sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nh9 | 2LC | Endoplasmin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4nh9 | 2LC | Endoplasmin | / | 1.000 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.548 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.524 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.523 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.512 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.501 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.496 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.490 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 4l8u | 9AZ | Serum albumin | / | 0.485 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.481 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.481 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.475 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.475 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.475 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.474 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.473 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.473 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.473 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.472 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.472 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.471 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.470 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.470 | |
| 3cxh | SMA | Cytochrome b | / | 0.469 | |
| 3eel | 53T | Uncharacterized protein | / | 0.469 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.469 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.469 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.468 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.468 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.468 | |
| 1kyo | SMA | Cytochrome b | / | 0.467 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.467 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.466 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.466 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.466 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.466 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.465 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.463 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.463 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.462 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.462 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.461 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.461 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 2yiu | SMA | Cytochrome b | / | 0.461 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.461 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.459 | |
| 3cse | N22 | Uncharacterized protein | / | 0.459 | |
| 3cx5 | SMA | Cytochrome b | / | 0.459 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.459 | |
| 3p9t | TCL | Repressor | / | 0.459 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.458 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.458 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.457 | |
| 3lu8 | IQX | Serum albumin | / | 0.457 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.457 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.457 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.457 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.456 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.456 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.456 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.455 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.455 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.455 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.455 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4l9q | 9TP | Serum albumin | / | 0.454 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.453 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.453 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3s1c | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.453 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.453 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.453 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.453 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.453 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.452 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.452 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.452 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.452 | |
| 4kwh | NAP | Reductase homolog | / | 0.452 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.451 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.451 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.451 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.451 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.450 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.450 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.450 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.450 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.450 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.449 | |
| 3h18 | PMS | Esterase/lipase | / | 0.449 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.449 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4ldk | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.449 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1tg5 | 645 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.448 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3tgu | WF3 | Cytochrome b | / | 0.448 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.448 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.447 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.447 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.447 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.447 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.447 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.447 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.446 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.446 | |
| 3eek | 53S | Uncharacterized protein | / | 0.446 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.446 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.446 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.446 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.446 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.446 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.446 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.445 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.445 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.445 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3vnt | 0JA | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.444 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.444 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.443 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.443 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.443 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.443 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.443 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.443 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.443 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1p7t | ACO | Malate synthase G | / | 0.442 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 2bx8 | AZQ | Serum albumin | / | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2qjy | SMA | Cytochrome b | / | 0.442 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.442 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.442 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.442 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.441 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.441 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.441 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.441 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.441 | |
| 4o7u | THF | Thymidylate synthase | / | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.441 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.440 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 1oqc | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.440 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.440 | |
| 2wpw | ACO | Orf14 | / | 0.440 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.440 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.440 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.440 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.440 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.440 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.440 |