1 | Gag-Pol polyprotein | / | 0.440 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.440 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.440 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1rl8 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1scu | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.440 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 2e17 | SAH | Diphthine synthase | / | 0.440 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.440 | |
| 2jd0 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2z6r | SAH | Diphthine synthase | / | 0.440 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.440 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.440 | |
| 4qed | NAP | ElxO | / | 0.440 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |