sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1cgp | CMP | cAMP-activated global transcriptional regulator CRP |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 1.000 | |
| 1ruo | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.591 | |
| 3ryp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.584 | |
| 4hzf | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.584 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.579 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.555 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.553 | |
| 4i09 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.553 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.537 | |
| 2gzw | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.534 | |
| 4r8h | SP1 | cAMP-activated global transcriptional regulator CRP | / | 0.530 | |
| 1i5z | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.521 | |
| 1zrc | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.514 | |
| 4i01 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.513 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.507 | |
| 1g6n | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.502 | |
| 3qop | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.502 | |
| 4i0a | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.501 | |
| 3ryr | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.498 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.496 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.492 | |
| 3kcc | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.491 | |
| 4ft8 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.491 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.485 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.480 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.478 | |
| 3rou | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.478 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.477 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.477 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.474 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.474 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.474 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.474 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.471 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 4a4q | UX9 | Pol protein | / | 0.471 | |
| 3rpq | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.470 | |
| 3zuy | TCH | Transporter | / | 0.470 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.470 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.470 | |
| 1zrd | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.469 | |
| 2cdu | FAD | NADH oxidase | / | 0.468 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.467 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.466 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.466 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.466 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.466 | |
| 3lit | E15 | Protease | / | 0.466 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.466 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.464 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.464 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.464 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.463 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.462 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.462 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.462 | |
| 3d1z | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.460 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.460 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.460 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.460 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.459 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.459 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.459 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.459 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.459 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.458 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.458 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.458 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.458 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.458 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.458 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.457 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.455 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 3zux | TCH | Transporter | / | 0.455 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.455 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.455 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.454 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.454 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.454 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.454 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.454 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.454 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.454 | |
| 5a3b | APR | SIR2 family protein | / | 0.454 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.453 | |
| 1v9n | NDP | Malate dehydrogenase | 1.1.1.37 | 0.453 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 3nyg | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.453 | |
| 4kb9 | G79 | Protease | / | 0.453 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.452 | |
| 2emr | SAH | Diphthine synthase | / | 0.452 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.452 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 4ye3 | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.451 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.451 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.451 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.451 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.451 | |
| 3mws | 017 | Pol protein | / | 0.451 | |
| 4die | C5P | Cytidylate kinase | / | 0.451 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.451 | |
| 1c6y | MK1 | Protease | / | 0.450 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.450 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.450 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.450 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4c4o | NAD | SADH | / | 0.450 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.449 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.449 | |
| 2owk | SAH | Diphthine synthase | / | 0.449 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.449 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.448 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.448 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.448 | |
| 2p3c | 3TL | Protease | / | 0.448 | |
| 2pck | SAH | Diphthine synthase | / | 0.448 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.447 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.447 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.447 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.447 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 2i4u | DJR | Protease | / | 0.447 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.447 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.447 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.447 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.447 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.447 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.446 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1rl8 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.446 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.446 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3lin | E13 | Protease | / | 0.446 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.446 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.446 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.446 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.445 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.445 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.445 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.445 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.445 | |
| 2f3k | RO1 | Protease | / | 0.445 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.445 | |
| 2p3b | 3TL | V-1 protease | / | 0.445 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.445 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.445 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2pcm | SAH | Diphthine synthase | / | 0.444 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.444 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 3nu6 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3qih | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4o9k | CMK | Arabinose 5-phosphate isomerase | / | 0.444 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.444 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.443 | |
| 1hvj | A78 | Gag-Pol polyprotein | / | 0.443 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.443 | |
| 1osv | CHC | Bile acid receptor | / | 0.443 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.443 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.443 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.443 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.443 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.443 | |
| 3so9 | 017 | Pol protein | / | 0.443 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.443 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.443 | |
| 1c70 | L75 | Protease | / | 0.442 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.442 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.442 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.442 | |
| 2idw | 017 | Protease | / | 0.442 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.442 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.442 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4w6z | 8ID | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.442 | |
| 5kje | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.441 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2e07 | SAH | Diphthine synthase | / | 0.441 | |
| 2emu | SAH | Diphthine synthase | / | 0.441 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.441 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.441 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3cyw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3d1x | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3nbv | ANP | Ketohexokinase | / | 0.441 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.441 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.441 | |
| 3zps | EQM | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.441 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.441 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
| 4q1y | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.441 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5ijz | NAP | NADP-specific glutamate dehydrogenase | 1.4.1.4 | 0.441 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.440 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.440 | |
| 1okk | GCP | Signal recognition particle protein | / | 0.440 | |
| 1okk | GCP | Signal recognition particle receptor FtsY | / | 0.440 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.440 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.440 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3fx5 | KNI | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.440 | |
| 3liv | E16 | Protease | / | 0.440 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4njs | G08 | Protease | / | 0.440 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.440 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 |