Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fkpLS5Cyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fkpLS5Cyclin-dependent kinase 22.7.11.221.000
4fkq42KCyclin-dependent kinase 22.7.11.220.635
3s2pPMUCyclin-dependent kinase 22.7.11.220.596
3r1sX73Cyclin-dependent kinase 22.7.11.220.594
3qxoX65Cyclin-dependent kinase 22.7.11.220.589
2btsU32Cyclin-dependent kinase 22.7.11.220.587
3sqq99ZCyclin-dependent kinase 22.7.11.220.587
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.585
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.580
3rm719ZCyclin-dependent kinase 22.7.11.220.580
1ckpPVBCyclin-dependent kinase 22.7.11.220.579
3qtzX42Cyclin-dependent kinase 22.7.11.220.578
2btrU73Cyclin-dependent kinase 22.7.11.220.577
4ez30S0Cyclin-dependent kinase 22.7.11.220.577
3roy22ZCyclin-dependent kinase 22.7.11.220.575
4fkt48KCyclin-dependent kinase 22.7.11.220.575
1gih1PUCyclin-dependent kinase 22.7.11.220.574
3r71X86Cyclin-dependent kinase 22.7.11.220.574
3rjc06ZCyclin-dependent kinase 22.7.11.220.574
3iggEFQCyclin-dependent kinase 22.7.11.220.573
2w05FRTCyclin-dependent kinase 22.7.11.220.572
3qqfX07Cyclin-dependent kinase 22.7.11.220.570
1ke5LS1Cyclin-dependent kinase 22.7.11.220.569
4ek816KCyclin-dependent kinase 22.7.11.220.569
1pxmCK5Cyclin-dependent kinase 22.7.11.220.567
1oitHDTCyclin-dependent kinase 22.7.11.220.566
4ek610KCyclin-dependent kinase 22.7.11.220.566
1fvt106Cyclin-dependent kinase 22.7.11.220.565
2c6o4SPCyclin-dependent kinase 22.7.11.220.565
4fkr45KCyclin-dependent kinase 22.7.11.220.565
2w06FRVCyclin-dependent kinase 22.7.11.220.564
1ke8LS4Cyclin-dependent kinase 22.7.11.220.563
3rpv26ZCyclin-dependent kinase 22.7.11.220.563
1ke9LS5Cyclin-dependent kinase 22.7.11.220.561
3qzhX69Cyclin-dependent kinase 22.7.11.220.561
3r7yZ04Cyclin-dependent kinase 22.7.11.220.561
1ke7LS3Cyclin-dependent kinase 22.7.11.220.558
1p2a5BNCyclin-dependent kinase 22.7.11.220.558
3qqkX02Cyclin-dependent kinase 22.7.11.220.558
3r9dX6BCyclin-dependent kinase 22.7.11.220.558
2r64740Cyclin-dependent kinase 22.7.11.220.557
3r8lZ30Cyclin-dependent kinase 22.7.11.220.557
2r3p3SCCyclin-dependent kinase 22.7.11.220.556
3ddpRC8Cyclin-dependent kinase 22.7.11.220.556
3qu0X40Cyclin-dependent kinase 22.7.11.220.556
3rni21ZCyclin-dependent kinase 22.7.11.220.556
3r9hZ67Cyclin-dependent kinase 22.7.11.220.555
1vyzN5BCyclin-dependent kinase 22.7.11.220.554
3qxpX64Cyclin-dependent kinase 22.7.11.220.554
2a0cCK9Cyclin-dependent kinase 22.7.11.220.553
3qtuX44Cyclin-dependent kinase 22.7.11.220.553
1pxkCK3Cyclin-dependent kinase 22.7.11.220.550
3qzgX67Cyclin-dependent kinase 22.7.11.220.550
3raiX85Cyclin-dependent kinase 22.7.11.220.550
3lfnA27Cyclin-dependent kinase 22.7.11.220.549
2xmyCDKCyclin-dependent kinase 22.7.11.220.548
4acm7YGCyclin-dependent kinase 22.7.11.220.548
1h1r6CPCyclin-dependent kinase 22.7.11.220.547
2r3lSCWCyclin-dependent kinase 22.7.11.220.547
3unk0BYCyclin-dependent kinase 22.7.11.220.546
2w1hL0FCyclin-dependent kinase 22.7.11.220.545
3ral04ZCyclin-dependent kinase 22.7.11.220.545
2uzoC62Cyclin-dependent kinase 22.7.11.220.544
1oi9N20Cyclin-dependent kinase 22.7.11.220.542
1ke6LS2Cyclin-dependent kinase 22.7.11.220.540
2duv371Cyclin-dependent kinase 22.7.11.220.539
3r6xX84Cyclin-dependent kinase 22.7.11.220.539
3rak03ZCyclin-dependent kinase 22.7.11.220.539
4fx360KCyclin-dependent kinase 22.7.11.220.539
1h1s4SPCyclin-dependent kinase 22.7.11.220.538
2r3kSCQCyclin-dependent kinase 22.7.11.220.538
2r3iSCFCyclin-dependent kinase 22.7.11.220.536
3s1h56ZCyclin-dependent kinase 22.7.11.220.536
3r28XA0Cyclin-dependent kinase 22.7.11.220.534
3r73X87Cyclin-dependent kinase 22.7.11.220.534
1oiyN41Cyclin-dependent kinase 22.7.11.220.533
3qwjX6ACyclin-dependent kinase 22.7.11.220.533
2fvdLIACyclin-dependent kinase 22.7.11.220.532
2r3r6SCCyclin-dependent kinase 22.7.11.220.532
2r3gSC9Cyclin-dependent kinase 22.7.11.220.531
3qruX19Cyclin-dependent kinase 22.7.11.220.531
3unj0BXCyclin-dependent kinase 22.7.11.220.531
1w0xOLOCyclin-dependent kinase 22.7.11.220.530
2iw84SPCyclin-dependent kinase 22.7.11.220.530
3s0o50ZCyclin-dependent kinase 22.7.11.220.530
3sw418KCyclin-dependent kinase 22.7.11.220.530
4fki09KCyclin-dependent kinase 22.7.11.220.530
4lyn1YGCyclin-dependent kinase 22.7.11.220.530
2j9mPY8Cyclin-dependent kinase 22.7.11.220.529
1oguST8Cyclin-dependent kinase 22.7.11.220.528
4fko20KCyclin-dependent kinase 22.7.11.220.527
2c69CT8Cyclin-dependent kinase 22.7.11.220.526
2c6iDT1Cyclin-dependent kinase 22.7.11.220.525
3ezvEZVCyclin-dependent kinase 22.7.11.220.525
3lfsA07Cyclin-dependent kinase 22.7.11.220.525
3py0SU9Cyclin-dependent kinase 22.7.11.220.524
3r7vZ02Cyclin-dependent kinase 22.7.11.220.524
4bgh3I6Cyclin-dependent kinase 22.7.11.220.523
1v1k3FPCyclin-dependent kinase 22.7.11.220.522
3rk909ZCyclin-dependent kinase 22.7.11.220.522
1urwI1PCyclin-dependent kinase 22.7.11.220.521
3qx2X63Cyclin-dependent kinase 22.7.11.220.521
4fks46KCyclin-dependent kinase 22.7.11.220.521
3r7eX88Cyclin-dependent kinase 22.7.11.220.520
2b52D42Cyclin-dependent kinase 22.7.11.220.519
2r3mSCXCyclin-dependent kinase 22.7.11.220.519
3qtxX43Cyclin-dependent kinase 22.7.11.220.519
3r8vZ62Cyclin-dependent kinase 22.7.11.220.518
2c6mDT5Cyclin-dependent kinase 22.7.11.220.517
3pj8404Cyclin-dependent kinase 22.7.11.220.517
3r1yX76Cyclin-dependent kinase 22.7.11.220.517
4fkg4CKCyclin-dependent kinase 22.7.11.220.517
4fkj11KCyclin-dependent kinase 22.7.11.220.517
1fvv107Cyclin-dependent kinase 22.7.11.220.516
3r7uX96Cyclin-dependent kinase 22.7.11.220.516
3rk708ZCyclin-dependent kinase 22.7.11.220.515
3rmf20ZCyclin-dependent kinase 22.7.11.220.514
1pxpCK8Cyclin-dependent kinase 22.7.11.220.513
1ykr628Cyclin-dependent kinase 22.7.11.220.513
3qwkX62Cyclin-dependent kinase 22.7.11.220.513
1vyw292Cyclin-dependent kinase 22.7.11.220.511
2bheBRYCyclin-dependent kinase 22.7.11.220.511
3ig7EFPCyclin-dependent kinase 22.7.11.220.511
3rm618ZCyclin-dependent kinase 22.7.11.220.511
2vv9IM9Cyclin-dependent kinase 22.7.11.220.510
4kd11QKCyclin-dependent kinase 22.7.11.220.510
3ddqRRCCyclin-dependent kinase 22.7.11.220.509
3r1qX75Cyclin-dependent kinase 22.7.11.220.509
2a4lRRCCyclin-dependent kinase 22.7.11.220.508
2r3o2SCCyclin-dependent kinase 22.7.11.220.508
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.508
2w17I19Cyclin-dependent kinase 22.7.11.220.508
1oirHDYCyclin-dependent kinase 22.7.11.220.507
2iw94SPCyclin-dependent kinase 22.7.11.220.507
2uznC96Cyclin-dependent kinase 22.7.11.220.507
3rpy27ZCyclin-dependent kinase 22.7.11.220.507
3sw719KCyclin-dependent kinase 22.7.11.220.507
2wpa889Cyclin-dependent kinase 22.7.11.220.506
4eor4SPCyclin-dependent kinase 22.7.11.220.506
1e9hINRCyclin-dependent kinase 22.7.11.220.505
3rpo24ZCyclin-dependent kinase 22.7.11.220.505
1pxlCK4Cyclin-dependent kinase 22.7.11.220.504
2wxvWXVCyclin-dependent kinase 22.7.11.220.504
3qrtX14Cyclin-dependent kinase 22.7.11.220.504
4fkv61KCyclin-dependent kinase 22.7.11.220.504
2vu3LZECyclin-dependent kinase 22.7.11.220.503
3ezrEZRCyclin-dependent kinase 22.7.11.220.503
3rk507ZCyclin-dependent kinase 22.7.11.220.503
1h0w207Cyclin-dependent kinase 22.7.11.220.502
3ql8X01Cyclin-dependent kinase 22.7.11.220.502
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.501
1w8cN69Cyclin-dependent kinase 22.7.11.220.500
2r3jSCJCyclin-dependent kinase 22.7.11.220.500
4fkw62KCyclin-dependent kinase 22.7.11.220.500
3lfqA28Cyclin-dependent kinase 22.7.11.220.499
3qziX72Cyclin-dependent kinase 22.7.11.220.498
4bcmT7ZCyclin-dependent kinase 22.7.11.220.498
3qtrX36Cyclin-dependent kinase 22.7.11.220.497
3r8pZ46Cyclin-dependent kinase 22.7.11.220.497
3r9nZ68Cyclin-dependent kinase 22.7.11.220.497
4eok4SPCyclin-dependent kinase 22.7.11.220.497
1oiuN76Cyclin-dependent kinase 22.7.11.220.496
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.496
1g5sI17Cyclin-dependent kinase 22.7.11.220.495
1gii1PUCyclin-dependent kinase 22.7.11.220.495
1h1q2A6Cyclin-dependent kinase 22.7.11.220.494
1v0pPVBCell division control protein 2 homolog2.7.11.220.494
4cfnJYMCyclin-dependent kinase 22.7.11.220.494
4eol1ROCyclin-dependent kinase 22.7.11.220.493
3pxyJWSCyclin-dependent kinase 22.7.11.220.492
3r7iX9ICyclin-dependent kinase 22.7.11.220.490
1pkdUCNCyclin-dependent kinase 22.7.11.220.489
3dogNNNCyclin-dependent kinase 22.7.11.220.489
1oiqHDUCyclin-dependent kinase 22.7.11.220.488
1unlRRCCyclin-dependent-like kinase 52.7.11.10.488
2bhhRYUCyclin-dependent kinase 22.7.11.220.488
2x1nX1NCyclin-dependent kinase 22.7.11.220.488
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.488
3ti1B49Cyclin-dependent kinase 22.7.11.220.488
4bcnT9NCyclin-dependent kinase 22.7.11.220.488
4erwSTUCyclin-dependent kinase 22.7.11.220.488
1di8DTQCyclin-dependent kinase 22.7.11.220.487
1e1xNW1Cyclin-dependent kinase 22.7.11.220.487
2b55D31Cyclin-dependent kinase 22.7.11.220.487
3qqlX03Cyclin-dependent kinase 22.7.11.220.487
4eon1ROCyclin-dependent kinase 22.7.11.220.487
1y91CT9Cyclin-dependent kinase 22.7.11.220.486
3qqhX0ACyclin-dependent kinase 22.7.11.220.486
3rahO1ZCyclin-dependent kinase 22.7.11.220.486
2c4g514Cyclin-dependent kinase 22.7.11.220.485
3le62BZCyclin-dependent kinase 22.7.11.220.484
3tiz3TICyclin-dependent kinase 22.7.11.220.484
2r3fSC8Cyclin-dependent kinase 22.7.11.220.483
3rzb02ZCyclin-dependent kinase 22.7.11.220.483
1unhIXMCyclin-dependent-like kinase 52.7.11.10.482
3s00Z60Cyclin-dependent kinase 22.7.11.220.482
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.479
2r3q5SCCyclin-dependent kinase 22.7.11.220.479
2c6tDT5Cyclin-dependent kinase 22.7.11.220.478
3qtqX35Cyclin-dependent kinase 22.7.11.220.478
3u4uLNHCasein kinase II subunit alpha2.7.11.10.478
1aq1STUCyclin-dependent kinase 22.7.11.220.476
2wihP48Cyclin-dependent kinase 22.7.11.220.476
3uli1N3Cyclin-dependent kinase 22.7.11.220.476
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.475
2wotZZGTGF-beta receptor type-12.7.11.300.474
1h1pCMGCyclin-dependent kinase 22.7.11.220.473
3my5RFZCyclin-dependent kinase 22.7.11.220.473
2xnbY8LCyclin-dependent kinase 22.7.11.220.472
3r8uZ31Cyclin-dependent kinase 22.7.11.220.472
4eoi1ROCyclin-dependent kinase 22.7.11.220.471
1h0vUN4Cyclin-dependent kinase 22.7.11.220.470
1y8yCT7Cyclin-dependent kinase 22.7.11.220.470
3rpr25ZCyclin-dependent kinase 22.7.11.220.470
4bcpT3CCyclin-dependent kinase 22.7.11.220.470
3r8zZ63Cyclin-dependent kinase 22.7.11.220.469
1r78FMDCyclin-dependent kinase 22.7.11.220.466
3wblPDYCyclin-dependent kinase 22.7.11.220.466
4fv9E71Mitogen-activated protein kinase 12.7.11.240.466
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.464
2vtsLZCCyclin-dependent kinase 22.7.11.220.464
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.464
3qtwX3ACyclin-dependent kinase 22.7.11.220.464
1gij2PUCyclin-dependent kinase 22.7.11.220.463
3rkb12ZCyclin-dependent kinase 22.7.11.220.463
1pxoCK7Cyclin-dependent kinase 22.7.11.220.462
2vthLZ2Cyclin-dependent kinase 22.7.11.220.462
3fz1B98Cyclin-dependent kinase 22.7.11.220.462
3qzfX66Cyclin-dependent kinase 22.7.11.220.462
4eop1ROCyclin-dependent kinase 22.7.11.220.462
1pyePM1Cyclin-dependent kinase 22.7.11.220.461
2uzlC94Cyclin-dependent kinase 22.7.11.220.461
1dm2HMDCyclin-dependent kinase 22.7.11.220.460
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.460
3sheI85MAP kinase-activated protein kinase 32.7.11.10.459
4hgt15GCasein kinase I isoform delta2.7.11.10.459
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.459
2uzbC75Cyclin-dependent kinase 22.7.11.220.458
3qqgX06Cyclin-dependent kinase 22.7.11.220.458
4bcoT6QCyclin-dependent kinase 22.7.11.220.457
4gub0Y4Casein kinase II subunit alpha2.7.11.10.457
5dr6SKEAurora kinase A2.7.11.10.456
3qx4X4BCyclin-dependent kinase 22.7.11.220.455
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.455
2c5nCK8Cyclin-dependent kinase 22.7.11.220.454
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.454
2vtqLZACyclin-dependent kinase 22.7.11.220.454
3axwTIDCasein kinase II subunit alpha2.7.11.10.454
4c4f7CEDual specificity protein kinase TTK2.7.12.10.454
3qtsX46Cyclin-dependent kinase 22.7.11.220.453
4bcqTJFCyclin-dependent kinase 22.7.11.220.453
5dr9SKEAurora kinase A2.7.11.10.453
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.452
4eos1ROCyclin-dependent kinase 22.7.11.220.452
4qmpDKISerine/threonine-protein kinase 242.7.11.10.452
2vttLZDCyclin-dependent kinase 22.7.11.220.451
3at4CCKCasein kinase II subunit alpha2.7.11.10.451
1v0oINRCell division control protein 2 homolog2.7.11.220.450
2c68CT6Cyclin-dependent kinase 22.7.11.220.450
4eomATPCyclin-dependent kinase 22.7.11.220.450
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.450
2c5yMTWCyclin-dependent kinase 22.7.11.220.449
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.449
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.449
1hckATPCyclin-dependent kinase 22.7.11.220.448
3nup3NUCyclin-dependent kinase 62.7.11.220.448
3r9oZ71Cyclin-dependent kinase 22.7.11.220.448
2i40BLZCyclin-dependent kinase 22.7.11.220.447
2eufLQQCyclin-dependent kinase 62.7.11.220.446
2uzdC85Cyclin-dependent kinase 22.7.11.220.446
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.446
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.446
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.446
1k6cMK1Gag-Pol polyprotein3.4.23.160.444
2b53D23Cyclin-dependent kinase 22.7.11.220.444
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.444
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.444
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.443
3nwxKVSGag-Pol polyprotein3.4.23.160.443
4ez50RSCyclin-dependent kinase 62.7.11.220.443
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.442
2hog710Serine/threonine-protein kinase Chk12.7.11.10.442
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.442
2zjwREFCasein kinase II subunit alpha2.7.11.10.442
2wipP49Cyclin-dependent kinase 22.7.11.220.441
1b39ATPCyclin-dependent kinase 22.7.11.220.440
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.440
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
4c4g7RODual specificity protein kinase TTK2.7.12.10.440