sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 1.000 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.505 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.499 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.498 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.493 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.493 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.488 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.487 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.485 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.483 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.481 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.481 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.478 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.478 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.476 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.476 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.476 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.475 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.475 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.474 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.474 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.474 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.474 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.474 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.474 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.474 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.474 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.474 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.473 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.472 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.472 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.471 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.471 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.470 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.470 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.470 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.468 | |
| 1gqt | ACP | Ribokinase | / | 0.467 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.467 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.467 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.467 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.466 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.466 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.466 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.466 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.465 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.465 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.464 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.464 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.464 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.464 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.464 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.463 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.463 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.463 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.463 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.462 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.462 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.462 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.462 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.462 | |
| 1osv | CHC | Bile acid receptor | / | 0.461 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.461 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.460 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.460 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.460 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.460 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.459 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.459 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.459 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.459 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 5kj6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.458 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.458 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.458 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.458 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.458 | |
| 4dxh | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 4fd2 | ADP | Chaperone protein ClpB | / | 0.458 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.458 | |
| 4irn | FAD | AnaB | / | 0.458 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.457 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.457 | |
| 2oo5 | TXD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.457 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.457 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.457 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.457 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.456 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.456 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.456 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.456 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.456 | |
| 4nfs | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 5dp2 | NAP | CurF | / | 0.456 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.456 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.455 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.455 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.455 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.455 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.454 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.454 | |
| 3zuy | TCH | Transporter | / | 0.454 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.453 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.453 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.453 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.453 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.453 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.452 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.452 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.452 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.452 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.452 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.452 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.451 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.451 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.451 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.451 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 2y3r | TRK | TamL | / | 0.451 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.451 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.451 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.450 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.450 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.450 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.450 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.450 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.449 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.449 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.449 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.449 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.449 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.449 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.449 | |
| 5jjs | SAH | Genome polyprotein | / | 0.449 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.448 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.448 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.448 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.448 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.448 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.448 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.448 | |
| 5cdg | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.448 | |
| 1mgo | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.447 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.447 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1zdw | FLV | Prenyltransferase | / | 0.446 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.446 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.446 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.446 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.446 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.445 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.445 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3r95 | ACO | MccE protein | / | 0.445 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4c4o | NAD | SADH | / | 0.445 | |
| 4oaq | NDP | R-specific carbonyl reductase | / | 0.445 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.445 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.444 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.444 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2y3s | TIR | TamL | / | 0.444 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.444 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3eks | CY9 | Actin-5C | / | 0.444 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.444 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.444 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 4iae | 1DX | Alr2278 protein | / | 0.444 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.443 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.443 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.443 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.442 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.442 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.442 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2yvg | NAD | Ferredoxin reductase | / | 0.442 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.442 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 4k6m | SAH | Genome polyprotein | / | 0.442 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.442 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.441 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.441 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.441 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.441 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.441 | |
| 4p53 | NAI | 2-epi-5-epi-valiolone synthase | / | 0.441 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.441 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.440 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.440 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.440 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.440 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.440 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3wag | TYD | Glycosyltransferase | / | 0.440 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.440 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.440 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.440 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |