sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase | / | 1.000 | |
| 4fj1 | GEN | 17beta-hydroxysteroid dehydrogenase | / | 0.628 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.624 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.615 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.598 | |
| 3qwh | KMP | 17beta-hydroxysteroid dehydrogenase | / | 0.573 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.504 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.497 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.496 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.493 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.490 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.485 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.481 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.480 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.479 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.477 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.475 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.473 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.472 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.471 | |
| 3u2l | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.471 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.469 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.467 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.466 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.466 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.466 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.466 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.465 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.465 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.465 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.464 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.464 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4lb2 | DM5 | Serum albumin | / | 0.464 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.463 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.463 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.463 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.462 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.461 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.461 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.461 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.461 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.461 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.460 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 2oym | MNI | Endoglycoceramidase II | / | 0.459 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.459 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.458 | |
| 1zdw | FLV | Prenyltransferase | / | 0.458 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.458 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.458 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.458 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.457 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3nly | 3XC | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.456 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.455 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.455 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.455 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 1ddt | APU | Diphtheria toxin | / | 0.454 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.454 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.454 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.454 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.453 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1srh | MOB | Streptavidin | / | 0.453 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.453 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.453 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.453 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4boe | CLR | Japanin | / | 0.453 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.453 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.452 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.452 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.452 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.451 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.451 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.451 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.451 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.451 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 1r2j | FAD | FkbI | / | 0.450 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.450 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.450 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.450 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.450 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.449 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.449 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.449 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.449 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.449 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3mbg | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.449 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.449 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.448 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.448 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.448 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.447 | |
| 2hj3 | FAD | FAD-linked sulfhydryl oxidase ERV1 | / | 0.447 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.447 | |
| 3uft | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.447 | |
| 4phl | PIL | Phosphodiesterase | / | 0.447 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.447 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.446 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.446 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.446 | |
| 2e20 | B4P | Propionate kinase | / | 0.446 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.446 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3p9t | TCL | Repressor | / | 0.446 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.446 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.445 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.445 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 1srf | MTB | Streptavidin | / | 0.444 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3aba | FLI | Cytochrome P450 | / | 0.444 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.444 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.444 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.443 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.443 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.443 | |
| 4dli | IRG | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4egn | TWO | Cytochrome P450 | / | 0.443 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4y9u | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.443 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.442 | |
| 1uhh | CZP | Aequorin-2 | / | 0.442 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.442 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.442 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.442 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.442 | |
| 3ufo | HW4 | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.441 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.441 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.441 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.441 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.441 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.441 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3c1o | NAP | Eugenol synthase | / | 0.441 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.441 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.441 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.441 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.440 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.440 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.440 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.440 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.440 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.440 |