Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ym1 FAD Phenylacetone monooxygenase 1.14.13.92

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2ym1 FADPhenylacetone monooxygenase 1.14.13.92 1.409
4d04 FADPhenylacetone monooxygenase 1.14.13.92 1.343
2yls FADPhenylacetone monooxygenase 1.14.13.92 1.323
4d03 FADPhenylacetone monooxygenase 1.14.13.92 1.306
2ylr FADPhenylacetone monooxygenase 1.14.13.92 1.276
2ym2 FADPhenylacetone monooxygenase 1.14.13.92 1.229
2ylx FADPhenylacetone monooxygenase 1.14.13.92 1.204
2ylw FADPhenylacetone monooxygenase 1.14.13.92 1.176
2ylt FADPhenylacetone monooxygenase 1.14.13.92 1.166
3gwd FADCyclohexanone monooxygenase / 0.923
3up4 FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.903
3uoz FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.865
3up5 FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.849
3uov FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.817
3uoy FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.801
3gwf FADCyclohexanone monooxygenase / 0.793
2jb1 FADL-amino acid oxidase / 0.788
3lzw FADFerredoxin--NADP reductase 2 1.18.1.2 0.780
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.776
2jae FADL-amino acid oxidase / 0.776
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.773
2dw4 FADLysine-specific histone demethylase 1A 1 0.769
1y56 ATPUncharacterized protein / 0.768
1gsn FADGlutathione reductase, mitochondrial 1.8.1.7 0.754
1zmd FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.754
1zx9 FADMercuric reductase 1.16.1.1 0.754
2eq6 FADDihydrolipoyl dehydrogenase / 0.752
4ap3 FADSteroid monooxygenase / 0.749
4guu FA9Lysine-specific histone demethylase 1B 1 0.749
1rp0 AHZThiamine thiazole synthase, chloroplastic / 0.748
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.741
2xls FADPutative flavin-containing monooxygenase / 0.740
2xvf FADPutative flavin-containing monooxygenase / 0.740
2eq8 FADDihydrolipoyl dehydrogenase / 0.738
3ada NADSubunit alpha of sarocosine oxidase / 0.738
3cge FADCoenzyme A disulfide reductase / 0.738
4aox FADSteroid monooxygenase / 0.737
1d4c FADFumarate reductase flavoprotein subunit 1.3.5.4 0.736
2r0c FADPutative FAD-monooxygenase / 0.736
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.734
1o94 ADPTrimethylamine dehydrogenase 1.5.8.2 0.732
1pdh FASp-hydroxybenzoate hydroxylase / 0.731
1f8r FADL-amino-acid oxidase 1.4.3.2 0.730
1grg FADGlutathione reductase, mitochondrial 1.8.1.7 0.730
4ap1 FADSteroid monooxygenase / 0.730
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.729
2eq9 FADDihydrolipoyl dehydrogenase / 0.729
3lxd FADFAD-dependent pyridine nucleotide-disulfide oxidoreductase / 0.727
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.726
2eq7 NADDihydrolipoyl dehydrogenase / 0.726
1zk7 FADMercuric reductase 1.16.1.1 0.725
2cvj FADThioredoxin reductase related protein / 0.725
3nlc FADUncharacterized protein / 0.725
4txi FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.725
1djn ADPTrimethylamine dehydrogenase 1.5.8.2 0.720
4tm3 FADKtzI / 0.720
1e1m FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.719
4b64 FADL-ornithine N(5)-monooxygenase / 0.719
1dnc FADGlutathione reductase, mitochondrial 1.8.1.7 0.718
3nt6 FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.718
4jdr FADDihydrolipoyl dehydrogenase 1.8.1.4 0.718
2gvc FADThiol-specific monooxygenase 1.14.13 0.717
3ef6 FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.717
3k30 ADPHistamine dehydrogenase / 0.715
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.714
3gyj FADCholesterol oxidase 1.1.3.6 0.714
4rek FADCholesterol oxidase 1.1.3.6 0.713
3f8p NADNADH oxidase/thioredoxin reductase / 0.711
4qi5 FADCellobiose dehydrogenase / 0.711
1gal FADGlucose oxidase 1.1.3.4 0.709
3hdy FADUDP-galactopyranose mutase / 0.708
3ukk FADUDP-galactopyranose mutase / 0.708
4xwr FADCholesterol oxidase 1.1.3.6 0.708
1ebd FADDihydrolipoyl dehydrogenase 1.8.1.4 0.706
1gra FADGlutathione reductase, mitochondrial 1.8.1.7 0.706
3dk8 FADGlutathione reductase, mitochondrial 1.8.1.7 0.706
3zdn FADMonoamine oxidase N 1.4.3.4 0.706
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.705
3cty FADProbable thioredoxin reductase / 0.705
3uox FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.705
5buk FADFADH2-dependent halogenase / 0.705
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.704
2xlr FADPutative flavin-containing monooxygenase / 0.704
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.704
3ish FADThioredoxin reductase 1.8.1.9 0.704
4fwf FADLysine-specific histone demethylase 1B 1 0.704
4jnq FDAThioredoxin reductase / 0.704
1n4u FAECholesterol oxidase 1.1.3.6 0.703
3cnj FADCholesterol oxidase 1.1.3.6 0.703
3gyi FADCholesterol oxidase 1.1.3.6 0.703
3l8k ADPDihydrolipoamide dehydrogenase (PdhD-3) / 0.703
3f8r NAPNADH oxidase/thioredoxin reductase / 0.701
4wx1 FDAUDP-galactopyranose mutase / 0.701
1nhr FADNADH peroxidase 1.11.1.1 0.699
2bry FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.699
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.698
1mo9 FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.697
1n4v FADCholesterol oxidase 1.1.3.6 0.697
1n1p FADCholesterol oxidase 1.1.3.6 0.696
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.696
4z26 FADPutative GMC-type oxidoreductase R135 1 0.696
2e1m FADL-glutamate oxidase / 0.695
4fwe FADLysine-specific histone demethylase 1B 1 0.695
1gre FADGlutathione reductase, mitochondrial 1.8.1.7 0.694
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.694
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.694
1get FADGlutathione reductase 1.8.1.7 0.693
2gew FADCholesterol oxidase 1.1.3.6 0.693
2zzc FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.693
3jsk AHZThiamine thiazole synthase / 0.693
3t2y FADSulfide-quinone reductase / 0.693
5br7 FADUDP-galactopyranose mutase / 0.693
4eqx FADCoenzyme A disulfide reductase / 0.692
5fs9 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.692
1h81 FADPolyamine oxidase 1.5.3.14 0.691
1ijh FADCholesterol oxidase 1.1.3.6 0.691
4b69 FADL-ornithine N(5)-monooxygenase / 0.691
1bwc FADGlutathione reductase, mitochondrial 1.8.1.7 0.690
2rgj FADFlavin-containing monooxygenase / 0.689
5hhf FDAUDP-galactopyranose mutase / 0.689
1zmc NADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.688
4u2s FDACholesterol oxidase 1.1.3.6 0.688
4dsg FADUncharacterized protein / 0.686
2xlp FADPutative flavin-containing monooxygenase / 0.685
3icr FADCoenzyme A disulfide reductase / 0.685
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.685
4qi7 FADCellobiose dehydrogenase / 0.685
4yac NAIC alpha-dehydrogenase / 0.684
3ute FADUDP-galactopyranose mutase / 0.683
4gus FADLysine-specific histone demethylase 1B 1 0.683
4twr NADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase / 0.683
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.681
1jki NAIInositol-3-phosphate synthase 5.5.1.4 0.681
2fjb SFDAdenylylsulfate reductase, subunit A (AprA) / 0.681
3r9u FADThioredoxin reductase / 0.681
4icy FADPgaE / 0.681
5cku FADL-ornithine N(5)-monooxygenase / 0.681
4gcm FADThioredoxin reductase 1.8.1.9 0.679
4qi4 FADCellobiose dehydrogenase / 0.679
1e6e FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.678
3cgd FADCoenzyme A disulfide reductase / 0.678
1ges FADGlutathione reductase 1.8.1.7 0.677
3sgl FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.677
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.676
3utg FDAUDP-galactopyranose mutase / 0.676
2igo FADPyranose 2-oxidase / 0.675
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.675
3jyo NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.675
2c3c FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.674
3ict FADCoenzyme A disulfide reductase / 0.674
4hsu FADLysine-specific histone demethylase 1B 1 0.674
4u8l FDAUDP-galactopyranose mutase / 0.674
2x3n FADProbable FAD-dependent monooxygenase / 0.673
4eqs FADCoenzyme A disulfide reductase / 0.673
4tlz FADKtzI / 0.673
2xvi FADPutative flavin-containing monooxygenase / 0.672
2gv8 FADThiol-specific monooxygenase 1.14.13 0.671
2vvl FADMonoamine oxidase N 1.4.3.4 0.671
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.671
3fg2 FADPutative rubredoxin reductase / 0.671
4aos FADSteroid monooxygenase / 0.671
5l3d FADLysine-specific histone demethylase 1A 1 0.671
1gpe FADGlucose oxidase 1.1.3.4 0.670
1nhq FADNADH peroxidase 1.11.1.1 0.670
5hsa FASAlcohol oxidase 1 1.1.3.13 0.670
1n4w FADCholesterol oxidase 1.1.3.6 0.669
2hqm FADGlutathione reductase 1.8.1.7 0.669
4mih FADPyranose 2-oxidase 1.1.3.10 0.669
3dk9 FADGlutathione reductase, mitochondrial 1.8.1.7 0.668
2bi7 FADUDP-galactopyranose mutase 5.4.99.9 0.667
2bra FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.667
3ukl FADUDP-galactopyranose mutase / 0.667
2fjd SFDAdenylylsulfate reductase, subunit A (AprA) / 0.665
2uxx FAJLysine-specific histone demethylase 1A 1 0.665
3pl8 FADPyranose 2-oxidase / 0.665
4u8n FDAUDP-galactopyranose mutase / 0.665
3rnm FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.664
4gr1 FADGlutathione reductase, mitochondrial 1.8.1.7 0.664
3k4c FADPyranose 2-oxidase / 0.663
4u8o FDAUDP-galactopyranose mutase / 0.663
1c0k FADD-amino-acid oxidase 1.4.3.3 0.662
2tmd ADPTrimethylamine dehydrogenase 1.5.8.2 0.662
3sz0 FADSulfide-quinone reductase / 0.662
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.661
1reo FADL-amino-acid oxidase 1.4.3.2 0.660
2b9y FADPutative aminooxidase / 0.660
2f5z FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.660
2gr3 FADFerredoxin reductase / 0.660
3ab1 FADFerredoxin--NADP reductase 1.18.1.2 0.660
3grs FADGlutathione reductase, mitochondrial 1.8.1.7 0.660
4gde FDAUDP-galactopyranose mutase / 0.660
4u8m FDAUDP-galactopyranose mutase / 0.660
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.659
2yg4 FADPutrescine oxidase / 0.659
3lsi FADPyranose 2-oxidase / 0.659
2fja FADAdenylylsulfate reductase, subunit A (AprA) / 0.658
3lad FADDihydrolipoyl dehydrogenase / 0.658
4eqw FADCoenzyme A disulfide reductase / 0.658
1djq ADPTrimethylamine dehydrogenase 1.5.8.2 0.657
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.657
1wam FADUDP-galactopyranose mutase 5.4.99.9 0.657
4fwj FADLysine-specific histone demethylase 1B 1 0.657
4o5q FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.657
3lzx FADFerredoxin--NADP reductase 2 1.18.1.2 0.656
2vqb FADPutative flavin-containing monooxygenase / 0.655
2yvf FADFerredoxin reductase / 0.655
3lb8 FADPutidaredoxin reductase 1.18.1.5 0.655
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.655
3t37 FADPyridoxine 4-oxidase / 0.655
3vqr FADPutative oxidoreductase / 0.655
4u2l SFDCholesterol oxidase 1.1.3.6 0.655
4em4 FADCoenzyme A disulfide reductase / 0.654
4opt FDAConserved Archaeal protein / 0.654
2iid FADL-amino-acid oxidase 1.4.3.2 0.653
2vq7 FADPutative flavin-containing monooxygenase / 0.653
2ywl FADThioredoxin reductase related protein / 0.653
3urh FADDihydrolipoyl dehydrogenase / 0.653
4ccq FADThioredoxin reductase / 0.652
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.651
2gr1 FADFerredoxin reductase / 0.651
4gur FADLysine-specific histone demethylase 1B 1 0.651
2x8h FADThioredoxin glutathione reductase / 0.650
4b67 FADL-ornithine N(5)-monooxygenase / 0.650
4u2t FADCholesterol oxidase 1.1.3.6 0.650