sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5cvc | PLP | Serine racemase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5cvc | PLP | Serine racemase | / | 1.000 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.494 | |
| 3u9e | COA | Lmo1369 protein | / | 0.492 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.484 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.476 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.476 | |
| 2clo | PLS | Tryptophan synthase beta chain | 4.2.1.20 | 0.474 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.474 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.473 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.472 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.472 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.471 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.469 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.468 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.468 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.468 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.468 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.468 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.466 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.466 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.466 | |
| 2ejz | SAH | Diphthine synthase | / | 0.465 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.465 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.465 | |
| 2bue | COA | AAC(6')-Ib | / | 0.464 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.464 | |
| 1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.463 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.463 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.463 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.462 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.462 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.461 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3w2m | ZRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.461 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.461 | |
| 4lxm | 1YU | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.460 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.460 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 4k81 | GTP | GTPase HRas | / | 0.460 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.459 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.458 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.458 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.458 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.457 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.456 | |
| 1nge | ATP | Heat shock cognate 71 kDa protein | / | 0.456 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.456 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.456 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.456 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.455 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.455 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.455 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.455 | |
| 2r1r | TTP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.455 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.455 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.455 | |
| 3ieu | GDP | GTPase Era | / | 0.455 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.455 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 4cnz | ADP | Nitrogen regulatory protein P-II 1 | / | 0.455 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.455 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.454 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 4e07 | ACP | Plasmid partitioning protein ParF | / | 0.454 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.453 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.453 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.453 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.453 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.453 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.452 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.452 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.452 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.452 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.452 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 3gob | HXX | DdmC | / | 0.452 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.452 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.452 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.452 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 1hk1 | T44 | Serum albumin | / | 0.451 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.451 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.451 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.451 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.451 | |
| 1atr | ADP | Heat shock cognate 71 kDa protein | / | 0.450 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.450 | |
| 2rgx | AP5 | Adenylate kinase | / | 0.450 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.450 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.450 | |
| 4qvb | F42 | F420H(2)-dependent reductase Rv1155 | 1.4.3.5 | 0.450 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.449 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.449 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.449 | |
| 2vut | NAD | Nitrogen metabolite repression protein nmrA | / | 0.449 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.449 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.449 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.448 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.448 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.448 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.448 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.448 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.448 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.448 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.448 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.448 | |
| 4z36 | ON3 | Lysophosphatidic acid receptor 1 | / | 0.448 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.447 | |
| 2ab8 | ACP | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.447 | |
| 2owv | SAH | Diphthine synthase | / | 0.447 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.447 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.447 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.447 | |
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 1ngi | ANP | Heat shock cognate 71 kDa protein | / | 0.446 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2eeq | SAH | Diphthine synthase | / | 0.446 | |
| 2emr | SAH | Diphthine synthase | / | 0.446 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.446 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.446 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.446 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.446 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4eiq | KCT | Putative FAD-monooxygenase | / | 0.446 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.446 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1ats | ADP | Heat shock cognate 71 kDa protein | / | 0.445 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 3a6q | FMN | FMN-binding protein | / | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 4l8u | 9AZ | Serum albumin | / | 0.445 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.444 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.444 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2egs | SAH | Diphthine synthase | / | 0.444 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.444 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 2zrf | DTP | Protein RecA | / | 0.444 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.444 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.444 | |
| 3rdq | DTB | Streptavidin | / | 0.444 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.444 | |
| 5cns | CDP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.444 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.443 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.443 | |
| 2emu | SAH | Diphthine synthase | / | 0.443 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.443 | |
| 2zro | ADP | Protein RecA | / | 0.443 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.443 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.443 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.443 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 4ed4 | ATP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.443 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.443 | |
| 4jxr | ACO | Acetyltransferase | / | 0.443 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.443 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.442 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.442 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2dxw | SAH | Diphthine synthase | / | 0.442 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.442 | |
| 2owu | SAH | Diphthine synthase | / | 0.442 | |
| 2wd4 | TBV | Ascorbate peroxidase | / | 0.442 | |
| 2xvw | 9NR | Serum albumin | / | 0.442 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3qrm | NK7 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.442 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.442 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.441 | |
| 2e4n | SAH | Diphthine synthase | / | 0.441 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.441 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.441 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.441 | |
| 3zrl | ZRL | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.441 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.441 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.440 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.440 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.440 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.440 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |