Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3fmo | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3fmo | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 1.000 | |
2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.514 | |
1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
1t57 | FMN | Conserved protein | / | 0.497 | |
4o0m | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.496 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.491 | |
3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.489 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.488 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.485 | |
1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.483 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.482 | |
3up0 | D7S | aceDAF-12 | / | 0.481 | |
1db1 | VDX | Vitamin D3 receptor | / | 0.480 | |
2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.480 | |
5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.480 | |
1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.478 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.477 | |
4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.477 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.474 | |
2hb8 | MVD | Vitamin D3 receptor | / | 0.474 | |
2zyn | BCD | Periplasmic binding protein | / | 0.474 | |
3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.474 | |
1txi | TX5 | Vitamin D3 receptor | / | 0.473 | |
2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.473 | |
2hb7 | O1C | Vitamin D3 receptor | / | 0.473 | |
4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.473 | |
3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.472 | |
3zhb | NAP | Putative dehydrogenase | / | 0.472 | |
4cf7 | ADP | Adenylate kinase | / | 0.472 | |
1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
1sze | 173 | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.471 | |
1tf7 | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.471 | |
1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.471 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
3vt4 | 5YI | Vitamin D3 receptor | / | 0.471 | |
4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.471 | |
1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.470 | |
2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.470 | |
4j49 | 1J1 | Uncharacterized protein | / | 0.470 | |
4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.469 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.469 | |
2ham | C33 | Vitamin D3 receptor | / | 0.469 | |
1ie8 | KH1 | Vitamin D3 receptor | / | 0.468 | |
1ie9 | VDX | Vitamin D3 receptor | / | 0.468 | |
2has | C3O | Vitamin D3 receptor | / | 0.468 | |
3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.467 | |
1u9i | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.467 | |
3bgx | MEF | Thymidylate synthase | / | 0.467 | |
4ruj | VDX | Vitamin D3 receptor A | / | 0.467 | |
4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.467 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
3vrw | YS5 | Vitamin D3 receptor | / | 0.466 | |
4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
5c4c | UPG | Histo-blood group ABO system transferase | / | 0.466 | |
1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
1rkh | VD2 | Vitamin D3 receptor | / | 0.465 | |
2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.465 | |
2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.465 | |
2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.465 | |
3w0c | 6DS | Vitamin D3 receptor | / | 0.465 | |
4fhi | 0S4 | Vitamin D3 receptor A | / | 0.465 | |
1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.464 | |
2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.464 | |
2z50 | 028 | Geranylgeranyl pyrophosphate synthase | / | 0.464 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.464 | |
1rk3 | VDX | Vitamin D3 receptor | / | 0.463 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.463 | |
2gc8 | 885 | Polyprotein | / | 0.463 | |
2o4j | VD4 | Vitamin D3 receptor | / | 0.463 | |
2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.463 | |
4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.463 | |
2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.462 | |
3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.462 | |
3dvl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.462 | |
3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.462 | |
4g20 | 484 | Vitamin D3 receptor A | / | 0.462 | |
5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.462 | |
7cat | NDP | Catalase | 1.11.1.6 | 0.462 | |
1ny5 | ADP | Transcriptional regulator (NtrC family) | / | 0.461 | |
1v59 | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.461 | |
2har | OCC | Vitamin D3 receptor | / | 0.461 | |
2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
2x8h | FAD | Thioredoxin glutathione reductase | / | 0.460 | |
3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.460 | |
3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.460 | |
3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.460 | |
4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.460 | |
1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.459 | |
3up3 | XCA | aceDAF-12 | / | 0.459 | |
3w0i | O11 | Vitamin D3 receptor | / | 0.459 | |
3w5r | LOA | Vitamin D3 receptor | / | 0.459 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.459 | |
4g1y | 0VO | Vitamin D3 receptor A | / | 0.459 | |
1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
1hk4 | T44 | Serum albumin | / | 0.457 | |
1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.457 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.456 | |
1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.456 | |
1zdw | FLV | Prenyltransferase | / | 0.456 | |
2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
3zux | TCH | Transporter | / | 0.456 | |
4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.456 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.455 | |
2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.455 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
2zl9 | VDA | Vitamin D3 receptor | / | 0.455 | |
3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.455 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
4g1d | 0VK | Vitamin D3 receptor A | / | 0.455 | |
4q03 | GDP | GTPase KRas | / | 0.455 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.455 | |
8cat | NDP | Catalase | 1.11.1.6 | 0.455 | |
5jtb | ZMA | Adenosine receptor A2a | / | 0.455 | |
1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.454 | |
1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.454 | |
2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
2vpr | TDC | Tetracycline repressor protein class H | / | 0.454 | |
3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
4rel | KMP | Glycosyltransferase | / | 0.454 | |
1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.453 | |
2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
2o4r | VD5 | Vitamin D3 receptor | / | 0.453 | |
2rtr | IMI | Streptavidin | / | 0.453 | |
2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.453 | |
3a78 | 3EV | Vitamin D3 receptor | / | 0.453 | |
3bgx | TMP | Thymidylate synthase | / | 0.453 | |
3w0j | T08 | Vitamin D3 receptor | / | 0.453 | |
3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
4glx | 0XS | DNA ligase | 6.5.1.2 | 0.453 | |
4itf | TFY | Vitamin D3 receptor | / | 0.453 | |
1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
2c2a | ADP | Sensor histidine kinase | / | 0.452 | |
2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.452 | |
2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.452 | |
3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
4at0 | FAD | Possible succinate dehydrogenase | / | 0.452 | |
4dem | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.452 | |
4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
2tps | TPS | Thiamine-phosphate synthase | / | 0.451 | |
2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.451 | |
4fqs | LYA | Thymidylate synthase ThyA | / | 0.451 | |
4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.451 | |
4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.451 | |
1cul | FOK | Adenylate cyclase type 2 | / | 0.450 | |
1cul | FOK | Adenylate cyclase type 5 | / | 0.450 | |
1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
1f5f | DHT | Sex hormone-binding globulin | / | 0.450 | |
1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.450 | |
1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.450 | |
1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.450 | |
1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.450 | |
2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.450 | |
2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.450 | |
3zei | AWH | O-acetylserine sulfhydrylase | / | 0.450 | |
4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
5fuw | THM | Thymidine kinase, putative | / | 0.450 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.450 | |
1nec | FMN | Oxygen-insensitive NAD(P)H nitroreductase | 1 | 0.449 | |
2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
2bxq | IMN | Serum albumin | / | 0.449 | |
2zla | VDB | Vitamin D3 receptor | / | 0.449 | |
3e6y | CW1 | 14-3-3-like protein C | / | 0.449 | |
3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.449 | |
4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
4q0k | GA3 | Phytohormone-binding protein | / | 0.448 | |
5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.448 | |
5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.448 | |
1s19 | MC9 | Vitamin D3 receptor | / | 0.447 | |
2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.447 | |
2hcd | BIV | Vitamin D3 receptor A | / | 0.447 | |
2x6o | 2TC | Tetracycline repressor protein class D | / | 0.447 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.447 | |
3m3z | 3F5 | Heat shock cognate 71 kDa protein | / | 0.447 | |
3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.447 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
4q0a | 4OA | Vitamin D3 receptor A | / | 0.447 | |
1ga8 | UPF | LgtC | / | 0.446 | |
2fhl | BNI | Avidin-related protein 4/5 | / | 0.446 | |
2p5u | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
3cob | ADP | Kinesin heavy chain-like protein | / | 0.446 | |
3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.446 | |
3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.446 | |
3s1a | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.446 | |
3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
3vrv | YSD | Vitamin D3 receptor | / | 0.446 | |
3w0y | DS4 | Vitamin D3 receptor | / | 0.446 | |
4blr | UTP | NTPase P4 | / | 0.446 | |
4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.446 | |
4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.446 | |
4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.445 | |
1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.445 | |
2pda | TPP | Pyruvate synthase | / | 0.445 | |
2wsi | FAD | FAD synthase | 2.7.7.2 | 0.445 | |
3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.445 | |
3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.445 | |
4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.445 | |
4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.445 | |
4fx2 | FMN | Flavodoxin | / | 0.445 | |
4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.445 | |
4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
1yre | COA | Uncharacterized protein | / | 0.444 | |
2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.444 | |
3cgc | COA | Coenzyme A disulfide reductase | / | 0.444 | |
3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.444 | |
3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.444 | |
4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.444 | |
1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.443 | |
1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.443 | |
1s0z | EB1 | Vitamin D3 receptor | / | 0.443 | |
1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
2hc4 | VDX | Vitamin D3 receptor A | / | 0.443 | |
2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.443 | |
3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.443 | |
3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.443 | |
3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
3jzm | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.443 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
3w0h | W12 | Vitamin D3 receptor | / | 0.443 | |
4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.443 | |
1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.442 | |
1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
2j08 | IRF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
2p0r | LEU_LEU_ACE_AR7 | Calpain-9 | / | 0.442 | |
2quj | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.442 | |
2v1a | FMN | NPH1-1 | / | 0.442 | |
3gts | D3M | DdmC | / | 0.442 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
3kpz | ZNE | Vitamin D3 receptor | / | 0.442 | |
3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.442 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.442 | |
4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.442 | |
4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.442 | |
4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.442 | |
4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.442 | |
4y1b | NAP | AntE | / | 0.442 | |
4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.442 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
1lnm | DTX | Bilin-binding protein | / | 0.441 | |
1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.441 | |
1u3w | FXY | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.441 | |
1wc3 | APC | Adenylate cyclase | / | 0.441 | |
1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
4fhd | 0TT | Spore photoproduct lyase | / | 0.441 | |
4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.441 | |
4j7h | TRH | PCZA361.3 | / | 0.441 | |
4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.441 | |
1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
2v7q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
3vt6 | 5YI | Vitamin D3 receptor | / | 0.440 | |
4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.440 | |
4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.440 | |
4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.440 | |
4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.440 | |
5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.440 |