sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 1.408 | |
| 3tsc | NAD | Uncharacterized protein | / | 1.296 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 1.215 | |
| 3sx2 | NAD | Uncharacterized protein | / | 1.214 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 1.050 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 1.043 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.992 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.986 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.978 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.957 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.955 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.949 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.941 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.930 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.927 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.925 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.924 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.917 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.910 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.906 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.905 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.905 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.905 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.902 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.901 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.900 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.900 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.900 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.899 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.897 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.896 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.895 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.894 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.891 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.890 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.890 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.889 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.889 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.889 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.886 | |
| 1iy8 | NAD | Levodione reductase | / | 0.885 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.883 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.881 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.880 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.878 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.874 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.874 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.874 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.873 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.873 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.872 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.869 | |
| 3sju | NDP | Keto reductase | / | 0.869 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.869 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.867 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.863 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.860 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.856 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.855 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.855 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.854 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.852 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.852 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.850 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.849 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.847 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.846 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.843 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.843 | |
| 3mje | NDP | AmphB | / | 0.843 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.843 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.838 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.838 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.838 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.836 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.835 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.835 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.831 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.831 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.829 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.829 | |
| 1sny | NAP | LD36273p | / | 0.829 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.829 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.829 | |
| 4qec | NAP | ElxO | / | 0.828 | |
| 4qed | NAP | ElxO | / | 0.828 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.825 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.825 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.825 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.824 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.823 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.819 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.818 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.815 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.814 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.814 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.812 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.810 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.809 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.809 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.805 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.805 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.804 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.802 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.800 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.798 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.798 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.796 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.795 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.790 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.788 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.788 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.787 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.784 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.783 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.779 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.779 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.778 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.777 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.777 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.775 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.774 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.773 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.773 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.773 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.773 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.773 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.772 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.771 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.770 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.769 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.768 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.768 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.768 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.768 | |
| 4u7w | NDP | MxaA | / | 0.767 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.766 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.766 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.763 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.762 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.761 | |
| 4kwh | NAP | Reductase homolog | / | 0.761 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.760 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.760 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.759 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.759 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.758 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.757 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.756 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.752 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.752 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.751 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.751 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.751 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.750 | |
| 4hxy | NDP | Plm1 | / | 0.750 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.750 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.749 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.749 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.749 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.748 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.748 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.747 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.746 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.746 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.745 | |
| 3uce | NDP | Dehydrogenase | / | 0.745 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.742 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.740 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.740 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.739 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.739 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.736 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.735 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.735 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.734 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.734 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.731 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.731 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.730 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.729 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.728 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.728 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.727 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.726 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.723 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.723 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.721 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.717 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.717 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.716 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.713 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.712 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.710 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.710 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.708 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.708 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.707 | |
| 3bmo | NAP | Pteridine reductase | / | 0.707 | |
| 4clo | NAP | Pteridine reductase | / | 0.707 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.706 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.706 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.705 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.705 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.704 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.703 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.700 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.700 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.700 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.699 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.699 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.698 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.697 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 1xcb | NAD | Redox-sensing transcriptional repressor Rex | / | 0.694 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.693 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.692 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.692 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.691 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.690 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.690 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.690 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.690 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.689 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.689 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.687 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.685 | |
| 1lld | NAD | L-lactate dehydrogenase 2 | 1.1.1.27 | 0.684 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.684 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.684 | |
| 5d2e | NAP | MlnE | / | 0.684 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.683 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.683 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.682 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.682 | |
| 1la2 | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.681 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.681 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.681 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.681 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.681 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.680 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.679 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.678 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.678 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.676 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.676 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.675 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.675 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.674 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.673 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.673 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.672 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.671 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.671 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.670 | |
| 3qow | SAM | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.670 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.670 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.669 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.669 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.668 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.667 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.667 | |
| 1y8q | ATP | SUMO-activating enzyme subunit 2 | 6.3.2 | 0.666 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.666 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.665 | |
| 1zh8 | NAP | Uncharacterized protein | / | 0.665 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.664 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.664 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.663 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.663 | |
| 3qvt | NAI | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.663 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.662 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.661 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.661 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.661 | |
| 3c3y | SAH | O-methyltransferase | / | 0.661 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.661 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.660 | |
| 3abi | NAD | Uncharacterized protein | / | 0.660 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.659 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.659 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.658 | |
| 1rjg | SAH | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.657 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.657 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.656 | |
| 2hms | NAI | Ktr system potassium uptake protein A | / | 0.656 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.656 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.656 | |
| 5ccb | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.656 | |
| 1aqi | SAH | Modification methylase TaqI | 2.1.1.72 | 0.655 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.655 | |
| 4j49 | NAD | Uncharacterized protein | / | 0.655 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.655 | |
| 5e9w | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.655 | |
| 1zq9 | SAM | Probable dimethyladenosine transferase | / | 0.654 | |
| 4ek9 | EP4 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.654 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.654 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.654 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.653 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.653 | |
| 5a03 | NDP | Glucose-fructose oxidoreductase | / | 0.653 | |
| 3bwc | SAM | Spermidine synthase, putative | / | 0.651 | |
| 3sgl | SAM | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.651 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.651 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.650 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.650 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.650 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.650 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.650 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.650 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 |