sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 1.000 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.624 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.546 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.539 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.534 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.523 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.519 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.518 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.517 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.515 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.511 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.510 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.508 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.508 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.507 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.507 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.507 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.506 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.505 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.503 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.502 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.502 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.502 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.501 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.501 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.500 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.500 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.499 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.499 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.498 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.498 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.498 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.498 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.496 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.496 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.496 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.494 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.493 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.492 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.492 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.488 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.488 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.488 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.486 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.485 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.483 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.483 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.482 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.482 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.481 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.481 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.481 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.481 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.481 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.480 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.479 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.479 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.479 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.478 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.477 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.477 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.477 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.477 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.476 | |
| 1zdw | FLV | Prenyltransferase | / | 0.476 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.476 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.476 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.476 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.475 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.475 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 1r2j | FAD | FkbI | / | 0.474 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 1eio | GCH | Gastrotropin | / | 0.472 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.472 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.471 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.471 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.471 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.470 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.470 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.468 | |
| 4h6p | FMN | Chromate reductase | / | 0.468 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 4mzu | TYD | WxcM-like protein | / | 0.467 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.466 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.465 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.464 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.464 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.464 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.463 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.463 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.463 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.462 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.462 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.461 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.461 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.461 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.460 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.460 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.460 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.460 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.457 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.456 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.456 | |
| 4up3 | NDP | Thioredoxin reductase | / | 0.456 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.455 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.455 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.454 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.453 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.453 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.453 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.452 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.452 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.451 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.450 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.450 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.450 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.450 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.449 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.449 | |
| 3b9l | AZZ | Serum albumin | / | 0.449 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.449 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.449 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.449 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.449 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.448 | |
| 1o1v | TCH | Gastrotropin | / | 0.448 | |
| 2bxq | IMN | Serum albumin | / | 0.448 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.448 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.447 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.447 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.446 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.446 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.446 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.446 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.445 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.445 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.445 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.445 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.445 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.445 | |
| 3q9o | NAD | Cholix toxin | 2.4.2.36 | 0.445 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.445 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.445 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 4pt3 | NDP | Aldehyde dehydrogenase | / | 0.445 | |
| 6prc | CEB | Reaction center protein L chain | / | 0.445 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.444 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.444 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.444 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.444 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.444 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.444 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 3awh | FMN | FMN-binding protein | / | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.442 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.442 | |
| 3p5s | AVU | CD38 molecule | / | 0.442 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.442 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2e77 | FMN | Lactate oxidase | / | 0.441 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.441 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.441 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.441 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.441 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.441 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.440 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 2xvv | 9DN | Serum albumin | / | 0.440 | |
| 2xvw | 9NR | Serum albumin | / | 0.440 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 |