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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lz5LDTAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lz5LDTAldose reductase1.1.1.211.000
3m64393Aldose reductase1.1.1.210.728
2pdxZSTAldose reductase1.1.1.210.727
3m4h388Aldose reductase1.1.1.210.725
2fz9ZSTAldose reductase1.1.1.210.705
4yu153NAldose reductase1.1.1.210.699
3lboLDTAldose reductase1.1.1.210.697
2hvoZSTAldose reductase1.1.1.210.687
3lqlLDTAldose reductase1.1.1.210.687
1z8962PAldose reductase1.1.1.210.677
2pf8NDPAldose reductase1.1.1.210.675
1us0LDTAldose reductase1.1.1.210.666
1t40ID5Aldose reductase1.1.1.210.662
2ikj393Aldose reductase1.1.1.210.654
2dv0ZSTAldose reductase1.1.1.210.653
3mc5393Aldose reductase1.1.1.210.648
1t41ID5Aldose reductase1.1.1.210.642
3ghuLDTAldose reductase1.1.1.210.641
4gca2X9Aldose reductase1.1.1.210.638
2hv5ZSTAldose reductase1.1.1.210.635
3m0iZSTAldose reductase1.1.1.210.632
3ghsLDTAldose reductase1.1.1.210.625
2pdfZSTAldose reductase1.1.1.210.623
2pdmZSTAldose reductase1.1.1.210.622
3mb9ZSTAldose reductase1.1.1.210.620
2pdu393Aldose reductase1.1.1.210.619
3lenZSTAldose reductase1.1.1.210.619
2iki388Aldose reductase1.1.1.210.618
2pdg47DAldose reductase1.1.1.210.616
2pdp393Aldose reductase1.1.1.210.615
3ld5LDTAldose reductase1.1.1.210.612
3t423T4Aldose reductase1.1.1.210.612
2pdbZSTAldose reductase1.1.1.210.609
3g5eQ74Aldose reductase1.1.1.210.609
1ieiZESAldose reductase1.1.1.210.608
2pdn47DAldose reductase1.1.1.210.604
2pzn393Aldose reductase1.1.1.210.604
2qxwLDTAldose reductase1.1.1.210.604
2pdq47DAldose reductase1.1.1.210.603
2fzdTOLAldose reductase1.1.1.210.601
2ikhLITAldose reductase1.1.1.210.598
2pd5ZSTAldose reductase1.1.1.210.598
3ghrLDTAldose reductase1.1.1.210.597
2fz8ZSTAldose reductase1.1.1.210.596
3ghtLDTAldose reductase1.1.1.210.596
1pwlBFIAldose reductase1.1.1.210.595
2pdh47DAldose reductase1.1.1.210.591
1el3I84Aldose reductase1.1.1.210.587
1frbZSTAldose reductase-related protein 2/0.580
2pdc393Aldose reductase1.1.1.210.579
2agtFIDAldose reductase1.1.1.210.566
2i17LDTAldose reductase1.1.1.210.565
2pdj393Aldose reductase1.1.1.210.560
2duxZSTAldose reductase1.1.1.210.554
1z3n3NAAldose reductase1.1.1.210.548
2pd9FIDAldose reductase1.1.1.210.545
2duzZSTAldose reductase1.1.1.210.540
2f2kTGGAldose reductase1.1.1.210.528
1ah3TOLAldose reductase1.1.1.210.525
2i16LDTAldose reductase1.1.1.210.514
2pdlTOLAldose reductase1.1.1.210.514
2fzbTOLAldose reductase1.1.1.210.512
1ekoI84Aldose reductase1.1.1.210.508
3v35NTIAldose reductase1.1.1.210.499
2inzOHPAldose reductase1.1.1.210.498
2oazI96Methionine aminopeptidase 2/0.497
5liu388Aldo-keto reductase family 1 member B101.1.10.495
1lkeDOGBilin-binding protein/0.493
1yw8A75Methionine aminopeptidase 2/0.493
2iqdLPAAldose reductase1.1.1.210.492
4ga8SBIAldo-keto reductase family 1 member B101.1.10.491
2ga2A19Methionine aminopeptidase 2/0.488
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.487
4dbw511Aldo-keto reductase family 1 member C3/0.486
4wevSUZAldo-keto reductase family 1 member B101.1.10.486
4u163C0Muscarinic acetylcholine receptor M3/0.486
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.484
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.484
2wmdZZ0NmrA-like family domain-containing protein 1/0.481
3gfbNADL-threonine 3-dehydrogenase/0.481
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
1w6jR71Lanosterol synthase5.4.99.70.478
1yw9A84Methionine aminopeptidase 2/0.478
1lnmDTXBilin-binding protein/0.476
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.476
1zq5E04Aldo-keto reductase family 1 member C3/0.475
4bftZVTPantothenate kinase2.7.1.330.475
1s7gNADNAD-dependent protein deacylase 2/0.474
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
4fam0SZAldo-keto reductase family 1 member C3/0.474
4xo7ASDAldo-keto reductase family 1 member C2/0.474
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.473
4jtrIZPAldo-keto reductase family 1 member C2/0.473
4k4eK4ETankyrase-12.4.2.300.473
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.473
1t7o152Carnitine O-acetyltransferase2.3.1.70.472
2ea4F79Methionine aminopeptidase 2/0.472
2xupTZ5Acetylcholinesterase3.1.1.70.472
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.472
4psbGA3Cytokinin-specific binding protein/0.472
1yw7A41Methionine aminopeptidase 2/0.471
2nvcITAAldose reductase1.1.1.210.471
3af4GCPPantothenate kinase2.7.1.330.471
3pn1IVHDNA ligase/0.471
4stdBFSScytalone dehydratase4.2.1.940.471
1dgbNDPCatalase1.11.1.60.470
1r5hAO2Methionine aminopeptidase 2/0.470
2pdyFIDAldose reductase1.1.1.210.470
2xuhTZ4Acetylcholinesterase3.1.1.70.470
3uweVJJAldo-keto reductase family 1 member C3/0.470
4h7c10HAldo-keto reductase family 1 member C3/0.470
4jtrIBPAldo-keto reductase family 1 member C2/0.470
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.469
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.468
4bfwZVWPantothenate kinase2.7.1.330.468
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.468
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466
1q83TZ5Acetylcholinesterase3.1.1.70.466
1r58AO5Methionine aminopeptidase 2/0.466
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.466
2xufTZ4Acetylcholinesterase3.1.1.70.466
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.466
4jq2SUZAldo-keto reductase family 1 member C2/0.466
4kn2LYAFolate receptor beta/0.466
1gky5GPGuanylate kinase2.7.4.80.465
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
4hmn16JAldo-keto reductase family 1 member C3/0.465
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1w4lGL8Acetylcholinesterase3.1.1.70.464
3af1GDPPantothenate kinase2.7.1.330.464
1esmCOAPantothenate kinase2.7.1.330.463
2cbqTH2Neocarzinostatin/0.463
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.463
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2xegCI9Glutamate carboxypeptidase 23.4.17.210.463
4dbs0HVAldo-keto reductase family 1 member C3/0.463
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.463
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.462
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.462
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.462
1x2eATXProline iminopeptidase3.4.11.50.462
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
3ntqNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.462
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.462
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.462
4j7gTRHPCZA361.3/0.462
4phlPILPhosphodiesterase/0.462
1ogjFADFerredoxin--NADP reductase1.18.1.20.461
2f3815MAldo-keto reductase family 1 member C3/0.461
2zs9ADPPantothenate kinase2.7.1.330.461
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
4i5xFLFAldo-keto reductase family 1 member B101.1.10.461
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.461
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1rxjBNIStreptavidin/0.460
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.460
2xuiTZ5Acetylcholinesterase3.1.1.70.460
3b82NADExotoxin A2.4.2.360.460
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.460
3h3r14HCollagen type IV alpha-3-binding protein/0.460
3h7rNAPAldo-keto reductase family 4 member C8/0.460
4bjbP34Tankyrase-22.4.2.300.460
1hfqMOTDihydrofolate reductase1.5.1.30.459
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.459
1odnAPVIsopenicillin N synthase1.21.3.10.459
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1zgcA2EAcetylcholinesterase3.1.1.70.459
2pdwFIDAldose reductase1.1.1.210.459
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.459
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.459
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.458
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
1zgbA1EAcetylcholinesterase3.1.1.70.458
2zsbADPPantothenate kinase2.7.1.330.458
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.458
1ry0PG2Aldo-keto reductase family 1 member C3/0.457
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.457
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.457
3p9tTCLRepressor/0.457
4kn104JFolate receptor beta/0.457
4lrhFOLFolate receptor alpha/0.457
5d5aCAUBeta-2 adrenergic receptor/0.457
1gjrFADFerredoxin--NADP reductase1.18.1.20.456
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.456
1ry8RUTAldo-keto reductase family 1 member C3/0.456
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.456
3ojxFMNNADPH--cytochrome P450 reductase/0.456
3ugrIMNAldo-keto reductase family 1 member C3/0.456
3zc3FADFerredoxin--NADP reductase1.18.1.20.456
4bfxZVXPantothenate kinase2.7.1.330.456
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.455
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2wzySQXSoluble acetylcholine receptor/0.455
