sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 1.000 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.565 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.562 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.557 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.557 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.555 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.554 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.549 | |
| 4qec | NAP | ElxO | / | 0.549 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.545 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.544 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.540 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.538 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.525 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.523 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.519 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.514 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.509 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.507 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.504 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.503 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.501 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.499 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.497 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.497 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.495 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.492 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.491 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.491 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.490 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.486 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.486 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.485 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.485 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.481 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.479 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.478 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.478 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.478 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.478 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.478 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.477 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.476 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.475 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.475 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.474 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.473 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.473 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.471 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.471 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.470 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.469 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.469 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.469 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.468 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.467 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.467 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 1fml | RTL | Retinol dehydratase | / | 0.465 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.465 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.464 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.464 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.464 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.463 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.463 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.463 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.463 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.463 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.463 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.463 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.462 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.462 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.462 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.462 | |
| 5dp2 | NAP | CurF | / | 0.462 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.461 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.460 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.460 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.460 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.460 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.460 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.459 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.459 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.459 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.458 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.458 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.458 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.458 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.458 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.457 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.457 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.456 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.456 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.456 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.456 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.456 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.455 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.455 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.455 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.454 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.454 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.454 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.454 | |
| 4l4x | NDP | AmphI | / | 0.454 | |
| 4u7w | NDP | MxaA | / | 0.454 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.454 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.453 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.453 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.453 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.453 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.453 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.453 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.452 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.452 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.452 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 3e8x | NAP | BH1520 protein | / | 0.452 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.452 | |
| 4jic | FMN | GTN Reductase | / | 0.452 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.452 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.451 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.451 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.451 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.451 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.451 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.451 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.451 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.451 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.450 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.450 | |
| 3sju | NDP | Keto reductase | / | 0.450 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.450 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.450 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.450 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.449 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.449 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.447 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.447 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.447 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.447 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.447 | |
| 2zja | ACP | ATP-dependent DNA helicase Hel308 | / | 0.447 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.447 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.446 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.446 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.446 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.446 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.446 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.446 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.445 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.445 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.445 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 4y0k | NAP | AntE | / | 0.445 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.444 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.444 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.444 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.444 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.444 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.443 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.443 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.443 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.442 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.442 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.442 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.442 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.442 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.441 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.441 | |
| 5a3c | NAD | SIR2 family protein | / | 0.441 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.440 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.440 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.440 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.440 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.440 | |
| 4kwh | NAP | Reductase homolog | / | 0.440 | |
| 4y1b | NAP | AntE | / | 0.440 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 |