sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ndj | BTN | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1ndj | BTN | Streptavidin | / | 1.000 | |
| 1nc9 | IMI | Streptavidin | / | 0.633 | |
| 3wyp | BSO | Streptavidin | / | 0.609 | |
| 2zsc | BTN | Tamavidin2 | / | 0.600 | |
| 1swp | BTQ | Streptavidin | / | 0.599 | |
| 3ry2 | BTN | Streptavidin | / | 0.599 | |
| 1sre | HAB | Streptavidin | / | 0.591 | |
| 1n9m | BTN | Streptavidin | / | 0.590 | |
| 1mk5 | BTN | Streptavidin | / | 0.587 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.586 | |
| 1stp | BTN | Streptavidin | / | 0.585 | |
| 2izf | BTN | Streptavidin | / | 0.585 | |
| 4ggz | BTN | Bll1558 protein | / | 0.583 | |
| 1srg | MHB | Streptavidin | / | 0.576 | |
| 4yvb | BTN | Streptavidin | / | 0.574 | |
| 1sri | DMB | Streptavidin | / | 0.572 | |
| 1swd | BTN | Streptavidin | / | 0.570 | |
| 2rtg | BTN | Streptavidin | / | 0.568 | |
| 2rtf | BTN | Streptavidin | / | 0.567 | |
| 1lcw | SHM | Streptavidin | / | 0.564 | |
| 2izk | GLL | Streptavidin | / | 0.563 | |
| 4bx7 | B4F | Streptavidin | / | 0.562 | |
| 2izg | BTN | Streptavidin | / | 0.560 | |
| 2rtq | IMI | Streptavidin | / | 0.558 | |
| 2izh | BTN | Streptavidin | / | 0.557 | |
| 1df8 | BTN | Streptavidin | / | 0.554 | |
| 1srh | MOB | Streptavidin | / | 0.550 | |
| 4gd9 | BTN | Streptavidin | / | 0.550 | |
| 1avd | BTN | Avidin | / | 0.549 | |
| 1luq | BTN | Streptavidin | / | 0.547 | |
| 1swt | BTN | Streptavidin | / | 0.544 | |
| 2rtr | IMI | Streptavidin | / | 0.542 | |
| 2rti | GLL | Streptavidin | / | 0.540 | |
| 2y3f | BTN | Streptavidin | / | 0.540 | |
| 4dne | DTB | Streptavidin | / | 0.537 | |
| 2rtp | IMI | Streptavidin | / | 0.536 | |
| 2izl | IMI | Streptavidin | / | 0.535 | |
| 2rtd | BTN | Streptavidin | / | 0.532 | |
| 2rto | IMI | Streptavidin | / | 0.530 | |
| 2rte | BTN | Streptavidin | / | 0.528 | |
| 1swp | BTN | Streptavidin | / | 0.526 | |
| 2rtn | IMI | Streptavidin | / | 0.526 | |
| 2rtk | GLL | Streptavidin | / | 0.524 | |
| 1rxh | BNI | Streptavidin | / | 0.521 | |
| 1srf | MTB | Streptavidin | / | 0.521 | |
| 2rtm | IMI | Streptavidin | / | 0.521 | |
| 1srj | NAB | Streptavidin | / | 0.520 | |
| 3wzn | BTN | Streptavidin | / | 0.518 | |
| 3wyq | BTN | Streptavidin | / | 0.517 | |
| 4gda | BTN | Streptavidin | / | 0.517 | |
| 2jgs | BTN | Avidin | / | 0.515 | |
| 3vhh | VHH | Avidin | / | 0.515 | |
| 1i9h | BNI | Streptavidin | / | 0.514 | |
| 3vhm | NPK | Avidin | / | 0.514 | |
| 1swn | BTN | Streptavidin | / | 0.513 | |
| 1lcz | BH7 | Streptavidin | / | 0.512 | |
| 3vgw | NVZ | Avidin | / | 0.512 | |
| 2avi | BTN | Avidin | / | 0.510 | |
| 3vhi | VHI | Avidin | / | 0.510 | |
| 4z28 | BTN | Hoefavidin | / | 0.502 | |
| 3rdq | DTB | Streptavidin | / | 0.501 | |
| 2uz2 | BTN | Avd protein | / | 0.500 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.497 | |
| 2c4i | BTN | Avidin | / | 0.492 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.492 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.485 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.484 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.483 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.480 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.480 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.479 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.479 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.478 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.477 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.477 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.477 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.475 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.475 | |
| 4bue | JQF | Tankyrase-2 | 2.4.2.30 | 0.474 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.474 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.474 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 5dp2 | NAP | CurF | / | 0.471 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.470 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.470 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.470 | |
| 2izj | BTN | Streptavidin | / | 0.470 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2izi | BTN | Streptavidin | / | 0.469 | |
| 1lke | DOG | Bilin-binding protein | / | 0.468 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.468 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.468 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.468 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.468 | |
| 3klb | FMN | Uncharacterized protein | / | 0.467 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.466 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.466 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.466 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.465 | |
| 2uyw | BTN | Avd protein | / | 0.465 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.464 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.463 | |
| 4e32 | DWN | Methyltransferase | / | 0.463 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.463 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.462 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4buf | F36 | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 4iei | ADP | Gene 2 protein | / | 0.462 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.461 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.461 | |
| 1bx9 | GLY_GGL_FOE | Glutathione S-transferase F2 | 2.5.1.18 | 0.460 | |
| 1e2n | RCA | Thymidine kinase | / | 0.460 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.460 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.459 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.459 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2r8p | T6F | Transketolase 1 | / | 0.459 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.458 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.458 | |
| 4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.458 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.457 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.457 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.457 | |
| 4bus | 32F | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.455 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.455 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.455 | |
| 1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.454 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.454 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.454 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.454 | |
| 3ies | M24 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.454 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.454 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.454 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.453 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.453 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.453 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.452 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.452 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.452 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.452 | |
| 1ecb | 5GP | Amidophosphoribosyltransferase | / | 0.451 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.451 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.451 | |
| 2ejz | SAH | Diphthine synthase | / | 0.451 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.451 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.451 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.450 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3rim | TPP | Transketolase | 2.2.1.1 | 0.450 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.450 | |
| 4hkk | AGI | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.450 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.450 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.449 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.449 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.449 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.449 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
| 3ngq | 1PS | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.449 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.449 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.448 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.448 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.448 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.448 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3eks | CY9 | Actin-5C | / | 0.448 | |
| 3rno | NAP | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.448 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.448 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.448 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.448 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.448 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.448 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.447 | |
| 3ko5 | ADP | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.447 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4hlh | 20D | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.446 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.446 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.446 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 4e2z | JHZ | Methyltransferase | / | 0.446 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.446 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4phl | PIL | Phosphodiesterase | / | 0.446 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.446 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.446 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.446 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.445 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 2mm3 | CHO | Gastrotropin | / | 0.445 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.445 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.445 | |
| 3up0 | D7S | aceDAF-12 | / | 0.445 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.445 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.445 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.444 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.444 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.444 | |
| 2imk | GTX | AGAP009194-PA | / | 0.444 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.444 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.444 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.444 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.444 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4k4f | K4F | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 5aku | 29F | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.443 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.443 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.443 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.443 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.443 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.443 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.442 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.442 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.442 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.442 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.442 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.442 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.442 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.442 | |
| 4hl1 | ZZ7 | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 4rgs | V55 | Repressor protein | / | 0.442 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.441 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.441 | |
| 1ye6 | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.441 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2r8o | T5X | Transketolase 1 | / | 0.441 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.441 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.441 | |
| 3e6e | DCS | Alanine racemase | / | 0.441 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.441 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.441 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.441 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.440 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.440 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.440 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.440 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.440 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.440 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.440 |