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.455
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.455
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.455
1zuaTOLAldo-keto reductase family 1 member B101.1.10.454
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.454
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
3zv7NHGAcetylcholinesterase3.1.1.70.454
4kniE1ECarbonic anhydrase 24.2.1.10.454
1ihiIU5Aldo-keto reductase family 1 member C2/0.453
1pqc444Oxysterols receptor LXR-beta/0.453
2aot2PMHistamine N-methyltransferase2.1.1.80.453
2aotSAHHistamine N-methyltransferase2.1.1.80.453
2ipw2CLAldose reductase1.1.1.210.453
2w6cBM4Acetylcholinesterase3.1.1.70.453
3q9bB3NAcetylpolyamine amidohydrolase/0.453
3r8hZOMAldo-keto reductase family 1 member C3/0.453
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.453
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.452
1dghNDPCatalase1.11.1.60.452
1odcA8BAcetylcholinesterase3.1.1.70.452
2aovC2MHistamine N-methyltransferase2.1.1.80.452
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
4e0u0MVCyclic dipeptide N-prenyltransferase/0.452
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.452
4jtqFLPAldo-keto reductase family 1 member C2/0.452
1dp2LPBThiosulfate sulfurtransferase/0.451
1s07PLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.451
2cekN8TAcetylcholinesterase3.1.1.70.451
2jf6S55Strictosidine-O-beta-D-glucosidase3.2.1.1050.451
2w3mFOLDihydrofolate reductase1.5.1.30.451
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.451
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.451
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.451
1h42FADFerredoxin--NADP reductase1.18.1.20.450
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.450
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.450
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1tiqCOASpermidine/spermine N(1)-acetyltransferase/0.450
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
2rqfJH3Hemolymph juvenile hormone binding protein/0.450
2vt4P32Beta-1 adrenergic receptor/0.450
3ghvGHCDihydrofolate reductase1.5.1.30.450
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.450
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.449
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.449
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.449
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2zevIPEGeranylgeranyl pyrophosphate synthase/0.449
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3vjkM51Dipeptidyl peptidase 4/0.449
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.449
4ea2RWZDehydrosqualene synthase/0.449
4fhd0TTSpore photoproduct lyase/0.449
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.449
5stdUNNScytalone dehydratase4.2.1.940.449
5cxv0HKMuscarinic acetylcholine receptor M1/0.449
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.448
1xf0ASDAldo-keto reductase family 1 member C3/0.448
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.448
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.448
2vqqTFGHistone deacetylase 43.5.1.980.448
3af2ACPPantothenate kinase2.7.1.330.448
3c3xNAPEugenol synthase 11.1.1.3180.448
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3r6iJMSAldo-keto reductase family 1 member C3/0.448
3vo2FADFerredoxin--NADP reductase/0.448
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.448
3zkuHCVIsopenicillin N synthase1.21.3.10.448
4b67NAPL-ornithine N(5)-monooxygenase/0.448
4yfy0FXVioF/0.448
1a4lDCFAdenosine deaminase3.5.4.40.447
1enpNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.447
1fmjRTLRetinol dehydratase/0.447
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.447
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.447
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2aclL05Oxysterols receptor LXR-alpha/0.447
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.447
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
3af0GDPPantothenate kinase2.7.1.330.447
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.447
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.447
3p0pNNFTankyrase-22.4.2.300.447
4a1oAMZBifunctional purine biosynthesis protein PurH2.1.2.30.447
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4kn0MTXFolate receptor beta/0.447
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.447
