sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yy7 | NAD | L-threonine dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2yy7 | NAD | L-threonine dehydrogenase | / | 1.319 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.931 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.907 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.865 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.827 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.816 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.816 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.812 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.811 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.790 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.788 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.787 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.783 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.781 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.779 | |
| 4u7w | NDP | MxaA | / | 0.778 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.776 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.775 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.773 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.772 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.767 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.766 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.765 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.764 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.763 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.763 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.762 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.762 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.762 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.761 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.761 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.760 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.760 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.758 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.758 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.756 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.756 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.755 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.755 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.754 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.753 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.753 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.750 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.750 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.749 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.749 | |
| 3mje | NDP | AmphB | / | 0.749 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.749 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.749 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.747 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.746 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.746 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.745 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.745 | |
| 4kwh | NAP | Reductase homolog | / | 0.744 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.743 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.742 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.741 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.740 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.740 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.739 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.739 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.738 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.737 | |
| 4qec | NAP | ElxO | / | 0.737 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.736 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.735 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.734 | |
| 2dt5 | NAD | Redox-sensing transcriptional repressor Rex | / | 0.731 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.731 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.730 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.730 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.730 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.729 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.729 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.728 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.727 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.727 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.726 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.726 | |
| 4qed | NAP | ElxO | / | 0.726 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.725 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.725 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.724 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.723 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.723 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.723 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.722 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.722 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.722 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.722 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.721 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.721 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.721 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.720 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.720 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.720 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.719 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.719 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.718 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.718 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.717 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.717 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.716 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.716 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.715 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.715 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.715 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.715 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.715 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.715 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.713 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.713 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.713 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.713 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.712 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.712 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.712 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.711 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.711 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.711 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.711 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.710 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.710 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.710 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.709 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.708 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.708 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.707 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.707 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.706 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.706 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.706 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.706 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.706 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.706 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.706 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.705 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.704 | |
| 1sny | NAP | LD36273p | / | 0.704 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.704 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.704 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.704 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.704 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.703 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.703 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.703 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.703 | |
| 1iy8 | NAD | Levodione reductase | / | 0.702 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.702 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.702 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.702 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.701 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.701 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.701 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.701 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.700 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.700 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.700 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.699 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.699 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.699 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.699 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.698 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.697 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.696 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.696 | |
| 3abi | NAD | Uncharacterized protein | / | 0.695 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.695 | |
| 1a71 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.694 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.694 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.694 | |
| 1y8q | ATP | SUMO-activating enzyme subunit 2 | 6.3.2 | 0.694 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.694 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.694 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.693 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.693 | |
| 1i36 | NAP | Conserved protein | / | 0.692 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.691 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.691 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.691 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.689 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.688 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.688 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.688 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.688 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.687 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.687 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.687 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.687 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.686 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.686 | |
| 1uay | ADN | Oxidoreductase | / | 0.686 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.686 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.686 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.685 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.685 | |
| 4nfh | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.685 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.684 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.684 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.684 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.683 | |
| 3uce | NDP | Dehydrogenase | / | 0.683 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.681 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.681 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.680 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.680 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.680 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 1la2 | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.679 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.679 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.679 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.679 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.679 | |
| 1sc6 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.678 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.677 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.677 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.677 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.676 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.675 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.675 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.675 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.675 | |
| 3sju | NDP | Keto reductase | / | 0.675 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.675 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.674 | |
| 1xcb | NAD | Redox-sensing transcriptional repressor Rex | / | 0.674 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.674 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.674 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.673 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.673 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.673 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 1ht0 | NAD | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.672 | |
| 2oxi | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.672 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.672 | |
| 3h5n | ATP | MccB protein | / | 0.672 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.672 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.672 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.671 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.671 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.671 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.671 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.671 | |
| 1wy7 | SAH | Uncharacterized protein | / | 0.670 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.670 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.670 | |
| 3bmo | NAP | Pteridine reductase | / | 0.670 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.670 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.670 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.669 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.669 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.669 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.669 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 4ros | APR | Malate dehydrogenase | / | 0.669 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.668 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.668 | |
| 5cdg | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.668 | |
| 5cds | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.668 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.667 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.667 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.667 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.667 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.666 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.666 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.665 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.665 | |
| 2cdu | ADP | NADH oxidase | / | 0.665 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.665 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.665 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.665 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.665 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.664 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.664 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.664 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.664 | |
| 3ec7 | NAD | Inositol 2-dehydrogenase | / | 0.664 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.664 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.664 | |
| 4xcx | SAH | Small RNA 2'-O-methyltransferase | / | 0.664 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.663 | |
| 4hxy | NDP | Plm1 | / | 0.663 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.663 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.662 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.661 | |
| 1zh8 | NAP | Uncharacterized protein | / | 0.661 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 2bm9 | SAM | Cephalosporin hydroxylase CmcI | / | 0.661 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.661 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.660 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.660 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.660 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.660 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.660 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.659 | |
| 2c5e | GDD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.659 | |
| 2dpm | SAM | Modification methylase DpnIIA | 2.1.1.72 | 0.659 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.659 | |
| 2qg4 | NAD | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.659 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.659 | |
| 4clo | NAP | Pteridine reductase | / | 0.659 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.659 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.658 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.658 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.658 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.658 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.657 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.657 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.657 | |
| 5ccx | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.657 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.656 | |
| 2hjr | APR | Malate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase | / | 0.656 | |
| 3h9j | APC | MccB protein | / | 0.655 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.655 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.654 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.654 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.654 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.654 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.653 | |
| 3adp | NAI | Lambda-crystallin | 1.1.1.45 | 0.653 | |
| 3wv8 | ATP | Hmd co-occurring protein HcgE | / | 0.653 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.653 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.652 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.652 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.652 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.652 | |
| 5d2e | NAP | MlnE | / | 0.652 | |
| 1j5p | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.651 | |
| 1ptj | SND | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.651 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.651 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.651 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.651 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.651 | |
| 4weq | NAP | NAD-dependent dehydrogenase | / | 0.651 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.651 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.650 | |
| 1lld | NAD | L-lactate dehydrogenase 2 | 1.1.1.27 | 0.650 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.650 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.650 | |
| 3tos | SAH | CalS11 | / | 0.650 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.650 |