sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nec | SAH | Putative SAM-dependent methyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 1.014 | |
| 2y1w | SFG | Histone-arginine methyltransferase CARM1 | / | 0.809 | |
| 3b3f | SAH | Histone-arginine methyltransferase CARM1 | / | 0.789 | |
| 5epe | SAH | Uncharacterized protein | / | 0.789 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.788 | |
| 2bzg | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.786 | |
| 5dxj | SFG | Histone-arginine methyltransferase CARM1 | / | 0.784 | |
| 3dmg | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.782 | |
| 3lcc | SAH | Thiocyanate methyltransferase 1 | / | 0.779 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.778 | |
| 5dwq | SFG | Histone-arginine methyltransferase CARM1 | / | 0.774 | |
| 2y1x | SAH | Histone-arginine methyltransferase CARM1 | / | 0.772 | |
| 3t7t | SAH | Uncharacterized protein | / | 0.770 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.767 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.766 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.766 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.766 | |
| 2qe6 | SAM | Uncharacterized protein | / | 0.765 | |
| 2yqz | SAM | Uncharacterized protein | / | 0.765 | |
| 3dlc | SAM | SAM (And some other nucleotide) binding motif:Generic methyltransferase | / | 0.763 | |
| 5jdz | SAH | Methyl transferase | / | 0.760 | |
| 5je3 | SAH | Methyl transferase | / | 0.760 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.756 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.754 | |
| 3grr | SAH | Probable ribosomal RNA small subunit methyltransferase A | / | 0.754 | |
| 3e8s | SAH | Uncharacterized protein | / | 0.752 | |
| 2zul | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.751 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.751 | |
| 4iv0 | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.749 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.746 | |
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.745 | |
| 2yx1 | SFG | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 2.1.1.228 | 0.744 | |
| 3gwz | SAH | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.744 | |
| 4x3q | SAH | SibL | / | 0.744 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.744 | |
| 5jr3 | SAH | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.744 | |
| 2hv9 | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.743 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.743 | |
| 3v97 | SAH | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.743 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.742 | |
| 1f3l | SAH | Protein arginine N-methyltransferase 3 | / | 0.741 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.740 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.739 | |
| 4fr0 | SAM | Arsenic methyltransferase | / | 0.739 | |
| 4yuz | S4M | Spermidine synthase, putative | / | 0.739 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.738 | |
| 3bgv | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.738 | |
| 4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.738 | |
| 5ccb | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.738 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.737 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.737 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.736 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.734 | |
| 5ccx | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.732 | |
| 1y8q | ATP | SUMO-activating enzyme subunit 2 | 6.3.2 | 0.731 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.729 | |
| 1yf3 | SAH | DNA adenine methylase | / | 0.729 | |
| 5je4 | SAH | Methyl transferase | / | 0.729 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.728 | |
| 1y9d | FAD | Pyruvate oxidase | 1.2.3.3 | 0.728 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.728 | |
| 5fa5 | MTA | Protein arginine N-methyltransferase 5 | / | 0.728 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.727 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.727 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.726 | |
| 4hh4 | SAH | CcbJ | / | 0.724 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.724 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.723 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.723 | |
| 2zzm | SAM | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 2.1.1.228 | 0.723 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.722 | |
| 3lst | SAH | CalO1 | / | 0.722 | |
| 4fzv | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.722 | |
| 5icf | SAH | (S)-norcoclaurine 6-O-methyltransferase | / | 0.722 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.720 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.720 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.720 | |
| 3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.719 | |
| 5bxy | SAH | Putative RNA methylase family UPF0020 | / | 0.719 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.718 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.718 | |
| 3iei | SAH | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.718 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.718 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.717 | |
| 3p9k | SAH | Caffeic acid O-methyltransferase | / | 0.717 | |
| 4qpp | SAH | Protein arginine N-methyltransferase 6 | / | 0.717 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.716 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.715 | |
| 4o29 | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.715 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.714 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.714 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.714 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.713 | |
| 4dcm | SAM | Ribosomal RNA large subunit methyltransferase G | 2.1.1.174 | 0.713 | |
| 4gek | GEK | Carboxy-S-adenosyl-L-methionine synthase | / | 0.713 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.711 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.711 | |
| 2xvm | SAH | Tellurite methyltransferase | 2.1.1.265 | 0.709 | |
| 3cbg | SAH | O-methyltransferase | / | 0.709 | |
| 3tos | SAH | CalS11 | / | 0.709 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.709 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.708 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.708 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.708 | |
| 5dx1 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.708 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.707 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.707 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.706 | |
| 3gxo | SAH | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.706 | |
| 3vc1 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.706 | |
| 4e2x | SAH | Methyltransferase | / | 0.706 | |
| 4xcx | SAH | Small RNA 2'-O-methyltransferase | / | 0.706 | |
| 1txz | APR | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.705 | |
| 2zth | SAM | Catechol O-methyltransferase | 2.1.1.6 | 0.705 | |
| 4c03 | SFG | Protein arginine N-methyltransferase 6 | / | 0.705 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.704 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.704 | |
| 4gqb | 0XU | Protein arginine N-methyltransferase 5 | / | 0.704 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.704 | |
| 4qdk | SAH | Magnesium-protoporphyrin O-methyltransferase | 2.1.1.11 | 0.703 | |
| 3grv | ADN | Probable ribosomal RNA small subunit methyltransferase A | / | 0.702 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.701 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.701 | |
| 2np7 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.701 | |
| 5e9w | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.701 | |
| 2v74 | SAH | Histone-arginine methyltransferase CARM1 | / | 0.700 | |
| 3wv8 | ATP | Hmd co-occurring protein HcgE | / | 0.700 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.699 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.699 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.699 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.699 | |
| 1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.698 | |
| 3epp | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.698 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.698 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.698 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.698 | |
| 2o07 | MTA | Spermidine synthase | 2.5.1.16 | 0.697 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.697 | |
| 3reo | SAH | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.696 | |
| 4dmg | SAM | Uncharacterized protein | / | 0.696 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.696 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.696 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.695 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.694 | |
| 4fgz | SAH | Phosphoethanolamine N-methyltransferase | / | 0.694 | |
| 1i9g | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.693 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.693 | |
| 4rtk | SAH | DNA adenine methylase | 2.1.1.72 | 0.693 | |
| 1rjd | SAM | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.692 | |
| 2g1p | SAH | DNA adenine methylase | 2.1.1.72 | 0.692 | |
| 3kpj | SAH | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.692 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.691 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.691 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.691 | |
| 3hvk | 719 | Catechol O-methyltransferase | 2.1.1.6 | 0.691 | |
| 3vc2 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.691 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.690 | |
| 3gry | SAM | Probable ribosomal RNA small subunit methyltransferase A | / | 0.690 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.689 | |
| 3lcu | SAH | 16S rRNA (guanine(1405)-N(7))-methyltransferase | 2.1.1.179 | 0.689 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.689 | |
| 5dx8 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.689 | |
| 1eg2 | MTA | Modification methylase RsrI | 2.1.1.72 | 0.688 | |
| 1fjx | SAH | Modification methylase HhaI | 2.1.1.37 | 0.688 | |
| 3duw | SAH | O-methyltransferase, putative | / | 0.688 | |
| 4a6d | SAM | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.688 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.687 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.687 | |
| 2h39 | ADQ | ADP-glucose phosphorylase | / | 0.687 | |
| 2zfu | SAH | Ribosomal RNA-processing protein 8 | / | 0.687 | |
| 2ih5 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.686 | |
| 4iwn | GEK | Carboxy-S-adenosyl-L-methionine synthase | / | 0.686 | |
| 4rtj | SFG | DNA adenine methylase | 2.1.1.72 | 0.686 | |
| 4yuv | S4M | Spermidine synthase, putative | / | 0.686 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.685 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.685 | |
| 3g8a | SAH | Ribosomal RNA small subunit methyltransferase G | / | 0.685 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.684 | |
| 3fpf | MTA | Uncharacterized protein | / | 0.684 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.684 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.683 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.682 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.682 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.681 | |
| 4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.681 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.680 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.680 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.680 | |
| 3qvw | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.680 | |
| 5e72 | SAM | N2, N2-dimethylguanosine tRNA methyltransferase | / | 0.680 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.679 | |
| 4gf5 | SAH | CalS11 | / | 0.679 | |
| 4mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.679 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.679 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.679 | |
| 1rje | SAH | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.678 | |
| 3o7w | SAM | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.678 | |
| 4dkj | SAH | Cytosine-specific methyltransferase | / | 0.678 | |
| 4yv1 | S4M | Spermidine synthase, putative | / | 0.678 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.677 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.676 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.676 | |
| 4d79 | ATP | tRNA threonylcarbamoyladenosine dehydratase | 6.1 | 0.676 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.675 | |
| 1qao | SAM | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.675 | |
| 3q87 | SAM | N6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY) | / | 0.675 | |
| 3sr4 | TT8 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.675 | |
| 5dxa | SFG | Histone-arginine methyltransferase CARM1 | / | 0.675 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.674 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.674 | |
| 1jr4 | CL4 | Catechol O-methyltransferase | 2.1.1.6 | 0.673 | |
| 1qaq | SFG | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.673 | |
| 5je2 | SAH | Methyl transferase | / | 0.673 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.672 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.672 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.671 | |
| 3c3y | SAH | O-methyltransferase | / | 0.671 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.670 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.670 | |
| 2bh2 | SAH | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | / | 0.670 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.670 | |
| 1uay | ADN | Oxidoreductase | / | 0.669 | |
| 2eju | SAH | tRNA (guanine(26)-N(2))-dimethyltransferase | / | 0.669 | |
| 2ytz | SAH | tRNA (guanine(26)-N(2))-dimethyltransferase | / | 0.669 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.669 | |
| 3kkj | FAD | Renalase | / | 0.669 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.668 | |
| 3rw9 | DSH | Spermidine synthase | 2.5.1.16 | 0.668 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.668 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.668 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.667 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.667 | |
| 5k7w | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.667 | |
| 1la2 | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.666 | |
| 3g07 | SAM | 7SK snRNA methylphosphate capping enzyme | 2.1.1 | 0.666 | |
| 3wdm | ADN | 4-phosphopantoate--beta-alanine ligase | 6.3.2.36 | 0.666 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.665 | |
| 3uq9 | TBN | Putative adenosine kinase | / | 0.665 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.664 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.664 | |
| 4c05 | SAH | Protein arginine N-methyltransferase 6 | / | 0.664 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.664 | |
| 4rtl | SFG | DNA adenine methylase | 2.1.1.72 | 0.664 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.663 | |
| 3p9c | SAH | Caffeic acid O-methyltransferase | / | 0.663 | |
| 1aqi | SAH | Modification methylase TaqI | 2.1.1.72 | 0.662 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.662 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.662 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.662 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.662 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.661 | |
| 3e9y | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.661 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.661 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.661 | |
| 1bc5 | SAH | Chemotaxis protein methyltransferase | 2.1.1.80 | 0.660 | |
| 1ty8 | ADP | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.660 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.660 | |
| 3iv6 | SAM | Uncharacterized protein | / | 0.660 | |
| 3lcv | SAM | 16S rRNA (guanine(1405)-N(7))-methyltransferase | 2.1.1.179 | 0.660 | |
| 4u7t | SAH | DNA (cytosine-5)-methyltransferase 3A | 2.1.1.37 | 0.660 | |
| 2h00 | SAH | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | / | 0.659 | |
| 3clt | FAD | Electron transfer flavoprotein subunit alpha | / | 0.659 | |
| 3n1s | 5GP | Purine nucleoside phosphoramidase | / | 0.659 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.659 | |
| 4kvz | SAH | PtnL protein | / | 0.659 | |
| 2v92 | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.658 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.658 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.658 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.658 | |
| 4htf | SAM | tRNA 5-carboxymethoxyuridine methyltransferase | / | 0.658 | |
| 1qan | SAH | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.657 | |
| 1hzz | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.656 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.656 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.656 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.656 | |
| 2cdu | ADP | NADH oxidase | / | 0.655 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.655 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.655 | |
| 4rto | SFG | DNA adenine methylase | 2.1.1.72 | 0.655 | |
| 1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.654 | |
| 1v59 | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.654 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.654 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.654 | |
| 3lhd | SAH | tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.219 | 0.653 | |
| 4qnu | GEK | tRNA U34 carboxymethyltransferase | / | 0.653 | |
| 2hms | NAI | Ktr system potassium uptake protein A | / | 0.652 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.652 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.652 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.652 | |
| 4mb2 | ATP | Uncharacterized protein | / | 0.652 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.651 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.651 | |
| 3lby | SAH | Uncharacterized protein | / | 0.651 | |
| 1nv8 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.650 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.650 | |
| 2pwy | SAH | tRNA (adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.220 | 0.650 | |
| 4ckb | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.650 | |
| 4r6x | SAH | Phosphoethanolamine N-methyltransferase | / | 0.650 |