5fd8A5APutative carboxypeptidase yocD/0.447
1d3dBZTProthrombin3.4.21.50.446
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.446
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3ccbB2YDipeptidyl peptidase 4/0.446
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.446
3lxeTORCarbonic anhydrase 14.2.1.10.446
3v0p4GWHisto-blood group ABO system transferase/0.446
4dz5NAPAldo-keto reductase family 1 member C3/0.446
4kdrSAHUbiquinone biosynthesis O-methyltransferase/0.446
4m0cFMNFMN-dependent NADH-azoreductase 1/0.446
4odoFK5Peptidyl-prolyl cis-trans isomerase/0.446
4paaTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.446
1vp5NAPOxidoreductase, aldo/keto reductase family/0.445
2ea2F77Methionine aminopeptidase 2/0.445
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.445
2hxzH7JCathepsin S3.4.22.270.445
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.445
2r6jNDPEugenol synthase 11.1.1.3180.445
3c1oNAPEugenol synthase/0.445
3nwlNDPCatalase1.11.1.60.445
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3t0kDCQSulfide-quinone reductase/0.445
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.445
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4araC56Acetylcholinesterase3.1.1.70.445
4fa30SLAldo-keto reductase family 1 member C3/0.445
4hyf1AKTankyrase-22.4.2.300.445
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.444
1dlrMXADihydrofolate reductase1.5.1.30.444
1e2lTMCThymidine kinase/0.444
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.444
2e0nSAHPrecorrin-2 C20-methyltransferase/0.444
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.444
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.444
3e4vFMNUncharacterized protein/0.444
3iu9T07Methionine aminopeptidase 2/0.444
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4l1xNAPAldo-keto reductase family 1 member C2/0.444
4li61XOTankyrase-12.4.2.300.444
4relKMPGlycosyltransferase/0.444
5jqhCAUBeta-2 adrenergic receptor/0.444
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.443
1az2NAPAldose reductase1.1.1.210.443
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
1qzyTDEMethionine aminopeptidase 2/0.443
1vkgCRIHistone deacetylase 83.5.1.980.443
1wm1PTBProline iminopeptidase3.4.11.50.443
2ohjFMNType A flavoprotein FprA10.443
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.443
3c3dFO12-phospho-L-lactate transferase/0.443
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.443
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3rthRTHBeta-secretase 13.4.23.460.443
4ey6GNTAcetylcholinesterase3.1.1.70.443
4jqaID8Aldo-keto reductase family 1 member C2/0.443
5cc9DDFDihydrofolate reductase1.5.1.30.443
1queFADFerredoxin--NADP reductase1.18.1.20.442
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2geuCOKPantothenate kinase2.7.1.330.442
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.442
2pb1NFGGlucan 1,3-beta-glucosidase/0.442
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3zovWZVBeta-secretase 13.4.23.460.442
4bfvZVVPantothenate kinase2.7.1.330.442
4kebFOLDihydrofolate reductase1.5.1.30.442
4mrxCZHObelin/0.442
1e66HUXAcetylcholinesterase3.1.1.70.441
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1u65CP0Acetylcholinesterase3.1.1.70.441
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
2j3qTFLAcetylcholinesterase3.1.1.70.441
2qryTPSThiamine-binding periplasmic protein/0.441
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.441
2uuk897Prothrombin3.4.21.50.441
2xefAR8Glutamate carboxypeptidase 23.4.17.210.441
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.20.441
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3elePLPAminotransferase/0.441
3f3y4OABile salt sulfotransferase2.8.2.140.441
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.441
5dsg0HKMuscarinic acetylcholine receptor M4/0.441
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.440
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2d06ESTSulfotransferase 1A12.8.2.10.440
2stdCRPScytalone dehydratase4.2.1.940.440
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2wm3NFLNmrA-like family domain-containing protein 1/0.440
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.440
3g5iDNBPyrimidine-specific ribonucleoside hydrolase RihA/0.440
3mauPLRPutative sphingosine-1-phosphate lyase/0.440
3n39FMNProtein NrdI/0.440
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440